Silent Spring Institute
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Silent Spring Institute is a nonprofit organization dedicated to studying and reporting primarily on breast cancer prevention, although its research covers other health-related topics as well.


Founding and purpose

The nonprofit organization was founded in 1994 "as an outgrowth of the Massachusetts Breast Cancer Coalition."Cynthia McCormick, "Silent Spring Institute Seeks More State Support," ''Cape Cod Times,'' October 20, 2014
/ref> It engages in research on the links between risk of breast cancer and exposure to chemicals found in everyday products."Newton's Silent Spring Institute Celebrates 20th Anniversary," ''Wicked Local Newton,'' November 28, 2014
/ref> Its scientific team does field testing on
Cape Cod Cape Cod is a peninsula extending into the Atlantic Ocean from the southeastern corner of Massachusetts, in the northeastern United States. Its historic, maritime character and ample beaches attract heavy tourism during the summer months. The ...
and collaborates with private and academic laboratories. In 2014 the ''
Cape Cod Times The ''Cape Cod Times'' is a broadsheet daily newspaper serving Barnstable County, Massachusetts, United States, which encompasses 15 towns on Cape Cod with a year-round population of about 230,000 and a circulation of about 20,000. It is owned ...
'' recalled that:
From the start, Silent Spring Institute researchers were interested in whether environmental toxins were having a particular influence on the Cape's drinking water, which is served by a sole source aquifer and leaches through sandy soil that in theory allows wastewater – and contaminants – to drain into the water supply more quickly than through other types of soil. Silent Spring researchers have tested water in public and private wells for the presence of chemicals known as emerging contaminants and have visited scores of Cape homes to measure for the presence of hormone-disrupting chemicals.
Based in
Newton, Massachusetts Newton is a city in Middlesex County, Massachusetts, United States. It is located roughly west of Downtown Boston, and comprises a patchwork of thirteen villages. The city borders Boston to the northeast and southeast (via the neighborhoods of ...
, the institute was named in honor of environmentalist
Rachel Carson Rachel Louise Carson (May 27, 1907 – April 14, 1964) was an American marine biologist, writer, and conservation movement, conservationist whose sea trilogy (1941–1955) and book ''Silent Spring'' (1962) are credited with advancing mari ...
, who died of
breast cancer Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...
.Trevor Butterworth, "BPA A Concern For Breast Cancer? Not According To Study By Leading Environmental Group," ''Forbes'', June 12, 2014
/ref>


Research


Background

The only independent research institute dedicated to studying breast cancer prevention, Silent Spring Institute has established a reputation for exemplary research. In keeping with Silent Spring's commitment to collaboration between scientists and activists, researchers report individual exposure results to all individuals and communities participating in its studies. It has become a pioneer in developing ethical methods for communicating results when the health implications are uncertain. In 2000, Silent Spring's research was honored with a
U.S. Environmental Protection Agency The Environmental Protection Agency (EPA) is an independent agency of the United States government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it began operation on De ...
Environmental Merit Award. The papers of Silent Spring Institute from 1988 to 2006 are archived at the
Schlesinger Library The Arthur and Elizabeth Schlesinger Library on the History of Women in America is a research library at Harvard Radcliffe Institute at Harvard University. According to Nancy F. Cott, the Carl and Lily Pforzheimer Foundation Director, it is "the ...
at Harvard, which has prepared a detailed finding aid.


Projects

* The institute partnered with the
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (LBNL, Berkeley Lab) is a Federally funded research and development centers, federally funded research and development center in the Berkeley Hills, hills of Berkeley, California, United States. Established i ...
in a research project on "Chemicals and Breast Cancer: Building on National Initiatives for Chemical Safety Screening," which focused on the development of rapid ''
in vitro ''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in ...
'' screens for breast carcinogens in
mammary A mammary gland is an exocrine gland that produces milk in humans and other mammals. Mammals get their name from the Latin word ''mamma'', "breast". The mammary glands are arranged in organs such as the breasts in primates (for example, humans ...
cells. A report was published in 2014.Jennifer McPartland, Heather C. Dantzker and Christopher J. Portier, "Building a Robust 21st Century Chemical Testing Program at the U.S. Environmental Protection Agency: Recommendations for Strengthening Scientific Engagement," ''Environmental Health Perspectives,'' October 24, 2014
/ref> * Researchers from the institute and from the
University of Antwerp The University of Antwerp () is a major Belgian university located in the city of Antwerp. The official abbreviation is ''UAntwerp''. The University of Antwerp has about 20,000 students, which makes it the third-largest university in Flanders. ...
, Belgium, reported in 2014 that there had been "limited information" about Americans' exposure to phosphate
flame retardants Flame retardants are a diverse group of chemicals that are added to manufactured materials, such as plastics and textiles, and surface finishes and coatings. Flame retardants are activated by the presence of an combustion, ignition source and pr ...
and how such exposure might affect their health, so in 2011 a urine analysis and study was made of sixteen California residents, and all were found to have traces of three harmful chemicals – bis-(1,3-dichloro-2-propyl) phosphate ( BDCIPP), tris-(1,3-dichloro-isopropyl) phosphate ( TDCIPP) and bis-(2-chloroethyl) phosphate ( BCEP). :The lead researcher, the institute's Robin Dodson, said: "We found that several toxic
flame retardants Flame retardants are a diverse group of chemicals that are added to manufactured materials, such as plastics and textiles, and surface finishes and coatings. Flame retardants are activated by the presence of an combustion, ignition source and pr ...
are in people's bodies. When you sit on your couch, you want to relax, not get exposed to chemicals that may cause
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
. ''Medical News Today'' said that "Flame retardant chemicals are found in a variety of products that we come into contact with every day, such as
carpets A carpet is a textile floor covering typically consisting of an upper layer of Pile (textile), pile attached to a backing. The pile was traditionally made from wool, but since the 20th century synthetic fiber, synthetic fibres such as polyprop ...
, sofas, curtains and even baby products. The chemicals were introduced to these products in the 1970s to reduce the likelihood of ignitability." It noted that another chemical, tris-(2-chloroethyl) phosphate (
TCEP TCEP (tris(2-carboxyethyl)phosphine) is a reducing agent frequently used in biochemistry and molecular biology applications. It is often prepared and used as a hydrochloride salt (chemistry), salt (TCEP-HCl) with a molecular weight of 286.65 gra ...
), "known to cause cancer and reproductive problems in humans," was found in about 75% if the subjects and that it had "never before been discovered in Americans." ''Counsel and Health'' noted that "The team also found that residents with the highest levels of TCEP and TDCIPP in their urine lived in homes that had respective chemical in dust, which suggests that the home and the furniture in it are exposing people to toxic flame retardants."Honor Whiteman, "Researchers Discover Type of Toxic Flame Retardant in Americans for First Time," ''Medical News Today,'' November 15, 2014
/ref>
/ref> ttps://www.sciencedaily.com/releases/2014/11/141112084506.htm A Previously Unrecognized Flame Retardant Found in Americans for the First Time, ''Science Daily,'' November 12, 2014/ref> :''Medical News Today'' concluded: :
The researchers note that there are strategies consumers can adopt to reduce their exposure to toxic flame retardants. Because the chemicals are likely to gather in dust, they recommend that individuals use a
vacuum A vacuum (: vacuums or vacua) is space devoid of matter. The word is derived from the Latin adjective (neuter ) meaning "vacant" or "void". An approximation to such vacuum is a region with a gaseous pressure much less than atmospheric pressur ...
with a high-efficiency particulate air (HEPA) filter to vacuum their homes. This filter traps particles, rather than recirculate them back into the air. They also recommend that people throw away any foam that is deteriorating in their households, as it is possible such products may emit higher levels of toxic chemicals.
:The study was published in the journal ''
Environmental Science & Technology ''Environmental Science & Technology'' is a biweekly peer-reviewed scientific journal published since 1967 by the American Chemical Society. It covers research in environmental science and environmental technology, including environmental policy. ...
.'' * Early in 2014 the institute published a paper in ''
Environmental Health Perspectives ''Environmental Health Perspectives'' (''EHP'') is a peer-reviewed Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work ( peers). It functions as a form of self-regulation by qual ...
'' that listed "17 types of chemicals to avoid, including those in
gasoline Gasoline ( North American English) or petrol ( Commonwealth English) is a petrochemical product characterized as a transparent, yellowish, and flammable liquid normally used as a fuel for spark-ignited internal combustion engines. When for ...
,
diesel exhaust Diesel exhaust is the exhaust gas produced by a diesel engine, plus any contained particulates. Its composition may vary with the fuel type, rate of consumption or speed of engine operation (e.g., idling or at speed or under load), and whether ...
, flame retardants and
paint thinner Paint thinners are diluents — solvents used to adjust the viscosity of paint, as well as similar preparations such as varnish and lacquer, by dilution. For water-based paints, such as acrylic paints, water is the primary solvent, but notably, ...
." ''Forbes'' magazine called the paper a "massive synthesis of data from the
National Toxicology Program The National Toxicology Program (NTP) is an inter-agency program run by the United States Department of Health and Human Services to coordinate, evaluate, and report on toxicology within public agencies. The National Toxicology Program is head ...
and consensus reports from international cancer authorities" which "identified 102 chemicals as critical for breast cancer research and prevention." The institute said the study was "a road map for breast cancer prevention by identifying high-priority chemicals and evaluating tools to measure exposure." :In 2014, Silent Spring published
list of 100 breast carcinogens
with widespread exposure and identified methods to measure them in people, providing a road map for breast cancer research and policies to reduce exposure. :The authors of the study were Ruthann A. Rudel, Janet M. Ackerman and Julia Green Brody of the Silent Spring Institute and Kathleen R. Attfield of the
Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school at Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. It was named after Hong Kong entrepreneur Chan Tseng-hsi in 2014 following a US$350 ...
.
United Press International United Press International (UPI) is an American international news agency whose newswires, photo, news film, and audio services provided news material to thousands of newspapers, magazines, radio and television stations for most of the 20th ce ...
summed up its results by stating: "Gasoline and chemicals formed by combustion from vehicles, lawn equipment, smoking and charred food are among the largest sources of mammary carcinogens in the environment."Alex Cukin, "Study: Everyday Chemicals That May Increase Breast Cancer Risk," United Press International, May 13, 2014
/ref> In detail, these carcinogens included: :
Solvents, such as
methylene chloride Dichloromethane (DCM, methylene chloride, or methylene bichloride) is an organochlorine compound with the formula . This colorless, volatile liquid with a chloroform-like, sweet odor is widely used as a solvent. Although it is not miscible with ...
and other
halogenated In chemistry, halogenation is a chemical reaction which introduces one or more halogens into a chemical compound. Halide-containing compounds are pervasive, making this type of transformation important, e.g. in the production of polymers, drugs ...
organic solvents used in spot removers, specialty cleaners and industrial degreasers. Pharmaceutical hormones such as hormone replacement therapy; certain flame retardants used in furniture; a chemical used in stain-resistant textiles and non-stick coatings; and styrene found in tobacco smoke and also used to make Styrofoam. Drinking water. It can contain mammary carcinogens, such disinfection by-products or solvents.
* In 2013 the ''
Science of the Total Environment Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...
'' journal published a study led by institute scientist Laurel Schaider that "looked at emerging contaminants in
septic systems A septic tank is an underground chamber made of concrete, fiberglass, or plastic through which domestic wastewater (sewage) flows for basic sewage treatment. Settling and anaerobic digestion processes reduce solids and organics, but the treatment ...
" on Cape Cod and their impact on water wells. It found that "
Caffeine Caffeine is a central nervous system (CNS) stimulant of the methylxanthine chemical classification, class and is the most commonly consumed Psychoactive drug, psychoactive substance globally. It is mainly used for its eugeroic (wakefulness pr ...
and
acetaminophen Paracetamol, or acetaminophen, is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Parac ...
were very well removed" by sewage treatment but "Not so well removed were an antibiotic containing
sulfa Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs. The original antibacterial sulfonamides are synthetic antimicrobial agents th ...
, and
PFOS Perfluorooctanesulfonic acid (PFOS) (conjugate base perfluorooctanesulfonate) is a chemical compound having an eight-carbon fluorocarbon chain and a sulfonic acid functional group, and thus it is a perfluorosulfonic acid and a perfluoroalkyl su ...
, a chlorinated flame retardant commonly used in a number of home stain-resistant and nonstick coatings, as well as firefighting foams." It was "estimated that 80–85 percent of nitrogen comes from human waste not being properly processed via the Cape’s septic systems."Kathleen Szmit, "What's in Your Water?" ''The Barnstable Patriot,'' September 20, 2013
* A study by the institute, reported in 2012, found that a test of 50 household products such as cleaners,
cosmetics Cosmetics are substances that are intended for application to the body for cleansing, beautifying, promoting attractiveness, or altering appearance. They are mixtures of chemical compounds derived from either Natural product, natural source ...
and personal-care products found a "troubling amount" of "potentially harmful" products. Julia Brody of the institute advised consumers to avoid "antimicrobial products like some hand sanitizers and soaps" and "many products that contain fragrances." According to a television news report, "Silent Spring says look for '
paraben Parabens are organic compounds that are commonly used as preservatives in cosmetic and pharmaceutical products. They are esters of parahydroxybenzoic acid (also known as 4-hydroxybenzoic acid). Chemistry Structure and structure Parabens a ...
-free' products when shopping for deodorant, shampoo or cosmetics, and avoid vinyl products especially pillow and mattress protectors. The problem, the study finds, is that manufacturers are not required to list all ingredients."Kate Merrill, "Study: Harmful Chemicals Left Off Household Product Labels," CBS Boston: WBZ News Radio, March 8, 2012
/ref> : Industry groups responded quickly and negatively: The International Fragrance Association of North America said the study was "an example of biased, advocacy based research," and the
Personal Care Products Council The Personal Care Products Council (PCPC) is an American trade association. The PCPC was founded in 1894 as the Manufacturing Perfumers' Association, renamed the American Manufacturers of Toilet Articles (AMTA) in 1922, and renamed again as the C ...
said that "equating the mere presence of chemicals in products with potential harm is wrong and needlessly scares consumers." *In 2007, Silent Spring published a database of 216 chemicals that cause mammary gland tumors in animal studies. Dubbed "the breast cancer list" by ''Science'' magazine, the study made headlines by highlighting new hypotheses about environmental risks and showing that common exposures, including diesel and
benzene Benzene is an Organic compound, organic chemical compound with the Chemical formula#Molecular formula, molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar hexagonal Ring (chemistry), ring with one hyd ...
in gasoline, were biologically plausible links to breast cancer. * In its first decade, the research team focused on identifying biologically suspect chemicals and measuring personal exposure. Silent Spring's 2003 Household Exposure Study (HES) was the first and most comprehensive assessment of
endocrine disruptor Endocrine disruptors, sometimes also referred to as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds are chemicals that can interfere with endocrine (or hormonal) systems. These disruptions can cause ...
s in homes; it documented consumer products as the primary source of the chemicals. * Silent Spring began by investigating the links between hormone disruptors and human health among women on Cape Cod. The study, published in 2004, showed that the longer that women lived on Cape Cod, the higher was their breast cancer risk.McKelvey, W., J.G. Brody, A. Aschengrau, and C.H. Swartz (2004) "Association between Residence on Cape Cod, Massachusetts, and Breast Cancer", in ''Annals of Epidemiology'', 14 (2), pp.89–94


Other activities

The organization celebrated its twentieth anniversary on October 20, 2014, with a fund-raising dinner at the Royal Sonesta Hotel in Cambridge, Massachusetts. Speakers included ''New York Times'' journalist
Nicholas Kristof Nicholas Donabet Kristof (born April 27, 1959) is an American journalist and political commentator. A winner of two Pulitzer Prizes, he is a regular CNN contributor and an op-ed columnist for ''The New York Times''. Born in Chicago, Kristof wa ...
, author Florence Williams and institute director Julia Brody. Ellen Parker of Newton, the chair of the institute's board, received its Rachel Carson Advocacy Award. Reporter Kelley Tuthill of radio station
WCVB WCVB-TV (channel 5) is a television station in Boston, Massachusetts, United States, affiliated with ABC and owned by Hearst Television. The station's studios are located on TV Place (off Gould Street near the I-95/ MA 128/Highland Avenue inte ...
was the master of ceremonies.


Leadership

In late 2014 Julia Brody was executive director, and Cynthia Barakatt was chair of the
board Board or Boards may refer to: Flat surface * Lumber, or other rigid material, milled or sawn flat ** Plank (wood) ** Cutting board ** Sounding board, of a musical instrument * Cardboard (paper product) * Paperboard * Fiberboard ** Hardboard, a ...
. Ellen Calmas was a board member.


Funding

During the seven years after its founding in 1995, the institute received $8.5 million in state grants, but as it prepared to celebrate its 20th anniversary in 2014, state support had vanished and no help at all was granted in the state budget that year. Nor had it been granted in the 2010, 2011 or 2012 fiscal years. Speaking about the falloff in appropriations, Representative Randy Hunt of
Sandwich A sandwich is a Dish (food), dish typically consisting variously of meat, cheese, sauces, and vegetables used as a filling between slices of bread, or placed atop a slice of bread; or, more generally, any dish in which bread serves as a ''co ...
said, according to the ''Cape Cod Times,'' that "some people associated with Silent Spring hav
raised hackles
" Hunt was quoted as saying that Silent Spring "activists" had been known to "denigrate anyone who they don't feel is pushing for their cause as hard as they want." The ''Times'' quoted co-founder Cheryl Osimo as responding, "I understand perhaps my passion can be misunderstood as abrasive." She said the loss of funds was caused by a "difficult economy," resulting in an increased need for private donations.
Sylvia Connor of East Sandwich, a breast cancer survivor and Silent Spring volunteer, said . . . that she and other survivors feel strongly about continuing the work of the research institute. She said ... it was a "slap in the face" to see tate RepresentativeBrian Mannal join forces with actor
Mark Ruffalo Mark Alan Ruffalo (; born November 22, 1967) is an American actor. He began acting in the late 1980s and first gained recognition for his work in Kenneth Lonergan's play ''This Is Our Youth'' (1996) and drama film ''You Can Count on Me'' (2000) ...
on his Water Defense organization at a time when Silent Spring has been doing without state funds.


References


Further reading



Jeanne Rizzo and Julia Brody, "50 Years After Rachel Carson," ''The Huffington Post'', April 29, 2014

"Contaminants Pervasive In Cape Cod's Drinking Water Supply, Silent Spring Institute Finds," Water Online, September 18, 2013


External links

*
Records of Silent Spring Institute, 1970-2011: A Finding Aid.Schlesinger Library
Radcliffe Institute, Harvard University. {{authority control 1994 establishments in Massachusetts Breast cancer organizations Newton, Massachusetts Medical and health organizations based in Massachusetts Organizations established in 1994