Nephroscope
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A nephroscopy is an
endoscopic An endoscopy is a procedure used in medicine to look inside the body. The endoscopy procedure uses an endoscope to examine the interior of a hollow organ or cavity of the body. Unlike many other medical imaging techniques, endoscopes are insert ...
examination of the
kidney In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organ (anatomy), organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and rig ...
. During the operation the surgeon passes a thin telescope (the
nephroscope A nephroscopy is an endoscopic examination of the kidney. During the operation the surgeon passes a thin telescope (the nephroscope) into the kidney's drainage tubes through a key-hole puncture in the skin, letting them see, break up and take ou ...
) into the kidney's drainage tubes through a key-hole puncture in the skin, letting them see, break up and take out
stones In geology, rock (or stone) is any naturally occurring solid mass or aggregate of minerals or mineraloid matter. It is categorized by the minerals included, its Chemical compound, chemical composition, and the way in which it is formed. Rocks ...
that are blocking urine.


History

The first reported attempt at percutaneous renal access was made by the London physician Thomas Hillier in 1865, when he repeatedly drained a hydronephrotic kidney in a child through the loin, hoping to create a permanent
fistula In anatomy, a fistula (: fistulas or fistulae ; from Latin ''fistula'', "tube, pipe") is an abnormal connection (i.e. tube) joining two hollow spaces (technically, two epithelialized surfaces), such as blood vessels, intestines, or other h ...
; the concept did not gain acceptance at the time. Modern practice dates from 1941, when Rupel and Brown slid a rigid
cystoscope Cystoscopy is endoscopy of the urinary bladder via the urethra. It is carried out with a cystoscope. The urethra is the tube that carries urine from the bladder to the outside of the body. The cystoscope has lenses like a telescope or microscop ...
through a surgically made tunnel into the kidney and took out a stone while watching it directly. In 1955 the radiologist Willard Goodwin performed the first radiologically guided antegrade nephrostogram and left a drainage tube ''
in situ is a Latin phrase meaning 'in place' or 'on site', derived from ' ('in') and ' ( ablative of ''situs'', ). The term typically refers to the examination or occurrence of a process within its original context, without relocation. The term is use ...
'', establishing the principle of the percutaneous nephrostomy. The first true percutaneous nephrolithotomy (PCNL)—extraction of a renal pelvic stone through a percutaneous tract under
fluoroscopic Fluoroscopy (), informally referred to as "fluoro", is an imaging technique that uses X-rays to obtain real-time moving images of the interior of an object. In its primary application of medical imaging, a fluoroscope () allows a surgeon to see t ...
control—was described by Fernström and Johansson in 1976, with further refinements by Alken, Marberger, Wickham and others during the late 1970s and early 1980s; in 1978 Arthur Smith coined the term endourology for these closed, image-guided interventions. Subsequent innovations such as telescopic tract dilators and the wide-bore Amplatz sheath reduced bleeding and improved visibility, establishing PCNL and nephroscopy as the standard
minimally invasive Minimally invasive procedures (also known as minimally invasive surgeries) encompass surgical techniques that limit the size of incisions needed, thereby reducing wound healing time, associated pain, and risk of infection. Surgery by definitio ...
approach for large or complex
renal stone Kidney stone disease (known as nephrolithiasis, renal calculus disease, or urolithiasis) is a crystallopathy and occurs when there are too many minerals in the urine and not enough liquid or hydration. This imbalance causes tiny pieces of cry ...
s.


Techniques and indications

The
European Association of Urology The European Association of Urology (EAU) is a non-profit organisation committed to the representation of urology professionals worldwide. All active urology professionals, including urology nurses, are eligible for membership of the EAU. The co ...
considers percutaneous nephroscopy, performed as part of PCNL, the first-line option for renal stones larger than and for complex staghorn calculi that are unlikely to clear with shock-wave
lithotripsy Lithotripsy is a procedure involving the physical destruction of hardened masses like kidney stones, bezoars or gallstones, which may be done non-invasively. The term is derived from the Greek words meaning "breaking (or pulverizing) stones" ( lit ...
or
ureteroscopy Ureteroscopy is an examination of the upper urinary tract, usually performed with a ureteroscope that is passed through the urethra and the bladder, and then directly into the ureter. The procedure is useful in the diagnosis and treatment of dis ...
. Surgeons usually keep the access tunnel open with a 24–30 F Amplatz sheath, but many units now prefer "mini-PCNL" tunnels (smaller than 18 F). The narrower track removes less kidney tissue and lowers bleeding, so recovery is quicker, though the operation can take a little longer. The smaller tract removes less kidney tissue and can shorten recovery, although the operation may take a little longer because the narrower channel limits the size of instruments and stone fragments that can be removed at one time. Modern scopes carry a tiny
CMOS camera Complementary metal–oxide–semiconductor (CMOS, pronounced "sea-moss ", , ) is a type of MOSFET, metal–oxide–semiconductor field-effect transistor (MOSFET) semiconductor device fabrication, fabrication process that uses complementary an ...
and two
LED light An LED lamp or LED light is an electric light that produces light using light-emitting diodes (LEDs). LED lamps are significantly more Electrical efficiency, energy-efficient than equivalent Incandescent light bulb, incandescent lamps and f ...
cords at their tip, giving high-definition pictures. Most designs (including mini-PCNL versions) also have a wide channel that provides continuous wash-in and suction, big enough to pass laser or
ultrasound Ultrasound is sound with frequency, frequencies greater than 20 Hertz, kilohertz. This frequency is the approximate upper audible hearing range, limit of human hearing in healthy young adults. The physical principles of acoustic waves apply ...
probes. This lets the surgeon see, break up and remove the stone through one instrument. Emerging adjuncts such as 3-D printed renal models,
augmented reality Augmented reality (AR), also known as mixed reality (MR), is a technology that overlays real-time 3D computer graphics, 3D-rendered computer graphics onto a portion of the real world through a display, such as a handheld device or head-mounted ...
puncture guidance and preliminary AI algorithms aim to lower vascular injury and reduce fluoroscopy exposure. Whatever equipment is used, the operation has three main stages. First, the surgeon punctures a kidney calyx under
X-ray An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ran ...
or ultrasound guidance. Next, they widen the track step by step and insert an Amplatz sheath to hold it open. Finally, they inspect the kidney, remove or powder the stone pieces, and—if bleeding control or
drainage Drainage is the natural or artificial removal of a surface's water and sub-surface water from an area with excess water. The internal drainage of most agricultural soils can prevent severe waterlogging (anaerobic conditions that harm root gro ...
needs it—leave a nephrostomy tube or
stent In medicine, a stent is a tube usually constructed of a metallic alloy or a polymer. It is inserted into the Lumen (anatomy), lumen (hollow space) of an anatomic vessel or duct to keep the passageway open. Stenting refers to the placement of ...
.


Complications

A
systematic review A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from published studies on ...
of nearly 12,000 PCNL cases reported
postoperative fever Postoperative fever refers to an elevated body temperature (≥ 38.5 °C) occurring after a recent surgical procedure. Diagnosing the cause of postoperative fever can sometimes be challenging; while fever in this context may be benign, self-li ...
in 10.8% of patients,
blood transfusion Blood transfusion is the process of transferring blood products into a person's Circulatory system, circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used ...
in 7% and procedure-related mortality of 0.05%. Bleeding, infection and other problems are likelier if several access tracks are used, if the drainage system is torn, or if the patient already has
anaemia Anemia (also spelt anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin availab ...
before surgery.


Post-operative care

Using several types of pain relief, choosing smaller tubes—or sometimes no tube at all—can cut hospital stay and reduce opioid use after PCNL.


References

{{Endoscopy Urologic procedures Endoscopy