Sofpironium Bromide
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Sofpironium bromide, sold under the brand name Ecclock among others, is a
medication Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmaco ...
used to treat
hyperhidrosis Hyperhidrosis is a medical condition in which a person exhibits excessive perspiration, sweating, more than is required for the Thermoregulation, regulation of body temperature. Although it is primarily a physical burden, hyperhidrosis can deterio ...
(excessive sweating). Sofpironium bromide is an
anticholinergic Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central nervous system, central and peripheral nervous system. These agents inhibit the parasympatheti ...
agent that is applied to the skin. It was approved for medical use in Japan in 2020, and in the United States in June 2024.


Medical uses

Sofpironium bromide is
indicated In medicine, an indication is a valid reason to use a certain test, medication, procedure, or surgery. There can be multiple indications to use a procedure or medication. An indication can commonly be confused with the term diagnosis. A diagnosis ...
for the treatment of primary axillary hyperhidrosis.


Mechanism of action

The pharmacodynamics of sofpironium bromide are unknown.


Society and culture


Legal status

It was approved for medical use in Japan in November 2020, and in the United States in June 2024.


Brand names

Sofpironium bromide is the international nonproprietary name. It is sold under the brand name Ecclock in Japan and under the brand name Sofdra in the US.


References


Further reading

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External links

* * * {{DEFAULTSORT:Sofpironium Bromide Dermatologic drugs Muscarinic antagonists Quaternary ammonium compounds Bromides Pyrrolidines Tertiary alcohols Carboxylate esters Ethyl esters Cyclopentyl compounds