Syndromic autism (or syndromic autism spectrum disorder) denotes cases of
autism spectrum disorder
Autism, also known as autism spectrum disorder (ASD), is a neurodevelopmental disorder characterized by differences or difficulties in social communication and interaction, a preference for predictability and routine, sensory processing di ...
that are associated with a broader
medical condition
A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical condi ...
, generally a
syndrome
A syndrome is a set of medical signs and symptoms which are correlated with each other and often associated with a particular disease or disorder. The word derives from the Greek language, Greek σύνδρομον, meaning "concurrence". When a sy ...
. Cases without such association, which account for the majority of total autism cases, are known as ''non-syndromic autism'' (or ''non-syndromic autism spectrum disorder'').
Studying the differences and similarities (e.g., common
pathways) between syndromic and non-syndromic cases can provide insights about the
pathophysiology of autism and pave the way to new