Rockport Virus
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Rockport virus (RKPV) is a single-stranded, enveloped, negative-sense
RNA Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA). RNA and deoxyrib ...
orthohantavirus ''Orthohantavirus'' is a genus of viruses that includes all hantaviruses (family ''Hantaviridae'') that cause disease in humans. Orthohantaviruses, hereafter referred to as hantaviruses, are naturally found primarily in rodents. In general, each ...
.


Natural reservoir

Rockport virus was first isolated in archival tissues of four
Eastern mole The eastern mole or common mole (''Scalopus aquaticus'') is a medium-sized North American mole. It is the only species in the genus ''Scalopus''. It is found in forested and open areas with moist sandy soils in northern Mexico, the eastern U ...
s found in and around
Rockport, Texas Rockport is a city and county seat of Aransas County, Texas, United States. The population was 10,070 at the 2020 census. Rockport is adjacent to the town of Fulton, and many refer to the combined communities as "Rockport-Fulton"; however, Ro ...
.


Virology

Phylogenetic analysis shows Rockport virus clusters geographically with Andes virus (ANDV) and
Sin Nombre virus Sin Nombre virus (SNV) is the most common cause of hantavirus pulmonary syndrome (HPS) in North America. Sin Nombre virus is transmitted mainly by the western deer mouse (''Peromyscus sonoriensis''). In its natural reservoir, SNV causes an asymp ...
(SNV), both of which are carried by sigmodontine and
Neotominae The Neotominae are a subfamily of the family Cricetidae. They consist of four tribes, 16 genera, and many species of New World rats and mice, predominantly found in North America. Among them are the well-known deer mice, packrats, and grasshopp ...
rodents. It shares the same S and the L genomic-segment with
Puumala virus Puumala virus (PUUV) is the main cause of hemorrhagic fever with renal syndrome (HFRS) in Europe and Russia. Puumala virus is transmitted by the bank vole (''Clethrionomys glareolus''). In its natural reservoir, PUUV causes a persistent infectio ...
(PUUV), Tula virus (TULV), and Prospect Hill virus (PHV).Arai S., et al. Phylogenetically distinct hantaviruses in the masked shrew (Sorex cinereus) and dusky shrew (Sorex monticolus) in the United States. Am. J. Trop. Med. Hyg. 78:348–351.


See also

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Hantavirus pulmonary syndrome Hantavirus pulmonary syndrome (HPS), also called hantavirus cardiopulmonary syndrome (HCPS), is a severe respiratory disease caused by hantaviruses. The main features of illness are microvascular leakage and acute respiratory distress syndrome. S ...
*
1993 Four Corners hantavirus outbreak The 1993 Four Corners hantavirus outbreak was an outbreak of Orthohantavirus, hantavirus disease in the United States in the Four Corners region of Arizona, Colorado, and New Mexico. Hantaviruses that cause disease in humans are native to roden ...
*
Cross-species transmission Cross-species transmission (CST), also called interspecies transmission, host jump, or spillover, is the transmission of an infectious pathogen, such as a virus, between hosts belonging to different species. Once introduced into an individual o ...
*
Hantavirus hemorrhagic fever with renal syndrome Hantavirus hemorrhagic fever with renal syndrome (HFRS) is a hemorrhagic fever caused by hantaviruses. Symptoms usually occur 12–16 days after exposure to the virus and come in five distinct phases: febrile, hypotensive, low urine production (ol ...


References


External links


CDC's Hantavirus Technical Information Index page



Virus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae


{{Taxonbar, from=Q29002559 Hantaviridae Zoonotic viral diseases