Receptor tyrosine phosphatases are

enzyme-linked receptor An enzyme-linked receptor, also known as a catalytic receptor, is a transmembrane receptor, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side. Hence a catalytic receptor is an integral membrane prote ...

phosphatase In biochemistry, a phosphatase is an enzyme that uses water to cleave a phosphoric acid Ester, monoester into a phosphate ion and an Alcohol (chemistry), alcohol. Because a phosphatase enzyme catalysis, catalyzes the hydrolysis of its Substrate ...

s, a family of

protein tyrosine phosphatases Protein tyrosine phosphatases (EC 3.1.3.48, systematic name protein-tyrosine-phosphate phosphohydrolase) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins: : proteintyrosine phosphate + H2O ...

. In humans, this family includes

PTPRA Receptor-type tyrosine-protein phosphatase alpha is an enzyme that in humans is encoded by the ''PTPRA'' gene. Function The protein encoded by this gene is a member of the receptor tyrosine phosphatases (RTP), a family of protein tyrosine p ...

, PTPRB,

PTPRC Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the ''PTPRC'' gene. PTPRC is also known as CD45 antigen (CD stands for cluster of differentiation), which was originally called leukocy ...

, PTPRD, PTPRE, PTPRF, PTPRG, PTPRH,

PTPRJ Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the ''PTPRJ'' gene. Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signalin ...

, PTPRK, PTPRM,

PTPRN Receptor-type tyrosine-protein phosphatase-like N, also called "IA-2", is an enzyme that in humans is encoded by the ''PTPRN'' gene. Overview The IA-2 protein encoded by PTPRN gene is a member of the protein tyrosine phosphatase (PTP) family ...

, PTPRN2, PTPRO, PTPRQ, PTPRR, PTPRS,

PTPRT Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the ''PTPRT'' gene. PTPRT is also known as PTPrho, PTPρ and human accelerated region 9. The human accelerated regions are 49 regions of the human genome tha ...

, PTPRU, and PTPRZ phosphatases.

References

Transmembrane receptors Single-pass transmembrane proteins {{enzyme-stub