Raymond Lemieux
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Raymond Urgel Lemieux, CC, AOE, FRS (June 16, 1920 – July 22, 2000) was a
Canadian Canadians () are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of their being ''C ...
organic chemist Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain ...
, who pioneered many discoveries in the field of
chemistry Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
, his first and most famous being the
synthesis Synthesis or synthesize may refer to: Science Chemistry and biochemistry *Chemical synthesis, the execution of chemical reactions to form a more complex molecule from chemical precursors **Organic synthesis, the chemical synthesis of organi ...
of
sucrose Sucrose, a disaccharide, is a sugar composed of glucose and fructose subunits. It is produced naturally in plants and is the main constituent of white sugar. It has the molecular formula . For human consumption, sucrose is extracted and refined ...
. His contributions include the discovery of the anomeric effect and the development of general methodologies for the synthesis of saccharides still employed in the area of carbohydrate chemistry. He was a fellow of the
Royal Society of Canada The Royal Society of Canada (RSC; , SRC), also known as the Academies of Arts, Humanities, and Sciences of Canada (French: ''Académies des arts, des lettres et des sciences du Canada''), is the senior national, bilingual council of distinguishe ...
and the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
(England), and a recipient of the prestigious
Albert Einstein World Award of Science The Albert Einstein World Award for Science is an annual award given by the World Cultural Council "as a means of recognition and encouragement for scientific and technological research and development", with special consideration for researche ...
and
Wolf Prize The Wolf Prize is an international award granted in Israel, that has been presented most years since 1978 to living scientists and artists for "achievements in the interest of mankind and friendly relations among people ... irrespective of natio ...
in Chemistry.


Life and career

''Dr. Raymond U. Lemieux'' was born in
Lac La Biche, Alberta Lac La Biche ( ) is an List of communities in Alberta#Urban service areas, urban service area in Lac La Biche County within Northern Alberta, northeastern Alberta, Canada. It is approximately northeast of the provincial capital, Edmonton. Pre ...
, Canada. His family moved to
Edmonton Edmonton is the capital city of the Provinces and territories of Canada, Canadian province of Alberta. It is situated on the North Saskatchewan River and is the centre of the Edmonton Metropolitan Region, which is surrounded by Central Alberta ...
,
Alberta Alberta is a Provinces and territories of Canada, province in Canada. It is a part of Western Canada and is one of the three Canadian Prairies, prairie provinces. Alberta is bordered by British Columbia to its west, Saskatchewan to its east, t ...
in 1926. He studied chemistry at the
University of Alberta The University of Alberta (also known as U of A or UAlberta, ) is a public research university located in Edmonton, Alberta, Canada. It was founded in 1908 by Alexander Cameron Rutherford, the first premier of Alberta, and Henry Marshall Tory, t ...
and received a BSc with Honours in Chemistry in 1943. He went on to study at
McGill University McGill University (French: Université McGill) is an English-language public research university in Montreal, Quebec, Canada. Founded in 1821 by royal charter,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, ...
, where he received his PhD in
Organic Chemistry Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain ...
in 1946. He won a post-doctoral
scholarship A scholarship is a form of Student financial aid, financial aid awarded to students for further education. Generally, scholarships are awarded based on a set of criteria such as academic merit, Multiculturalism, diversity and inclusion, athleti ...
at
Ohio State University The Ohio State University (Ohio State or OSU) is a public university, public Land-grant university, land-grant research university in Columbus, Ohio, United States. A member of the University System of Ohio, it was founded in 1870. It is one ...
, where Bristol Laboratories Inc. sponsored his research on the structure of
streptomycin Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, Mycobacterium avium complex, ''Mycobacterium avium'' complex, endocarditis, brucellosis, Burkholderia infection, ''Burkholderia'' i ...
. He met his future wife, a doctoral student, at Ohio State and they were married in 1948. In following years, he returned to Canada where he spent two years as an
assistant professor Assistant professor is an academic rank just below the rank of an associate professor used in universities or colleges, mainly in the United States, Canada, Japan, and South Korea. Overview This position is generally taken after earning a doct ...
at the
University of Saskatchewan The University of Saskatchewan (U of S, or USask) is a Universities in Canada, Canadian public university, public research university, founded on March 19, 1907, and located on the east side of the South Saskatchewan River in Saskatoon, Saskatch ...
. Next he served as Senior Research Officer at the National Research Council's Prairie Regional Laboratory in
Saskatoon Saskatoon () is the largest city in the Provinces and territories of Canada, Canadian province of Saskatchewan. It straddles a bend in the South Saskatchewan River in the central region of the province. It is located along the Trans-Canada Hig ...
. In 1953 he and a fellow researcher, George Huber, were the first scientists to successfully synthesize
sucrose Sucrose, a disaccharide, is a sugar composed of glucose and fructose subunits. It is produced naturally in plants and is the main constituent of white sugar. It has the molecular formula . For human consumption, sucrose is extracted and refined ...
. In 1954, he accepted the position of Dean in the Faculty of Pure and Applied Sciences at the
University of Ottawa The University of Ottawa (), often referred to as uOttawa or U of O, is a Official bilingualism in Canada, bilingual public research university in Ottawa, Ontario, Canada. The main campus is located on directly to the northeast of Downtown Ot ...
, where he established their Department of Chemistry. In 1961 he returned to the University of Alberta as a professor in the Chemistry Department and to serve as the chairman of the Organic Chemistry Division. He developed a method to make synthetic versions of
oligosaccharides An oligosaccharide (; ) is a saccharide polymer containing a small number (typically three to ten) of monosaccharides (simple sugars). Oligosaccharides can have many functions including cell recognition and cell adhesion. They are normally presen ...
, which led to improved treatments for
leukemia Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' ...
and
hemophilia Haemophilia (British English), or hemophilia (American English) (), is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a long ...
and the development of new
antibiotics An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ...
, blood reagents, and organ anti-rejection drugs. While at the University of Alberta, he established a number of biochemical companies, including R&L Molecular Research Ltd. in 1962, Raylo Chemicals Ltd. in 1966 (which purchased R&L) and Chembiomed in 1977 (which has since been taken over by Synsorb Biotech of
Calgary Calgary () is a major city in the Canadian province of Alberta. As of 2021, the city proper had a population of 1,306,784 and a metropolitan population of 1,481,806 making it the third-largest city and fifth-largest metropolitan area in C ...
, Alberta.) Prof. Lemieux published an autobiography, entitled "''Explorations with Sugars: How Sweet It Was''," in 1990. Dr. Raymond Lemieux died of an aneurysm in 2000. In 1999, the
University of Alberta The University of Alberta (also known as U of A or UAlberta, ) is a public research university located in Edmonton, Alberta, Canada. It was founded in 1908 by Alexander Cameron Rutherford, the first premier of Alberta, and Henry Marshall Tory, t ...
Faculty of Science and
Strathcona County Strathcona County is a Specialized municipalities of Alberta, specialized municipality in the Edmonton Metropolitan Region within Alberta, Canada between Edmonton and Elk Island National Park. It forms part of Division No. 11, Alberta, Census Di ...
established the Strathcona County/R.U. Lemieux Chair in Carbohydrate Chemistry. In 2001, the University of Alberta renamed the building(s) housing the Department of Chemistry to the Gunning/Lemieux Chemistry Centre to acknowledge the contributions of Profs. Raymond Lemieux and Harry Gunning.


Awards

Dr. R.U. Lemieux received numerous awards and honours for his work in chemistry: * Induction into the Royal Society of Canada (1954) * C.S. Hudson Award of the American Chemical Society (1966) * Became the first western Canadian to be elected a fellow of the Royal Society (England) (1967) * Appointed Officer of the
Order of Canada The Order of Canada () is a Canadian state order, national order and the second-highest Award, honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the Canadian Centennial, ce ...
(1968) * Haworth Award and Medal (1983) * The Tishler Award, Harvard University (1983) * Gairdner Foundation International Award (1985) * Made Honorary Doctor of Philosophy from the University of Stockholm (1988) * Induction into the Alberta Order of Excellence (1990) *
King Faisal International Prize The King Faisal Prize (, formerly King Faisal International Prize), is an annual award sponsored by King Faisal Foundation presented to "dedicated men and women whose contributions make a positive difference". The foundation awards prizes in fiv ...
for Science (first Canadian) (1990) * NSERC Gold Medal in Science (1991) *
Albert Einstein World Award of Science The Albert Einstein World Award for Science is an annual award given by the World Cultural Council "as a means of recognition and encouragement for scientific and technological research and development", with special consideration for researche ...
(1992) * Made Companion of the
Order of Canada The Order of Canada () is a Canadian state order, national order and the second-highest Award, honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the Canadian Centennial, ce ...
(1994) *
Wolf Prize The Wolf Prize is an international award granted in Israel, that has been presented most years since 1978 to living scientists and artists for "achievements in the interest of mankind and friendly relations among people ... irrespective of natio ...
in Chemistry (1999)


Notable former trainees

*''David R. Bundle'', former postdoctoral fellow with Prof. Lemieux, currently professor of chemistry, the Raymond U. Lemieux Chair in Carbohydrate Chemistry, and a distinguished university professor at the
University of Alberta The University of Alberta (also known as U of A or UAlberta, ) is a public research university located in Edmonton, Alberta, Canada. It was founded in 1908 by Alexander Cameron Rutherford, the first premier of Alberta, and Henry Marshall Tory, t ...
, founder and former director of the Alberta Glycomics Centre (formerly known as Alberta Ingenuity Centre for Carbohydrate Science). http://www.chem.ualberta.ca/~glyco/who/index.htm *''Ole Hindsgaul'', former PhD student with Prof. Lemieux, currently a distinguished professor at the
Carlsberg Laboratory The Carlsberg Research Laboratory is a private scientific research center in Copenhagen, Denmark under the Carlsberg Foundation. It was founded in 1875 by J. C. Jacobsen, the founder of the Carlsberg brewery, with the purpose of advancing bioche ...
, Copenhagen, Denmark, and an adjunct professor, Department of Chemistry,
University of Alberta The University of Alberta (also known as U of A or UAlberta, ) is a public research university located in Edmonton, Alberta, Canada. It was founded in 1908 by Alexander Cameron Rutherford, the first premier of Alberta, and Henry Marshall Tory, t ...
, Canada. http://www.crc.dk/carbochem/oledraft2.htm


Personal

Lemieux and Virginia (Jeannie) McConaghie met at
Ohio State University The Ohio State University (Ohio State or OSU) is a public university, public Land-grant university, land-grant research university in Columbus, Ohio, United States. A member of the University System of Ohio, it was founded in 1870. It is one ...
where Virginia was working towards her Ph.D. in Physical Chemistry. They married in New York City in 1948, upon her graduation. They had seven children; their daughter Janet was a Canadian champion soccer player; she was inducted into the Canada Soccer Hall of Fame in 2021.


See also

* Lemieux-Johnson oxidation * Anomeric effect * Carbohydrate chemistry


References


Further reading


The Alberta Order of Excellence Member ProfileScience.ca ProfileRemembering Dr. Lemieux (article)Order of Canada: Raymond U. Lemieux
{{DEFAULTSORT:Lemieux, Raymond 1920 births 2000 deaths Albert Einstein World Award of Science Laureates Canadian organic chemists Scientists from Edmonton Companions of the Order of Canada Members of the Alberta Order of Excellence People from Lac La Biche County University of Alberta alumni Academic staff of the University of Alberta Wolf Prize in Chemistry laureates Canadian fellows of the Royal Society McGill University Faculty of Science alumni Ohio State University fellows 20th-century Canadian chemists Canadian expatriates in the United States