PHCCC is a research drug which acts as a

glutamate receptor Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base of glutamic acid) is abundant in the human body, but particularly in the nervous system ...

ligand, particularly being a

positive allosteric modulator In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli. Some of them, like benzodiazepines or alcohol, function as psychoactive drugs. The site that ...

at the mGluR₄ subtype, as well as an agonist at mGluR₆. It has anxiolytic effects in animal studies. PHCCC and similar drugs have been suggested as novel treatments for

Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become ...

References

Cyclopropanes MGlu4 receptor agonists Ketoximes Anilides {{nervous-system-drug-stub

See also

References