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Santa Jeremy Ono (; born November 23, 1962) is a Canadian-born American immunologist. He served in a variety of roles, including as the 15th president of the
University of Michigan The University of Michigan (U-M, U of M, or Michigan) is a public university, public research university in Ann Arbor, Michigan, United States. Founded in 1817, it is the oldest institution of higher education in the state. The University of Mi ...
from October 2022 to May 2025, as the 15th president of the
University of British Columbia The University of British Columbia (UBC) is a Public university, public research university with campuses near University of British Columbia Vancouver, Vancouver and University of British Columbia Okanagan, Kelowna, in British Columbia, Canada ...
from 2016 to 2022, and as the 28th president of the
University of Cincinnati The University of Cincinnati (UC or Cincinnati, informally Cincy) is a public university, public research university in Cincinnati, Ohio, United States. It was founded in 1819 and had an enrollment of over 53,000 students in 2024, making it the ...
from 2012 to 2016. Ono was selected to serve as the president of the
University of Florida The University of Florida (Florida or UF) is a public university, public land-grant university, land-grant research university in Gainesville, Florida, United States. It is a senior member of the State University System of Florida and a preem ...
in May 2025, but was later rejected by the Florida Board of Governors for the position.


Early life and education

Born in 1962, Santa Ono is the son of mathematician Takashi Ono, who immigrated to the United States from Japan in the late 1950s. Ono was born in
Vancouver Vancouver is a major city in Western Canada, located in the Lower Mainland region of British Columbia. As the List of cities in British Columbia, most populous city in the province, the 2021 Canadian census recorded 662,248 people in the cit ...
,
British Columbia British Columbia is the westernmost Provinces and territories of Canada, province of Canada. Situated in the Pacific Northwest between the Pacific Ocean and the Rocky Mountains, the province has a diverse geography, with rugged landscapes that ...
, Canada, where his father worked as an assistant professor of mathematics at the University of British Columbia from 1961 to 1964. As a result, Ono acquired United States citizenship through his parents and Canadian citizenship through his place of birth. Ono was raised in
Philadelphia, Pennsylvania Philadelphia ( ), colloquially referred to as Philly, is the List of municipalities in Pennsylvania, most populous city in the U.S. state of Pennsylvania and the List of United States cities by population, sixth-most populous city in the Unit ...
, and
Towson, Maryland Towson () is an unincorporated community and a census-designated place in Baltimore County, Maryland, United States. The population was 59,533 in the 2020 census. It is the county seat of Baltimore County and the second-most populous unincorpo ...
, where his father worked as a faculty member at the
University of Pennsylvania The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of f ...
from 1964 to 1969 and at
Johns Hopkins University The Johns Hopkins University (often abbreviated as Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland, United States. Founded in 1876 based on the European research institution model, J ...
from 1969 to 2011, respectively. His older brother is Momoro Ono and his younger brother is
Ken Ono Ken Ono (born March 20, 1968) is an American mathematician with fields of study in number theory. He is the STEM Advisor to the Provost and the Marvin Rosenblum Professor of Mathematics at the University of Virginia. Early life and education Ono ...
. Ono received a
Bachelor of Arts A Bachelor of Arts (abbreviated B.A., BA, A.B. or AB; from the Latin ', ', or ') is the holder of a bachelor's degree awarded for an undergraduate program in the liberal arts, or, in some cases, other disciplines. A Bachelor of Arts deg ...
with a major in
biological sciences Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, origin, evolution, and distribution of ...
from the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
in 1984 and a
Doctor of Philosophy A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of Postgraduate education, graduate study and original resear ...
in
experimental medicine An experimental drug is a medicinal product (a drug or vaccine) that has not yet received approval from governmental regulatory authorities for routine use in human or veterinary medicine. A medicinal product may be approved for use in one diseas ...
from
McGill University McGill University (French: Université McGill) is an English-language public research university in Montreal, Quebec, Canada. Founded in 1821 by royal charter,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, ...
in Canada in 1991.


Career


Academic career

Ono's research reported that immune-related genes are more active in insulin-producing cells in the pancreas, which could affect
diabetes Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...
risk. His lab showed that specific DNA elements and transcription factors are key in regulating these immune genes. The lab also identified potential biomarkers for tracking
age-related macular degeneration Macular degeneration, also known as age-related macular degeneration (AMD or ARMD), is a medical condition which may result in blurred or no vision in the center of the visual field. Early on there are often no symptoms. Some people experien ...
and studied how HMGA protein mutations could lead to fat tumors and obesity in mice. While at University College London, Ono served as associate dean of students and as a member of the University College London Council. From 2006 to 2010, Ono served as senior vice provost for undergraduate education and academic affairs at
Emory University Emory University is a private university, private research university in Atlanta, Georgia, United States. It was founded in 1836 as Emory College by the Methodist Episcopal Church and named in honor of Methodist bishop John Emory. Its main campu ...
in
Atlanta, Georgia Atlanta ( ) is the List of capitals in the United States, capital and List of municipalities in Georgia (U.S. state), most populous city in the U.S. state of Georgia (U.S. state), Georgia. It is the county seat, seat of Fulton County, Georg ...
.


University of Cincinnati

In June 2010, Ono was named senior vice president for academic affairs and university provost at the University of Cincinnati, with oversight of budgets, personnel, and planning. In 2012, Ono was named the 28th president of the University of Cincinnati in Ohio, becoming the first Asian-American president of that university. U Square at the Loop, a $78 million mixed use development, was opened during his presidency. In January 2015, ''
Inside Higher Education ''Inside Higher Ed'' is an American online publication of news, opinion, resources, events and jobs in the higher education sphere. In 2022, Quad Partners, a private equity firm, sold it to Times Higher Education, itself owned by Inflexion Priva ...
'' named Ono as "the nation's most notable college president for 2015".


University of British Columbia

On June 15, 2016, Ono was named the 15th president and vice chancellor of the
University of British Columbia The University of British Columbia (UBC) is a Public university, public research university with campuses near University of British Columbia Vancouver, Vancouver and University of British Columbia Okanagan, Kelowna, in British Columbia, Canada ...
in Canada, effective August 15. He was re-appointed for a second five-year term on August 11, 2020. In February 2017, Ono reinstated John Furlong as keynote speaker for a university fundraiser despite allegations of Furlong's abuse of Indigenous children during his time as a teacher in a remote community. Furlong's participation sparked protests from UBC students and activists, including some of his alleged victims. This incident led to the resignation of the only Indigenous member of UBC's Sexual Assault Policy Committee. Ono's decision to reinvite Furlong followed reported pressure from wealthy donors. In July 2019,
Amazon Amazon most often refers to: * Amazon River, in South America * Amazon rainforest, a rainforest covering most of the Amazon basin * Amazon (company), an American multinational technology company * Amazons, a tribe of female warriors in Greek myth ...
announced plans to establish Canada's first "Cloud Innovation Centre" at UBC. The project proceeded without community consultation. Contract details were withheld until a student group obtained them through a freedom of information request. The documents showed that the Ono administration followed Amazon's directive to keep $3 million in funding confidential. In October 2019, at least six students were given medical attention for suspected drugging incidents at a fraternity party. Following this, a female professor faced online abuse after criticizing the fraternities involvement in
Remembrance Day Remembrance Day (also known as Poppy Day owing to the tradition of wearing a remembrance poppy) is a memorial day observed in Commonwealth of Nations, Commonwealth member states since the end of the First World War to honour armed forces me ...
ceremonies. However, the university administration, under the Ono presidency, responded and emphasized freedom of expression rather than condemning the harassment against the professor, affirming its "commitment to freedom of expression and academic freedom". During Ono's tenure, the university hosted multiple controversial speakers promoting white supremacist, Islamophobic, and neo-Nazi movements, often invited by student groups with extreme views. Ono inaccurately claimed equal community support for an anti-trans speaker event, leading to the Vancouver Pride Society's decision in July 2019 to ban UBC's participation in the Vancouver Pride Parade.


University of Michigan

On July 13, 2022, Ono was named as the 15th president of the
University of Michigan The University of Michigan (U-M, U of M, or Michigan) is a public university, public research university in Ann Arbor, Michigan, United States. Founded in 1817, it is the oldest institution of higher education in the state. The University of Mi ...
, with his term beginning on October 13, 2022. He became the first Japanese American to lead the university. In October 2023, Ono received a 4% raise in base salary, increasing it from US$975,000 to US$1,014,000 annually. Under the Ono presidency, the university conducted a renovation of the President's House, the official residence of the university president, from 2022 to 2023 at a cost of $11.5 million. During Ono's March 2023 address, he stated that DEI would be a major focus of his presidency. In January 2024, the university was reported to have 241 employees in the Diversity, Equity, and Inclusion (DEI) offices, with payroll costs totaling more than $30 million annually. On March 27, 2025, citing the Trump administration's executive order, Ono reversed his previous DEI policies and shut down the university's DEI programs and offices. On October 17, 2024, the university's
Board of Regents In the United States, a board often governs institutions of higher education, including private universities, state universities, and community colleges. In each US state, such boards may govern either the state university system, individual co ...
voted unanimously to extend Ono's contract by an additional eight years, through October 1, 2032. The extension also increased Ono's base salary to US$1.3 million per year, a 33% rise since he started his tenure two years before. On January 10, 2025, Ono shut down the University of Michigan's two-decade-long partnership with
Shanghai Jiao Tong University Shanghai Jiao Tong University (SJTU) is a public university in Shanghai, China. It is affiliated with the Ministry of Education of the People's Republic of China, Ministry of Education of China. The university is part of Project 211, Project 98 ...
in China since 2005, terminating the UM–SJTU Joint Institute as well as the dual-degree and study-abroad programs. On May 4, 2025, the day after giving a speech as the president on the University of Michigan's spring commencement, Ono announced through a campus email that he became the sole finalist for the presidency of the
University of Florida The University of Florida (Florida or UF) is a public university, public land-grant university, land-grant research university in Gainesville, Florida, United States. It is a senior member of the State University System of Florida and a preem ...
and decided to leave Michigan. His tenure as president at the University of Michigan was the shortest of all past presidents. On May 5, Rebekah Modrak, chair of the university's Faculty Senate, said that many professors had complained that Ono's campus emails seemed to have been written by ChatGPT. The University of Michigan Board of Regents appointed
Domenico Grasso Domenico Grasso (born 1955) is an American environmental engineer who has been serving as the interim President of the University of Michigan, president of the University of Michigan since May 8, 2025. Grasso graduated from the University of Mi ...
, the then-chancellor of the
University of Michigan–Dearborn The University of Michigan–Dearborn (UM-Dearborn) is a public university in Dearborn, Michigan, United States. Founded in 1959 with a gift from the Ford Motor Company, it was initially known as the Dearborn Center, operating as a remote branc ...
, as the university's interim president on May 8, 2025, effectively removing Ono from the office.


Response to labor union protest

On March 7, 2023, the Graduate Employees' Organization 3550, a labor union representing graduate student instructors at the university, disrupted the ceremonial procession during Ono's inauguration. On March 29, the majority of GEO 3550 members went on
strike Strike may refer to: People *Strike (surname) * Hobart Huson, author of several drug related books Physical confrontation or removal *Strike (attack), attack with an inanimate object or a part of the human body intended to cause harm * Airstrike, ...
, demanding a salary increase from $24,000 to $38,000. The university unsuccessfully sought an
injunction An injunction is an equitable remedy in the form of a special court order compelling a party to do or refrain from doing certain acts. It was developed by the English courts of equity but its origins go back to Roman law and the equitable rem ...
to suspend the strike. On April 20, GEO members confronted Ono at a restaurant in Ann Arbor and blocked his car from leaving. Two protesters were arrested. GEO later accused the university of invented false grades for students in classes taught by striking GEO members. The
Higher Learning Commission The Higher Learning Commission (HLC) is an institutional accreditor in the United States. It has historically accredited post-secondary education institutions in the central United States: Arizona, Arkansas, Colorado, Illinois, Indiana, Iowa ...
investigated and later dismissed those accusations. As the strike extended into the spring, Ono reduced his attendance at campus events and his social media activity. The strike ended on August 25, 2023, when the university and GEO reached an agreement.


Israeli–Palestinian conflict

On October 10, 2023, Santa Ono condemned Hamas terrorists through a university statement. On October 13 afternoon, around 300 University of Michigan students and community members protested outside the President's House, objecting to Ono's statement and criticizing Ono's views on Palestinian people, casualties, and forced displacement. Ono responded with an additional statement to the university community on the same day, reaffirming his stance. In November, 40 pro-Palestinian students were arrested during a sit-in demonstration outside Ono's office. In December, Ono canceled the central student government's voting on two resolutions related to the
Israeli–Palestinian conflict The Israeli–Palestinian conflict is an ongoing military and political conflict about Territory, land and self-determination within the territory of the former Mandatory Palestine. Key aspects of the conflict include the Israeli occupation ...
. On April 30, 2024, United States Representative
Virginia Foxx Virginia Ann Foxx ( Palmieri;Foxx, Virginia Ann
. ''Biographical Directory of ...
called Santa Ono to a congressional hearing scheduled for May 23 on "antisemitic college chaos". On May 21, Ono cited fire safety reasons and sent police to clear the pro-Palestinian encampment on The Diag in front of the Hatcher Graduate Library. The encampment was first set up on April 22 to protest for
divestment In finance and economics, divestment or divestiture is the reduction of some kind of asset for financial, ethical, or political objectives or sale of an existing business by a firm. A divestment is the opposite of an investment. Divestiture is a ...
from
Israel Israel, officially the State of Israel, is a country in West Asia. It Borders of Israel, shares borders with Lebanon to the north, Syria to the north-east, Jordan to the east, Egypt to the south-west, and the Mediterranean Sea to the west. Isr ...
. Four protesters were arrested. Afterward, the United States House Committee on Education and Workforce changed Ono's congressional testimony format to transcribed interviews instead of having him appear before the full congressional committee as initially expected.


University of Florida

On May 4, 2025, while serving as the 15th president of the University of Michigan, Ono became the solo finalist for the presidency post at the University of Florida. Ono was removed from the presidency of the University of Michigan on May 8. On May 27, the University of Florida Board of Trustees voted unanimously to select Ono as the incoming 14th president of the University of Florida, pending ratification from the Florida Board of Governors (the governing body of the
State University System of Florida The State University System of Florida (SUSF or SUS) is a system of twelve public universities in the U.S. state of Florida. As of 2018, over 341,000 students were enrolled in Florida's state universities. Together with the Florida College Sy ...
). On June 3, 2025, Ono's hire was rejected by the Florida Board of Governors in a 10–6 vote. This decision came after a three hour long meeting between the Board and Ono, which included discussions on Ono's support of "race-based hiring, holistic admissions, DEI and climate activism." His candidacy had been questioned by national conservatives including Christopher Rufo and Donald Trump Jr., the latter of whom referred to Ono as a "woke psycho" who "might be a perfect fit for a Communist school in California". While it was reported that many of the members of the board disagreed with each other over Ono's beliefs in these and other areas, some were "praising no's..shift towards conservative values."


Social engagement

On January 23, 2017, Ono was appointed chief advisor of the British Columbia Innovation Network and a member of the British Columbia Technology Council. Ono served on the Medical & Scientific Advisory Board of the Tear Film and Ocular Surface Society, as well as on the Medical Advisory Board and College of Experts of the Medical Research Council in the United Kingdom. He has been a member of the
Faculty of 1000 F1000 (formerly "Faculty of 1000") is an open research publisher for scientists, scholars, and clinical researchers. F1000 offers a different research evaluation service from standard academic journals by offering peer-review after, rather than ...
since 2003.Ono received an honorary doctorate degree from
Chiba University is a national university in the city of Chiba, Chiba, Chiba, Japan. It offers doctoral degrees in education as part of a coalition with Tokyo Gakugei University, Saitama University, and Yokohama National University. The university was formed in ...
in Japan in 2016 and an honorary
doctor of divinity A Doctor of Divinity (DD or DDiv; ) is the holder of an advanced academic degree in divinity (academic discipline), divinity (i.e., Christian theology and Christian ministry, ministry or other theologies. The term is more common in the Englis ...
from the
Vancouver School of Theology The Vancouver School of Theology is a Christian ecumenical divinity school located on the campus of and affiliated with the University of British Columbia. Faculty * Mari Joerstad, Dean, Professor of Hebrew Bible * Joni Sancken, Professor of H ...
of the University of British Columbia in 2020. In 2017, he received a Professional Achievement Award from the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
Alumni Association. Ono was elected as a fellow of the Canadian Academy of Health Sciences in 2017. He was elected as a member of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
in 2022.


Personal life

Santa Ono was named after Santaro, a Japanese folk story character. Ono, a practicing
Anglican Anglicanism, also known as Episcopalianism in some countries, is a Western Christianity, Western Christian tradition which developed from the practices, liturgy, and identity of the Church of England following the English Reformation, in the ...
, is a member of the Anglican Communion Science Commission and served as a lay Eucharistic minister. Ono met Gwendolyn "Wendy" Yip at McGill University in 1985; Yip was in her undergraduate senior year when Ono came to the university to complete his PhD work. The pair married in 1989 and have two daughters together. Wendy Yip received a Bachelor of Science with a major in immunology from McGill University in 1988 and a
Juris Doctor A Juris Doctor, Doctor of Jurisprudence, or Doctor of Law (JD) is a graduate-entry professional degree that primarily prepares individuals to practice law. In the United States and the Philippines, it is the only qualifying law degree. Other j ...
from
Boston University Boston University (BU) is a Private university, private research university in Boston, Massachusetts, United States. BU was founded in 1839 by a group of Boston Methodism, Methodists with its original campus in Newbury (town), Vermont, Newbur ...
in 1991. Her father is Gar Lam Yip (), a Chinese-Canadian professor of
electrical and computer engineering Electrical engineering is an engineering discipline concerned with the study, design, and application of equipment, devices, and systems that use electricity, electronics, and electromagnetism. It emerged as an identifiable occupation in the l ...
at McGill University, and her mother is Alice Chan-Yip (), a Chinese-Canadian
pediatrician Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, pediatrics covers many of their youth ...
based in Montreal and former board member with the Montreal Chinese Hospital.


References


External links

* {{DEFAULTSORT:Ono, Santa J. 20th-century American scientists 21st-century American scientists 20th-century Canadian scientists 21st-century Canadian scientists American immunologists Canadian immunologists American scientists of Asian descent Canadian scientists of Asian descent American academics of Japanese descent Canadian people of Japanese descent Canadian Anglicans Canadian university and college chief executives Presidents of the University of British Columbia Presidents of the University of Cincinnati Harvard University alumni Academic staff of the University of British Columbia Academics of University College London Harvard University faculty Johns Hopkins University faculty GSK plc people McGill University alumni People from Towson, Maryland Scientists from Baltimore Scientists from Philadelphia Scientists from Vancouver Towson High School alumni University of Chicago alumni Fellows of the Royal Society of Medicine Fellows of the Royal Society of Chemistry Fellows of the American Academy of Arts and Sciences Fellows of the American Association for the Advancement of Science Helen Hay Whitney Foundation fellows Phi Delta Theta members 1962 births Living people Members of the National Academy of Medicine