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Semipermeable membrane is a type of
biological Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary in ...
or
synthetic Synthetic things are composed of multiple parts, often with the implication that they are artificial. In particular, 'synthetic' may refer to: Science * Synthetic chemical or compound, produced by the process of chemical synthesis * Synthetic o ...
, polymeric membrane that will allow certain molecules or ions to pass through it by osmosis. The rate of passage depends on the pressure, concentration, and temperature of the molecules or solutes on either side, as well as the permeability of the membrane to each solute. Depending on the membrane and the solute, permeability may depend on solute size, solubility, properties, or chemistry. How the membrane is constructed to be selective in its permeability will determine the rate and the permeability. Many natural and synthetic materials which are rather thick are also semipermeable. One example of this is the thin film on the inside of the egg. Biological membranes are selectively permeable, with the passage of molecules controlled by facilitated diffusion, passive transport or active transport regulated by proteins embedded in the membrane.


Biological membranes

An example of a biological semi-permeable membrane is the lipid bilayer, on which is based the
plasma membrane The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (t ...
that surrounds all biological cells. A group of phospholipids (consisting of a phosphate head and two fatty acid tails) arranged into a double layer, the phospholipid bilayer is a semipermeable membrane that is very specific in its permeability. The hydrophilic phosphate heads are in the outside layer and exposed to the water content outside and within the cell. The hydrophobic tails are the layer hidden in the inside of the membrane. The phospholipid bilayer is most permeable to small, uncharged solutes. Protein channels are embedded in or through phospholipids, and, collectively, this model is known as the fluid mosaic model. Aquaporins are protein channel pores permeable to water.


Cellular communication

Information can also pass through the plasma membrane when signaling molecules bind to receptors in the cell membrane. The signaling molecules bind to the receptors, which alters the structure of these proteins. A change in the protein structure initiates a signalling cascade; The G protein-coupled receptor signalling provides is an important subset of such signalling processes.


Reverse osmosis

The bulk flow of water through a selectively permeable membrane because of an
osmotic pressure Osmotic pressure is the minimum pressure which needs to be applied to a solution to prevent the inward flow of its pure solvent across a semipermeable membrane. It is also defined as the measure of the tendency of a solution to take in a pure ...
difference is called osmosis. This allows only certain particles to go through including water and leaving behind the solutes including salt and other contaminants. In the process of
reverse osmosis Reverse osmosis (RO) is a water purification process that uses a partially permeable membrane to separate ions, unwanted molecules and larger particles from drinking water. In reverse osmosis, an applied pressure is used to overcome osmotic pre ...
, water is purified by applying high pressure to a solution and thereby push water through a thin-film composite membrane (TFC or TFM). These are semipermeable membranes manufactured principally for use in water purification or
desalination Desalination is a process that takes away mineral components from saline water. More generally, desalination refers to the removal of salts and minerals from a target substance, as in Soil salinity control, soil desalination, which is an issue f ...
systems. They also have use in chemical applications such as batteries and fuel cells. In essence, a TFC material is a molecular sieve constructed in the form of a film from two or more layered materials. Sidney Loeb and Srinivasa Sourirajan invented the first practical synthetic semi-permeable membrane. Membranes used in reverse osmosis are, in general, made out of polyamide, chosen primarily for its permeability to water and relative impermeability to various dissolved impurities including salt ions and other small molecules that cannot be filtered. Another example of a semipermeable membrane is
dialysis tubing Dialysis tubing, also known as ''Visking tubing'', is an artificial semi-permeable membrane tubing90% of a protein having a molecular mass of at least 10 kDa. Pore sizes typically range from ~10–100 Angstroms for 1K to 50K MWCO membranes. It ...
.


Other types

Other types of semipermeable membranes are cation-exchange membranes (CEMs),
anion-exchange membrane An anion exchange membrane (AEM) is a semipermeable membrane generally made from ionomers and designed to conduct anions but reject gases such as oxygen or hydrogen. Applications Anion exchange membranes are used in electrolytic cells and fuel c ...
s (AEMs), alkali anion exchange membranes (AAEMs) and
proton-exchange membrane A proton-exchange membrane, or polymer-electrolyte membrane (PEM), is a semipermeable membrane generally made from ionomers and designed to conduct protons while acting as an electronic insulator and reactant barrier, e.g. to oxygen and hydrogen g ...
s (PEMs).


References


Further reading

* See this document for definitions of penetrant (permeant), synthetic (artificial) membrane, and anion-exchange membrane. * *


External links


The European Membrane House
a non-profit international association created to continue the work of the network and parternships developed in NanoMemPro, an earlier EU-funded European network of membrane researchers.
Short, non-scholarly WiseGeek article, "What is a Semipermeable Membrane.
{{Galvanic cells Diffusion Filters Membrane biology Membrane technology