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Damage
Damage is any change in a thing, often a physical object, that degrades it away from its initial state. It can broadly be defined as "changes introduced into a system that adversely affect its current or future performance".Farrar, C.R., Sohn, H., Park, G.,Converting Large Sensor Array Data into Structural Health Information, in Andrew Smyth, Raimondo Betti, ''The 4th International Workshop on Structural Control'' (2005), p. 67. Damage "does not necessarily imply total loss of system functionality, but rather that the system is no longer operating in its optimal manner". Damage to physical objects is "the progressive physical process by which they break",Jean Lemaitre, ''A Course on Damage Mechanics'' (2013). and includes mechanical stress that weakens a structure, even if this is not visible. Physical damage All physical damage begins on the atomic level, with the shifting or breaking of atomic bonds, and the rate at which damage to any physical thing occurs is therefore la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Damage (naturally Occurring)
Natural DNA damage is an alteration in the chemical structure of DNA, such as a break in a strand of DNA, a nucleobase missing from the backbone of DNA, or a chemically changed base such as 8-OHdG. DNA damage can occur naturally or via environmental factors, but is distinctly different from mutation, although both are types of error in DNA. DNA damage is an abnormal chemical structure in DNA, while a mutation is a change in the sequence of base pairs. DNA damages cause changes in the structure of the genetic material and prevents the replication mechanism from functioning and performing properly. The DNA damage response (DDR) is a complex signal transduction pathway which recognizes when DNA is damaged and initiates the cellular response to the damage. DNA damage and mutation have different biological consequences. While most DNA damages can undergo DNA repair, such repair is not 100% efficient. Un-repaired DNA damages accumulate in non-replicating cells, such as cells in the brai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Damage
Cell damage (also known as cell injury) is a variety of changes of stress that a cell suffers due to external as well as internal environmental changes. Amongst other causes, this can be due to physical, chemical, infectious, biological, nutritional or immunological factors. Cell damage can be reversible or irreversible. Depending on the extent of injury, the cellular response may be adaptive and where possible, homeostasis is restored. Cell death occurs when the severity of the injury exceeds the cell's ability to repair itself. Cell death is relative to both the length of exposure to a harmful stimulus and the severity of the damage caused. Cell death may occur by necrosis or apoptosis. Causes * Physical agents such as heat or radiation can damage a cell by literally cooking or coagulating their contents. * Impaired nutrient supply, such as lack of oxygen or glucose, or impaired production of adenosine triphosphate (ATP) may deprive the cell of essential materials needed to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Damage
Brain injury (BI) is the destruction or degeneration of brain cells. Brain injuries occur due to a wide range of internal and external factors. In general, brain damage refers to significant, undiscriminating trauma-induced damage. A common category with the greatest number of injuries is traumatic brain injury (TBI) following physical trauma or head injury from an outside source, and the term acquired brain injury (ABI) is used in appropriate circles to differentiate brain injuries occurring after birth from injury, from a genetic disorder (GBI), or from a congenital disorder (CBI). Primary and secondary brain injuries identify the processes involved, while focal and diffuse brain injury describe the severity and localization. Impaired function of affected areas can be compensated through neuroplasticity by forming new neural connections. Signs and symptoms Symptoms of brain injuries vary based on the severity of the injury or how much of the brain is affected. The fou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Damage Mechanics
Damage mechanics is concerned with the representation, or modeling, of damage of materials that is suitable for making engineering predictions about the initiation, propagation, and fracture of materials without resorting to a microscopic description that would be too complex for practical engineering analysis. Damage mechanics illustrates the typical engineering approach to model complex phenomena. To quote Dusan Krajcinovic, "It is often argued that the ultimate task of engineering research is to provide not so much a better insight into the examined phenomenon but to supply a rational predictive tool applicable in design." Damage mechanics is a topic of applied mechanics that relies heavily on continuum mechanics. Most of the work on damage mechanics uses state variables to represent the ''effects'' of damage on the stiffness and remaining life of the material that is damaging as a result of thermomechanical load and ageing. The state variables may be measurable, e.g., crack den ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ageing
Ageing (or aging in American English) is the process of becoming older until death. The term refers mainly to humans, many other animals, and fungi; whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species. In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes. Reaction time, for example, may slow with age, while memories and general knowledge typically increase. Of the roughly 150,000 people who die each day across the globe, about two-thirds die from age-related causes. Current ageing theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the programmed ageing concept, whereby the internal processes (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Water Damage
Water damage describes various possible losses caused by water intruding where it will enable attack of a material or system by destructive processes such as rotting of wood, mold growth, bacteria growth, rusting of steel, swelling of composite woods, damage to laminated materials like plywood, short-circuiting of electrical devices, etc. The damage may be very slow and minor such as water spots that could eventually mar a surface, or it may be instantaneous and catastrophic such as burst pipes and flooding. However fast it occurs, water damage is a major contributor to loss of property. An insurance policy may or may not cover the costs associated with water damage and the process of water damage restoration. While a common cause of residential water damage is often the failure of a sump pump, many homeowner's insurance policies do not cover the associated costs without an addendum which adds to the monthly premium of the policy. Often the verbiage of this addendum is simila ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collateral Damage
"Collateral damage" is a term for any incidental and undesired death, injury or other damage inflicted, especially on civilians, as the result of an activity. Originally coined to describe military operations, it is now also used in non-military contexts to refer to negative unintended consequences of an action. Since the development of precision-guided munitions in the 1970s, military forces often claim to have gone to great lengths to minimize collateral damage. Critics of use of the term "collateral damage" see it as a euphemism that dehumanizes non-combatants killed or injured during combat, used to reduce the perceived culpability of military leadership in failing to prevent non-combatant casualties. Collateral damage does not include civilian casualties caused by military operations that are intended to terrorize or kill enemy civilians (e.g., the bombing of Chongqing during World War II and Russian strikes against Ukrainian infrastructure openly described as "ret ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radiation Damage
Radiation damage is the effect of ionizing radiation on physical objects including non-living structural materials. It can be either detrimental or beneficial for materials. Radiobiology is the study of the action of ionizing radiation on living things, including the health effects of radiation in humans. High doses of ionizing radiation can cause damage to living tissue such as radiation burning and harmful mutations such as causing cells to become cancerous, and can lead to health problems such as radiation poisoning. Causes This radiation may take several forms: *Cosmic rays and subsequent energetic particles caused by their collision with the atmosphere and other materials. *Radioactive daughter products ( radioisotopes) caused by the collision of cosmic rays with the atmosphere and other materials, including living tissues. *Energetic particle beams from a particle accelerator. *Energetic particles or electro-magnetic radiation (X-rays) released from collisions of such par ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nerve Damage
Nerve injury is an injury to a nerve. There is no single classification system that can describe all the many variations of nerve injuries. In 1941, Herbert Seddon introduced a classification of nerve injuries based on three main types of nerve fiber injury and whether there is continuity of the nerve. Usually, however, nerve injuries are classified in five stages, based on the extent of damage to both the nerve and the surrounding connective tissue, since supporting glial cells may be involved. Unlike in the central nervous system, neuroregeneration in the peripheral nervous system is possible. The processes that occur in peripheral regeneration can be divided into the following major events: Wallerian degeneration, axon regeneration/growth, and reinnervation of nervous tissue. The events that occur in peripheral regeneration occur with respect to the axis of the nerve injury. The proximal stump refers to the end of the injured neuron that is still attached to the neuron cell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indirect DNA Damage
Indirect DNA damage occurs when a UV-photon is absorbed in the human skin by a chromophore that does not have the ability to convert the energy into harmless heat very quickly. Molecules that do not have this ability have a long-lived excited state. This long lifetime leads to a high probability for reactions with other molecules—so-called bimolecular reactions. Melanin and DNA have extremely short excited state lifetimes in the range of a few femtoseconds (10−15s). The excited state lifetime of compounds used in sunscreens such as menthyl anthranilate, avobenzone or padimate O is 1,000 to 1,000,000 times longer than that of melanin, and therefore they may cause damage to living cells that come in contact with them. The molecule that originally absorbs the UV-photon is called a "chromophore". Bimolecular reactions can occur either between the excited chromophore and DNA or between the excited chromophore and another species, to produce free radicals and reactive ox ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hurricane Ike Bridge City TX Shell Gas Station
A tropical cyclone is a rapidly rotating storm system with a low-pressure area, a closed low-level atmospheric circulation, strong winds, and a spiral arrangement of thunderstorms that produce heavy rain and squalls. Depending on its location and strength, a tropical cyclone is called a hurricane (), typhoon (), tropical storm, cyclonic storm, tropical depression, or simply cyclone. A hurricane is a strong tropical cyclone that occurs in the Atlantic Ocean or northeastern Pacific Ocean. A typhoon is the same thing which occurs in the northwestern Pacific Ocean. In the Indian Ocean and South Pacific, comparable storms are referred to as "tropical cyclones". In modern times, on average around 80 to 90 named tropical cyclones form each year around the world, over half of which develop hurricane-force winds of or more. Tropical cyclones typically form over large bodies of relatively warm water. They derive their energy through the evaporation of water from the ocean surface ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trauma (medicine)
Injury is physiological damage to the living tissue of any organism, whether in humans, in other animals, or in plants. Injuries can be caused in many ways, including mechanically with penetration by sharp objects such as teeth or with blunt objects, by heat or cold, or by venoms and biotoxins. Injury prompts an inflammatory response in many taxa of animals; this prompts wound healing. In both plants and animals, substances are often released to help to occlude the wound, limiting loss of fluids and the entry of pathogens such as bacteria. Many organisms secrete antimicrobial chemicals which limit wound infection; in addition, animals have a variety of immune responses for the same purpose. Both plants and animals have regrowth mechanisms which may result in complete or partial healing over the injury. Cells too can repair damage to a certain degree. Taxonomic range Animals Injury in animals is sometimes defined as mechanical damage to anatomical struct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
