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Randy Wayne Schekman (born December 30, 1948) is an American cell biologist at the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...
, former editor-in-chief of ''
Proceedings of the National Academy of Sciences ''Proceedings of the National Academy of Sciences of the United States of America'' (often abbreviated ''PNAS'' or ''PNAS USA'') is a peer-reviewed multidisciplinary scientific journal. It is the official journal of the National Academy of Sc ...
'' and former editor of '' Annual Review of Cell and Developmental Biology''. In 2011, he was announced as the editor of '' eLife'', a new high-profile
open-access journal Open access (OA) is a set of principles and a range of practices through which research outputs are distributed online, free of access charges or other barriers. With open access strictly defined (according to the 2001 definition), or libre o ...
published by the Howard Hughes Medical Institute, the
Max Planck Society The Max Planck Society for the Advancement of Science (german: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V.; abbreviated MPG) is a formally independent non-governmental and non-profit association of German research institutes. ...
and the
Wellcome Trust The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of Glax ...
launching in 2012. He was elected to the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
in 1992. Schekman shared the 2013 Nobel Prize for Physiology or Medicine with James Rothman and Thomas C. Südhof for their ground-breaking work on cell membrane vesicle trafficking.


Early life and education

Schekman was born in Saint Paul, Minnesota, to Alfred Schekman, an electrical engineer and computer software designer and Esther (Bader) Schekman. His family were Jewish emigrants from Russia and
Bessarabia Bessarabia (; Gagauz: ''Besarabiya''; Romanian: ''Basarabia''; Ukrainian: ''Бессара́бія'') is a historical region in Eastern Europe, bounded by the Dniester river on the east and the Prut river on the west. About two thirds of ...
. In the late 1950s his family moved to the new suburban community of Rossmoor, located in Orange County next to Long Beach. He graduated from
Western High School Western High School may refer: Schools in the United States * Western High School (Anaheim, California) – Anaheim, California *Western High School (Illinois) – Barry, Illinois *Western High School (Florida) – Davie, Florida *Western High Sch ...
in
Anaheim, California Anaheim ( ) is a city in northern Orange County, California, part of the Los Angeles metropolitan area. As of the 2020 United States Census, the city had a population of 346,824, making it the most populous city in Orange County, the 10th-most ...
, in 1966. He received a BA in Molecular Biology from the University of California in Los Angeles (UCLA), in 1971. He spent his third year at the
University of Edinburgh The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 15 ...
in Scotland, as an exchange student. He received a PhD in 1975 from Stanford University for research on
DNA replication In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part for biological inherita ...
working with Arthur Kornberg. After joining the faculty at University of California, Berkeley, he was promoted to Associate Professor in 1981 and Professor in 1984.


Research and career

Since 1991, Schekman has been a Howard Hughes Medical Institute Investigator, Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, at the University of California, Berkeley. The Schekman Lab at that university carries out research into molecular descriptions of the process of membrane assembly and vesicular traffic in
eukaryotic Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bact ...
cells including yeast. Before that, he was a faculty member with the now disbanded Department of Biochemistry at the same university.


Awards and honors

In 1987 Schekman received the Eli Lilly Award in Microbiology. In 1992, Schekman was elected a
Member of the National Academy of Sciences Membership of the National Academy of Sciences is an award granted to scientists that the National Academy of Sciences (NAS) of the United States judges to have made “distinguished and continuing achievements in original research”. Membership i ...
. In 2002, Schekman received the
Albert Lasker Award for Basic Medical Research The Albert Lasker Award for Basic Medical Research is one of the prizes awarded by the Lasker Foundation for a fundamental discovery that opens up a new area of biomedical science. The award frequently precedes a Nobel Prize in Medicine; almost ...
and
Louisa Gross Horwitz Prize The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemist ...
of
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manha ...
along with James Rothman for their discovery of cellular membrane trafficking, a process that cells use to organize their activities and communicate with their environment. In 2008 he was named the first Miller Senior Fellow of the Miller Institute at the University of California Berkeley. That same year, he was elected to the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communi ...
. He was awarded the Massry Prize from the
Keck School of Medicine The Keck School of Medicine of the University of Southern California teaches and trains physicians, biomedical scientists and other healthcare professionals, conducts medical research, and treats patients. Founded in 1885, it is the second oldest ...
,
University of Southern California , mottoeng = "Let whoever earns the palm bear it" , religious_affiliation = Nonsectarian—historically Methodist , established = , accreditation = WSCUC , type = Private research university , academic_affiliations = , endowment = $8. ...
, in 2010. Schekman serves as a member of the Selection Committee and then as chair of Life Science and Medicine which chooses winners of the
Shaw Prize The Shaw Prize is an annual award presented by the Shaw Prize Foundation. Established in 2002 in Hong Kong, it honours "individuals who are currently active in their respective fields and who have recently achieved distinguished and signifi ...
. Schekman was elected a Foreign Member of the Royal Society (ForMemRS) in 2013. His nomination reads: Schekman, Thomas C. Südhof, and James Rothman were awarded the 2013 Nobel Prize for Physiology or Medicine "for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells". Schekman donated his share of the prize money, $400,000, to create an endowment for the Esther and Wendy Schekman Chair in Basic Cancer Biology at UC Berkeley. Schekman's mother and sister, for whom the post is named, both died of cancer. In 2017, Schekman received the Golden Plate Award of the
American Academy of Achievement The American Academy of Achievement, colloquially known as the Academy of Achievement, is a non-profit educational organization that recognizes some of the highest achieving individuals in diverse fields and gives them the opportunity to meet o ...
.


Open-access science

In December 2013, Schekman called for academic journal publishing reform and
open access Open access (OA) is a set of principles and a range of practices through which research outputs are distributed online, free of access charges or other barriers. With open access strictly defined (according to the 2001 definition), or libre o ...
science publication by announcing that his lab at the University of California, Berkeley would no longer submit to the prestigious closed-access journals ''
Nature Nature, in the broadest sense, is the physical world or universe. "Nature" can refer to the phenomena of the physical world, and also to life in general. The study of nature is a large, if not the only, part of science. Although humans ar ...
'', '' Cell'', and ''
Science Science is a systematic endeavor that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earli ...
'', citing their self-serving and deleterious effects on science. He has criticized these journals for artificially restricting the number of publications accepted to drive up demand. In addition, Schekman says the journals accept papers that will be cited often, increasing the prestige of the journal, rather than those which demonstrate important results. Schekman has said the prestige and difficulty of publishing in these journals sometimes cause scientists to cut corners or pursue trends, rather than conduct research on important questions. Schekman is the former editor of '' eLife'', an
open access journal Open access (OA) is a set of principles and a range of practices through which research outputs are distributed online, free of access charges or other barriers. With open access strictly defined (according to the 2001 definition), or libre o ...
and competitor to ''Nature'', ''Cell'', and ''Science''. Papers are accepted into ''eLife'' based on review by working scientists. Access to accepted papers is free.


References


External links

* {{DEFAULTSORT:Schekman, Randy 1948 births Living people Nobel laureates in Physiology or Medicine American Nobel laureates American biochemists Foreign Members of the Royal Society Howard Hughes Medical Investigators Jewish American scientists Members of the United States National Academy of Sciences Recipients of the Albert Lasker Award for Basic Medical Research Alumni of the University of Edinburgh Stanford University alumni University of California, Berkeley College of Letters and Science faculty University of California, Los Angeles alumni Massry Prize recipients Open access activists Proceedings of the National Academy of Sciences of the United States of America editors