Psychotridine is an
alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids.
Alkaloids are produced by a large varie ...
found in some species of the genus ''
Psychotria
''Psychotria'' is a large genus of flowering plants in the coffee family Rubiaceae, with over 1,600 species. The genus has a pantropical distribution and members of the genus are small understorey trees in tropical forests. Some species are endan ...
'', namely ''
Psychotria colorata
''Psychotria colorata'' is a species of plant in the family Rubiaceae. It has been documented in an ethnobotanical context among the Ka'apor people of Maranhão, Brazil by Dr. William Balée, the Tulane University anthropologist
An anthropolo ...
'',
but also ''
Psychotria forsteriana'',
''
Psychotria lyciiflora'',
''
Psychotria oleoides'',
and ''
Psychotria beccarioides''.
Psychotridine has
analgesic
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in s ...
effects and dose-dependently inhibits
dizocilpine binding to cortical membranes ''in vitro'', suggesting that it acts as a
non-competitive NMDA receptor antagonist
NMDA receptor antagonists are a class of drugs that work to receptor antagonist, antagonize, or inhibit the action of, the NMDA, ''N''-Methyl-D-aspartate receptor (NMDA receptor, NMDAR). They are commonly used as anesthetics for humans and anima ...
.
See also
*
Hodgkinsine
References
Alkaloids
NMDA receptor antagonists
Pyrroloindoles
{{analgesic-stub