Ribulose-5-phosphate
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Ribulose 5-phosphate is one of the end-products of the
pentose phosphate pathway The pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt or HMP shunt) is a metabolic pathway parallel to glycolysis. It generates NADPH and pentoses (five-carbon sugars) as well as ribose 5-ph ...
. It is also an intermediate in the
Calvin cycle The Calvin cycle, light-independent reactions, bio synthetic phase, dark reactions, or photosynthetic carbon reduction (PCR) cycle of photosynthesis is a series of chemical reactions that convert carbon dioxide and hydrogen-carrier compounds into ...
. It is formed by phosphogluconate dehydrogenase in the pentose phosphate pathway. Ribulose 5-phosphate is involved in various metabolic pathways. Ribulose 5-phosphate can be acted upon by phosphopentose isomerase to form
ribose 5-phosphate Ribose 5-phosphate (R5P) is both a product and an intermediate of the pentose phosphate pathway. The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate. Depending on the body's state, ...
, which is a precursor for nucleotide and co-factor biosynthesis. Ribulose-5 phosphate can also be acted upon by phosphopentose epimerase to form xylulose 5-phosphate, which is used in the nonoxidative phase of the pentose phosphate pathway in humans to generate precursor molecules for the synthesis of aromatic amino acids and production of energy. In plants, ribulose 5-phosphate produced from the pentose-phosphate pathway is converted into ribulose-1,5-bisphosphate by the enzyme phosphoribokinase.


See also

* Ribulose * Ribulose-1,5-bisphosphate


References

{{Pentose phosphate pathway intermediates Organophosphates Pentose phosphate pathway Monosaccharide derivatives