Desmethylflunitrazepam (also known as norflunitrazepam, Ro05-4435 and fonazepam) is a

benzodiazepine Benzodiazepines (BZD, BDZ, BZs), colloquially known as "benzos", are a class of central nervous system (CNS) depressant, depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed t ...

that is a

metabolite In biochemistry, a metabolite is an intermediate or end product of metabolism. The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, c ...

flunitrazepam Flunitrazepam, sold under the brand name Rohypnol among others, is a benzodiazepine used to treat severe insomnia and assist with anesthesia. As with other hypnotics, flunitrazepam has been advised to be prescribed only for short-term use or by ...

and has been sold online as a

designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...

. It has an IC₅₀ value of 1.499 nM for the GABA_A receptor.

References

Designer drugs 2-Fluorophenyl compounds GABAA receptor positive allosteric modulators Glycine receptor antagonists Lactams Nitrobenzodiazepines {{sedative-stub

See also

References