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Protected percutaneous coronary intervention, abbreviated as Protected PCI, is a heart procedure that involves a
ventricular assist device A ventricular assist device (VAD) is an electromechanical device for assisting cardiac circulation, which is used either to partially or to completely replace the function of a failing heart. The function of a VAD differs from that of an artific ...
that is used to treat patients with
cardiovascular disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, ...
, including advanced
heart failure Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome, a group of signs and symptoms caused by an impairment of the heart's blood pumping function. Symptoms typically include shortness of breath, excessive fatigue, ...
.


Procedure

During a protected percutaneous coronary intervention (Protected PCI) procedure, "the Impella 2.5 heart pump helps maintain a stable heart function by pumping blood for the heart. This gives a weak heart muscle an opportunity to rest and reduces the heart’s workload, preventing the heart from being overstressed by the procedure as coronary artery blockages are repaired". Deborah Moore, the Director of Interventional Cardiology at Florida Hospital Zephyrhills, stated that protected PCI is beneficial in patients who are "inoperable or non-candidates for
stent In medicine, a stent is a metal or plastic tube inserted into the lumen of an anatomic vessel or duct to keep the passageway open, and stenting is the placement of a stent. A wide variety of stents are used for different purposes, from expandab ...
s and
angioplasty Angioplasty, is also known as balloon angioplasty and percutaneous transluminal angioplasty (PTA), is a minimally invasive endovascular procedure used to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclero ...
." The Impella 2.5, used in protected PCI, "received FDA approval for elective and urgent high-risk PCI procedures in March 2015, following its 510(k) clearance in 2008" and as a percutaneous hemodynamic support device, it was deemed "safe and effective for patients with complex coronary disease, depressed ejection fraction, other co-morbidities, and who have been refused for surgical treatment." The PROTECT II Study, published in ''
Circulation Circulation may refer to: Science and technology * Atmospheric circulation, the large-scale movement of air * Circulation (physics), the path integral of the fluid velocity around a closed curve in a fluid flow field * Circulatory system, a bio ...
'' found that the "Impella 2.5 provided superior hemodynamic support in comparison with IABP, with maximal decrease in cardiac power output from baseline of −0.04±0.24 W in comparison with −0.14±0.27 W for IABP (''P''=0.001)." Hospitals such as
Detroit Medical Center The Detroit Medical Center (DMC) is a for-profit alliance of hospitals that encompasses over 2,000 licensed beds, 3,000 affiliated physicians and over 12,000 employees. Located in Midtown Detroit, the DMC is affiliated with medical schools from ...
, and organizations such as the Society of Cardiovascular Angiography and Interventions, have featured lectures including "The New Era of Protected PCI: Treating Elective and High-Risk PCI Patients with Impella 2.5", and "Expanding your Patient Practice with Protected PCI: Treating the Most Complex Patients" in order to educate physicians on using protected percutaneous coronary intervention, respectively.


See also

*
Intra-aortic balloon pump The intra-aortic balloon pump (IABP) is a mechanical device that increases myocardial oxygen perfusion and indirectly increases cardiac output through afterload reduction. It consists of a cylindrical polyurethane balloon that sits in the aor ...
*
Seldinger technique The Seldinger technique, also known as Seldinger wire technique, is a medical procedure to obtain safe access to blood vessels and other hollow organs. It is named after Sven Ivar Seldinger (1921–1998), a Swedish radiologist who introduced the ...
*
Impella Impella is a family of medical devices used for temporary ventricular support in patients with depressed heart function. Some versions of the device can provide left heart support during other forms of mechanical circulatory support including ECM ...
* Acute cardiac unloading


References


External links


Protected PCI
by
Abiomed Abiomed, Inc. is a medical device technology company that operates as a stand-alone business within Johnson & Johnson's MedTech Segment. Abiomed develops and manufactures temporary external and implantable mechanical circulatory support devices. ...

Understanding the Hemodynamics of Protected PCI - Martin B. Leon, MD and Dan Burkhoff, MD, PhD
by
Columbia University Medical Center NewYork-Presbyterian/Columbia University Irving Medical Center (NYP/CUIMC), also known as the Columbia University Irving Medical Center (CUIMC), is an academic medical center and the largest campus of NewYork-Presbyterian Hospital. It includes C ...

Building a Protected PCI Program: The Heart Team Approach
by
Einstein Medical Center Einstein Healthcare Network is a private non-profit healthcare organization based in the Philadelphia, Pennsylvania region of the United States. The healthcare network serves Greater Philadelphia and its flagship hospital is the Einstein Medical ...
{{Interventional cardiology Interventional cardiology Medical devices