Sclerotin is a component of the

cuticle A cuticle (), or cuticula, is any of a variety of tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Various types of "cuticle" are non- homologous, differing in their origin, structu ...

of various

Arthropoda Arthropods ( ) are invertebrates in the phylum Arthropoda. They possess an exoskeleton with a cuticle made of chitin, often mineralised with calcium carbonate, a body with differentiated ( metameric) segments, and paired jointed appendages. ...

, most familiarly

insect Insects (from Latin ') are Hexapoda, hexapod invertebrates of the class (biology), class Insecta. They are the largest group within the arthropod phylum. Insects have a chitinous exoskeleton, a three-part body (Insect morphology#Head, head, ...

s. It is formed by cross-linking members of particular classes of

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...

molecules, a biochemical process called

sclerotization Sclerotization is a biochemical process that produces the rigid shell of sclerotin that comprises an insect's chitinous exoskeleton. It is prominent in the thicker, armored parts of insects and arachnid Arachnids are arthropods in the Class (b ...

, a form of tanning in which quinones are enzymatically introduced into the cuticle, and react with terminal and lysine-related amino groups in the proteins to form strong links between the molecules.Chapman, R.F. (1969) ''The Insects: Structure and Function''. Elsevier, New York. Chapter 22.37 - "Expansion of the new cuticle is brought to an end by the onset of tanning" The resulting material greatly increases the rigidity of an insect's

chitin Chitin (carbon, C8hydrogen, H13oxygen, O5nitrogen, N)n ( ) is a long-chain polymer of N-Acetylglucosamine, ''N''-acetylglucosamine, an amide derivative of glucose. Chitin is the second most abundant polysaccharide in nature (behind only cell ...

ous exoskeleton, which is otherwise fairly soft. It is particularly prominent in the thicker, armoured parts of

and

arachnid Arachnids are arthropods in the Class (biology), class Arachnida () of the subphylum Chelicerata. Arachnida includes, among others, spiders, scorpions, ticks, mites, pseudoscorpions, opiliones, harvestmen, Solifugae, camel spiders, Amblypygi, wh ...

integument, such as in the biting mouthparts and

sclerite A sclerite (Greek language, Greek , ', meaning "hardness, hard") is a hardened body part. In various branches of biology the term is applied to various structures, but not as a rule to vertebrate anatomical features such as bones and teeth. Instea ...

s of scorpions and beetles. As it matures, freshly formed sclerotin becomes a hard, horn-like substance with a range of yellow-brown colors. As animals adapted to life on land, increasingly diverse needs for organic stiffening components arose (as opposed to mineral stiffening components such as calcium carbonates and phosphates). Among the invertebrates, this need was met largely by the development of sclerotins and other cross-linked proteins that allowed insects to adapt to existence on the land and later to develop wings. Sclerotin is biochemically variable; different species incorporate different proteins in different proportions, and the same insect will use different compositions in forming the different components of its body. For example, a caterpillar may have sclerotized jaws, head capsule, and legs, with the rest of the body soft and membranous. In general, sclerotized cuticle is formed by cross-linking the various protein molecules with phenolic compounds – a tanning process under enzymatic control. In some of the

Apterygota The name Apterygota is sometimes applied to a former Subclass (biology), subclass of small, agile insects, distinguished from other insects by their lack of wings in the present and in their evolutionary history; notable examples are the silverfis ...

, however, at least some of the cross-linking is by disulphide bonds reminiscent of protein cross-linking in the formation of

keratin Keratin () is one of a family of structural fibrous proteins also known as ''scleroproteins''. It is the key structural material making up Scale (anatomy), scales, hair, Nail (anatomy), nails, feathers, horn (anatomy), horns, claws, Hoof, hoove ...

. This has led many authors to refer to such cross-linked proteins in invertebrates as keratin, but modern analyses have shown that the term is inappropriate: keratins are a fairly well-defined set of proteins comprising particular chains in different proportions cross-linked in particular ways. Invertebrate connective tissue proteins based on disulphide links appear to be radically different.BROWN, C. H.; Keratins in Invertebrates; Nature 166, 439 (9 September 1950); {{doi, 10.1038/166439a0

References

Structural proteins

See also

References