S9632 (FEMA 4774) is a food additive which acts as a positive
allosteric modulator
In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli. Some of them, like benzodiazepines or alcohol, function as psychoactive drugs. The site that a ...
of the
TAS1R2
T1R2 - Taste receptor type 1 member 2 is a protein that in humans is encoded by the ''TAS1R2'' gene.
The sweet taste receptor is predominantly formed as a dimer of T1R2 and T1R3 by which different organisms sense this taste. In songbirds, howeve ...
/
TAS1R3
Taste receptor type 1 member 3 is a protein that in humans is encoded by the ''TAS1R3'' gene. The ''TAS1R3'' gene encodes the human homolog of mouse Sac taste receptor, a major determinant of differences between sweet-sensitive and -insensitive m ...
heterodimer that is the primary
sweet taste receptor in humans. It is described as a flavour modifier, having little taste of its own but causing sweet flavours to taste sweeter and enhancing certain aspects of the flavour profile. It was approved for use in food in 2012 and is used in various countries including the United States, Japan, South Korea, and Mexico.
See also
*
S6821
S6821 is a food additive that acts as a potent and selective antagonist of the bitter taste
The gustatory system or sense of taste is the sensory system that is partially responsible for the perception of taste. Taste is the perception stimu ...
*
Miraculin
Miraculin is a taste modifier, a glycoprotein extracted from the fruit of '' Synsepalum dulcificum''. The berry, also known as the miracle fruit, was documented by explorer Chevalier des Marchais, who searched for many different fruits during ...
References
Food additives
Taste modifiers
Isopropylamino compounds
Carboxamides
Quinolines
Carboxylic acids
Amines
{{pharm-stub