Richard Lounsbery Award
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The Richard Lounsbery Award is given to American and French
scientist A scientist is a person who Scientific method, researches to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engag ...
s, 45 years or younger, in recognition of "extraordinary scientific achievement in
biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...
and
medicine Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
." The Award alternates between French and American scientists, and is awarded by the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
and the
French Academy of Sciences The French Academy of Sciences (, ) is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific method, scientific research. It was at the forefron ...
in alternating years to a scientist from the other country. The award is selected by a seven-member jury representing both the French and the US Academies. The recipient receives a $75,000 prize, funding to visit a lab or research institution in the awarding country, and an invitation to give the Lounsbery Lecture in the awarding country. The Lounsbery Award was established in 1979 by Vera Lounsbery in memory of her husband, Richard Lounsbery, and is funded by the Richard Lounsbery Foundation. Richard and Vera met in Paris after
World War I World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
, and the couple divided their time between
Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...
and
New York New York most commonly refers to: * New York (state), a state in the northeastern United States * New York City, the most populous city in the United States, located in the state of New York New York may also refer to: Places United Kingdom * ...
.


Award recipients

Source: *2025 Michael M. Yartsev for pivotal contributions advancing our understanding of systems neuroscience. *202
Jean-Léon Maître
for outstanding and innovative work in mammalian developmental biology. *2023 Michelle Monje, for her groundbreaking discoveries that neuronal activity promotes adaptive myelination important for cognition, and that neuronal activity drives malignant glioma progression through neuron-to-glioma synapses and paracrine factors. These contributions have elucidated new perspectives in neuroscience and pioneered the field of cancer neuroscience. *2022 Claire Wyart, for her outstanding research on the sensory interface between the central nervous system and cerebrospinal fluid that controls our posture and movements. *2021
Feng Zhang Feng Zhang (; born October 22, 1981) is a Chinese-born American biochemist. Zhang currently holds the James and Patricia Poitras Professorship in Neuroscience at the McGovern Institute for Brain Research and in the Departments of Brain and Co ...
, for his pioneering achievements in the field of genome editing, including the discovery of novel CRISPR systems and their development as molecular tools. *2020 , for her work in developmental biology, in particular training and evolution of periodic patterns on the plumage of birds. *2019 Jay Shendure, for his pioneering work and leadership in the second wave of genomics that is transforming genetics and medicine. Through his development of exome sequencing and other novel technologies, he has defined new paradigms for implicating Mendelian disease genes, interpreting genetic variation, and single cell profiling of developmental lineages and gene regulation in whole organisms. *2018 , For his work on the genetic and mechanical regulation that underlies tissue proliferation, homeostasis and repair in physiological and pathological conditions (using a combination of interdisciplinary approaches involving sophisticated imaging, genetics, large-scale molecular approaches, and computational analyses) including the mechanisms of local and long-range mechano-sensing during cytokinesis that remodel the dividing cell adherens junction. *2017 Pardis Sabeti, for her contributions to global health and study of emerging diseases and
pandemics A pandemic ( ) is an epidemic of an infectious disease that has a sudden increase in cases and spreads across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. Widespread endemic dis ...
, including
ebola Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after in ...
,
Lassa fever Lassa fever, also known as Lassa hemorrhagic fever, is a type of viral hemorrhagic fever caused by the Lassa virus. Many of those infected by the virus asymptomatic, do not develop symptoms. When symptoms occur they typically include fever, wea ...
, and
malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
*2016 , for his work in Structural Biology (by X-ray diffraction and cryo-electron microscopy methods) on the regulation of gene expression at both the transcriptional level (structures of the nuclear receptors to retinoic acid and vitamin D) and the protein translation level (initiation and termination complexes, and the structure of the human ribosome). *2015
Hopi Hoekstra Danielle "Hopi" Elisabeth Hoekstra (born 1972) is an evolutionary biologist working at Harvard University in Cambridge, Massachusetts, where she is Dean of the Harvard Faculty of Arts and Sciences. Her lab uses natural populations of rodents to s ...
, for her work probing the molecular basis of how adaptation to novel selective pressures establishes and sustains diversity during
evolution Evolution is the change in the heritable Phenotypic trait, characteristics of biological populations over successive generations. It occurs when evolutionary processes such as natural selection and genetic drift act on genetic variation, re ...
. *2014 , for his major contributions to the understanding of molecular and cellular mechanisms causing
Huntington's disease Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly Genetic disorder#Autosomal dominant, inherited. It typically presents as a triad of progressive psychiatric, cognitive, and ...
. *2013
Karl Deisseroth Karl Alexander Deisseroth (born November 18, 1971) is an American scientist. He is the Chen Din Hwa, D.H. Chen Foundation Professor of Bioengineering and of psychiatry and Behavioural sciences, behavioral sciences at Stanford University. He is ...
, for pioneering the technology called
optogenetics Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by Gene expression, expression of Channelrhodopsin, light-sensitive ion channels, Halorhodopsin, pumps or Photoactivated ade ...
in which insertion of a single
bacterial Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the ...
protein into a
neuron A neuron (American English), neurone (British English), or nerve cell, is an membrane potential#Cell excitability, excitable cell (biology), cell that fires electric signals called action potentials across a neural network (biology), neural net ...
allows exquisite control of the neuron with light. *2012 , for his work in embryonic patterning in
vertebrates Vertebrates () are animals with a vertebral column (backbone or spine), and a cranium, or skull. The vertebral column surrounds and protects the spinal cord, while the cranium protects the brain. The vertebrates make up the subphylum Vertebra ...
and particularly in the genetic and developmental mechanisms that control segmentation. *2011 Bonnie L. Bassler, for her pioneering discoveries of the universal use of chemical communication among bacteria and the elucidation of structural and regulatory mechanisms controlling bacterial assemblies. *2010 Gérard Karsenty, for his work on the molecular mechanisms that underlie the formation and the remodeling of bone. *2009 Cornelia I. Bargmann, for her extraordinarily inventive and successful use of molecular and classical genetics to probe the individual nerve cell basis of behavior in
C. elegans ''Caenorhabditis elegans'' () is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek ''caeno-'' (recent), ''rhabditis'' ( ...
. *2008 , for his contributions to the understanding the genetic basis of the predisposition to viral and bacterial diseases of childhood, which have important clinical implications for the diagnostic and management of infectious diseases. *2007 Xiaodong Wang, for his pioneering biochemical studies on
apoptosis Apoptosis (from ) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. Biochemistry, Biochemical events lead to characteristic cell changes (Morphology (biol ...
, which have elucidated a molecular pathway leading into and out of the
mitochondrion A mitochondrion () is an organelle found in the cell (biology), cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double lipid bilayer, membrane structure and use aerobic respiration to generate adenosine tri ...
and to the
nucleus Nucleus (: nuclei) is a Latin word for the seed inside a fruit. It most often refers to: *Atomic nucleus, the very dense central region of an atom *Cell nucleus, a central organelle of a eukaryotic cell, containing most of the cell's DNA Nucleu ...
. *2006 Catherine Dulac, for her major contributions in the perception and behavioral translation of
pheromones A pheromone () is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to affect the behavi ...
in mammals. *2005 John Kuriyan, for his critical role in revealing the structural mechanisms underlying processivity in
DNA Deoxyribonucleic acid (; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of al ...
replication and the regulation of
tyrosine kinases -Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a conditionally essential amino acid with a polar side group. The word "tyrosine" is ...
and their interacting target proteins. *2004 Brigitte Kieffer, for her pioneering work on the molecular neurobiology of opioid-controlled behaviors, the results of which have very important implications for the treatment of pain, drug abuse, and emotional disorders. *2003 Carol W. Greider, for her pioneering biochemical and genetic studies of
telomerase Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most euka ...
, the enzyme that maintains the ends of
chromosomes A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most importa ...
in
eukaryotic The eukaryotes ( ) constitute the Domain (biology), domain of Eukaryota or Eukarya, organisms whose Cell (biology), cells have a membrane-bound cell nucleus, nucleus. All animals, plants, Fungus, fungi, seaweeds, and many unicellular organisms ...
cells. *2002 Denis Le Bihan, for his work on the invention and development of nuclear
magnetic resonance imaging Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and ...
of brain diffusion and perfusion. The method he developed permits in vivo mapping of nerve fiber bundles and has multiple applications in both medical pathology and cognitive science fields. *2001
Elaine Fuchs Elaine V. Fuchs is an American cell biologist known for her work on the biology and molecular mechanisms of mammalian skin and skin diseases, who helped lead the modernization of dermatology. Fuchs pioneered reverse genetics approaches, whic ...
, for her fundamental insights into structure and function of
cytoskeletal The cytoskeleton is a complex, dynamic network of interlinking protein filaments present in the cytoplasm of all Cell (biology), cells, including those of bacteria and archaea. In eukaryotes, it extends from the cell nucleus to the cell membrane ...
proteins and the relation of these proteins to human genetic diseases. *2000
Miroslav Radman Miroslav Radman (born April 30, 1944) is a Croatian biologist. Biography Radman was born in Split, PR Croatia, Yugoslavia. From 1962–1967 he studied experimental biology, physical chemistry and molecular biology at the University of Zagreb an ...
, for his contribution to the discovery of the molecular mechanisms implicated in the replication and repair of DNA, in particular, the discovery of a key enzyme of the DNA repair mechanism. *1999 Elliot M. Meyerowitz, for his pioneering contributions to the molecular genetics of plant architecture, which have practical implications for agriculture. *1998 Pascale Cossart, for her fundamental discoveries in microbiology dealing with mechanisms of bacterial entry and intracellular host motility. *1997 James E. Rothman, for his dissection of the biochemical mechanisms by which proteins are transferred from one cellular compartment to another and to the outside world. These mechanisms are important in neurotransmission, tissue biogenesis, and hormonal secretion. *1996 Daniel Louvard and Jacques Pouysségur, for their contributions to the study of the regulation of
cell division Cell division is the process by which a parent cell (biology), cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome(s) before dividing. In eukar ...
and differentiation. *1995 Douglas A. Melton, for showing how cells and tissues differentiate during vertebrate development through studies on localized mRNAs in eggs and the genes that induce
mesoderm The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.Langman's Medical ...
and neural tissue. *1994 Jean Louis Mandel, for his work in human genetics and in particular for his discovery of the mutation of fragile X. This new type of mutation has now been found at the origin of the diseases. *1993 Stanley B. Prusiner and Bert Vogelstein, for their distinct and exciting discoveries about the pathogenesis of neurodegenerative and malignant diseases. This award is given as a celebration of the power of modern molecular medicine. *1992 Philippe Ascher and Henri Korn, for their discoveries of the mechanisms of synaptic transmission. Philippe Ascher furthered knowledge regarding the properties of glutamate receptors which play an important role in trials, and Henri Korn brought to light the elementary liberation of neurotransmitter in quanta form in the
central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity o ...
of vertebrates. *1991
Marc W. Kirschner Marc Wallace Kirschner (born February 28, 1945) is an American cell biologist and biochemist and the founding chair of the Department of Systems Biology at Harvard Medical School. He is known for major discoveries in cell and developmental biolog ...
, for elucidating key steps in the cell cycle, chromosome movement, cell cycle timing, nucleus breakdown and reformation, and microtubule control of cell polarity and
mitosis Mitosis () is a part of the cell cycle in eukaryote, eukaryotic cells in which replicated chromosomes are separated into two new Cell nucleus, nuclei. Cell division by mitosis is an equational division which gives rise to genetically identic ...
. *1991 Harold Weintraub, for elucidating a molecular mechanism by which a single regulatory gene can lead to a program of cell differentiation. *1990 Jean Rosa, for his contributions, which have opened a new road in the control of oxygen transport in the blood and the treatment of the first worldwide genetic plague, drepanocytosis. *1989
Richard Axel Richard Axel (born July 2, 1946) is an American molecular biologist and university professor in the Department of Neuroscience at Columbia University and investigator at the Howard Hughes Medical Institute. His work on the olfactory system won h ...
, for his discoveries elucidating gene structure in animal cells. *1988 François Cuzin, for his original contributions in the elucidation of the mechanisms involved in malignant cell transformation, in particular, demonstration of the necessary contribution of two oncogenes. *1987
Alfred G. Gilman Alfred Goodman Gilman (July 1, 1941 – December 23, 2015) was an American pharmacology, pharmacologist and biochemist. He and Martin Rodbell shared the 1994 Nobel Prize in Physiology or Medicine "for their discovery of G protein, G-proteins an ...
and
Martin Rodbell Martin Rodbell (December 1, 1925 – December 7, 1998) was an American biochemist and molecular endocrinologist who is best known for his discovery of G-proteins. He shared the 1994 Nobel Prize in Physiology or Medicine with Alfred G. Gilman for ...
, for their discoveries regarding the proteins and mechanisms that mediate cellular responses to the binding of ligands to cell surface receptors. *1986 André Capron and Jacques Glowinski, for their fundamental work, which has contributed to the treatment of parasitic and neurological diseases. *1985 Martin Gellert and
Thomas Maniatis Tom Maniatis (born May 8, 1943), is an American professor of molecular and cellular biology. He is a professor at Columbia University, and serves as the Scientific Director and CEO of the New York Genome Center. Education Maniatis received B.A ...
, for their seminal contributions to our understanding of the structure and function of DNA, which were essential and fundamental to the development of recombinant DNA techniques. *1984 Maxime Schwartz, for his genetic and biochemical analysis of the maltose system of
E.Coli ''Escherichia coli'' ( )Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. is a gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly foun ...
, which paved the way for the solution of a series of fundamental problems in molecular biology. *1983
Günter Blobel Günter Blobel (; May 21, 1936 – February 18, 2018) was a Silesian German and American biologist and 1999 Nobel Prize laureate in Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in ...
, for his work in uncovering the molecular interactions that control the traffic of newly synthesized proteins in eukaryotic cells, for his incisive experiments, and for the beauty of the findings by which he established these interactions. *1982 Pierre Chambon and
Jean-Pierre Changeux Jean-Pierre Changeux (; born 6 April 1936) is a French neuroscientist known for his research in several fields of biology, from the structure and function of proteins (with a focus on the allosteric proteins), to the early development of the ner ...
, for their work on fundamental structures of genetic material and of the nervous system. *1981
Philip Leder Philip Leder (November 19, 1934 – February 2, 2020) was an American geneticist. Early life and education Leder was born in Washington, D.C., and studied at Harvard University, graduating in 1956. In 1960, he graduated from Harvard Medical Sch ...
, for his series of notable contributions in molecular genetics, which help to explain the means by which genetic information is organized and used to direct the synthesis of specific cell products. *1980 , for his work on the physiology of the
kidney In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organ (anatomy), organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and rig ...
. *1979
Michael S. Brown Michael Stuart Brown ForMemRS NAS AAA&S APS (born April 13, 1941) is an American geneticist and Nobel laureate. He was awarded the Nobel Prize in Physiology or Medicine with Joseph L. Goldstein in 1985 for describing the regulation of choles ...
and
Joseph L. Goldstein Joseph Leonard Goldstein ForMemRS (born April 18, 1940) is an American biochemist. He received the Nobel Prize in Physiology or Medicine in 1985, along with fellow University of Texas Southwestern researcher, Michael Brown, for their studies r ...
, for their work in
cholesterol Cholesterol is the principal sterol of all higher animals, distributed in body Tissue (biology), tissues, especially the brain and spinal cord, and in Animal fat, animal fats and oils. Cholesterol is biosynthesis, biosynthesized by all anima ...
biosynthesis.


See also

* List of biomedical science awards


References


External links

* See als
Other NAS Awards


from the Richard Lounsbery Foundation {{National Academy of Sciences, state= collapsed Awards established in 1979 Biomedical awards French Academy of Sciences French awards Awards of the United States National Academy of Sciences 1979 establishments in France 1979 establishments in Washington, D.C. American science and technology awards France–United States relations