This is a list of genes, proteins or receptors named A1 or Alpha-1 :
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Actin, alpha 1
Actin, alpha skeletal muscle is a protein that in humans is encoded by the ''ACTA1'' gene.
Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins ...
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Actinin, alpha 1
Alpha-actinin-1 is a protein that in humans is encoded by the ''ACTN1'' gene.
Function
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins an ...
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Adaptor-related protein complex 2, alpha 1
AP-2 complex subunit alpha-1 is a protein that in humans is encoded by the ''AP2A1'' gene.
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP2 adaptors) complex found in clathrin coated vesicles. The AP-2 complex is a hete ...
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Aldehyde dehydrogenase 3 family, member A1
Aldehyde dehydrogenase, dimeric NADP-preferring is an enzyme that in humans is encoded by the ''ALDH3A1'' gene.
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-deriv ...
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Aldehyde dehydrogenase 4 family, member A1
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Aldehyde dehydrogenase 5 family, member A1
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Aldehyde dehydrogenase 6 family, member A1
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Aldehyde dehydrogenase 9 family, member A1
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Aldehyde dehydrogenase 18 family, member A1
Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ''ALDH18A1'' gene.
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enz ...
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Aldo-keto reductase family 1, member A1
Alcohol dehydrogenase ADP+'' also known as aldehyde reductase or aldo-keto reductase family 1 member A1 is an enzyme that in humans is encoded by the ''AKR1A1'' gene. AKR1A1 belongs to the aldo-keto reductase (AKR) superfamily. It catalyzes the ...
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Alpha-1-microglobulin/bikunin precursor
Protein AMBP is a protein that in humans is encoded by the ''AMBP'' gene.
Interactions
Alpha-1-microglobulin/bikunin precursor has been shown to interact with CD79A.
See also
* Inter-alpha-trypsin inhibitor
* Alpha-1-microglobulin
Referen ...
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Apolipoprotein A1
Apolipoprotein AI (ApoA-I) is a protein that in humans is encoded by the ''APOA1'' gene. As the major component of HDL particles, it has a specific role in lipid metabolism.
Structure
''APOA1'' is located on chromosome 11, with its specific ...
and
ApoA-1 Milano
Apolipoprotein A-1 Milano (also ETC-216, now MDCO-216) is a naturally occurring mutated variant of the apolipoprotein A1 protein found in human HDL, the lipoprotein particle that carries cholesterol from tissues to the liver and is associated wi ...
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ATPase, H+ transporting, lysosomal V0 subunit a1
V-type proton ATPase 116 kDa subunit a isoform 1 is an enzyme that in humans is encoded by the ''ATP6V0A1'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity... ...
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ATPase, Na+/K+ transporting, alpha 1
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BCL2-related protein A1
Bcl-2-related protein A1 is a protein that in humans is encoded by the ''BCL2A1'' gene.
Function
This gene encodes a member of the bcl2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro- apoptotic r ...
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Butyrophilin, subfamily 1, member A1
Butyrophilin subfamily 1 member A1 is a protein that in humans is encoded by the ''BTN1A1'' gene.
Butyrophilin (BTN) is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a ce ...
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Butyrophilin, subfamily 3, member A1
Butyrophilin subfamily 3 member A1 is a protein that in humans is encoded by the ''BTN3A1'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''gene ...
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Capping protein (actin filament) muscle Z-line, alpha 1
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Carboxypeptidase A1
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Casein kinase 1, alpha 1
Casein kinase I isoform alpha is an enzyme that in humans is encoded by the ''CSNK1A1'' gene.
Interactions
Casein kinase 1, alpha 1 has been shown to Protein-protein interaction, interact with Centaurin, alpha 1 and AXIN1.
See also
* Casein ...
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Casein kinase 2, alpha 1
Casein kinase II subunit alpha is an enzyme that in humans is encoded by the ''CSNK2A1'' gene.
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is comp ...
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Catenin (cadherin-associated protein), alpha 1
αE-catenin, also known as Catenin alpha-1 is a protein that in humans is encoded by the ''CTNNA1'' gene. αE-catenin is highly expressed in cardiac muscle and localizes to adherens junctions at intercalated disc structures where it functions to ...
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Centaurin, alpha 1
Arf-GAP with dual PH domain-containing protein 1 is a protein that in humans is encoded by the ''ADAP1'' gene.
Interactions
Centaurin, alpha 1 has been shown to interact with:
* Casein kinase 1, alpha 1
* Nucleolin,
* P110α,
* PRKCI,
* ...
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Cholinergic receptor, nicotinic, alpha 1
Neuronal acetylcholine receptor subunit alpha-1, also known as nAChRα1, is a protein that in humans is encoded by the ''CHRNA1'' gene. The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR).
The musc ...
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Coagulation factor XIII, A1 polypeptide
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collagen, type I, alpha 1
Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is a protein that in humans is encoded by the gene. ''COL1A1'' encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including ...
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collagen, type II, alpha 1
Collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital), also known as COL2A1, is a human gene that provides instructions for the production of the pro-alpha1(II) chain of type II collagen.
Function
This ...
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Collagen, type III, alpha 1
Type III Collagen is a homotrimer, or a protein composed of three identical peptide chains (monomers), each called an alpha 1 chain of type III collagen. Formally, the monomers are called collagen type III, alpha-1 chain and in humans are encoded ...
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Collagen, type IV, alpha 1
Collagen alpha-1(IV) chain (COL4A1) is a protein that in humans is encoded by the ''COL4A1'' gene on chromosome 13. It is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of the type IV collagen and plays a role in angiog ...
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Collagen, type V, alpha 1
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Collagen, type VI, alpha 1
Collagen alpha-1(VI) chain is a protein that in humans is encoded by the ''COL6A1'' gene.
Function
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix ...
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Collagen, type VII, alpha 1
Collagen alpha-1(VII) chain is a protein that in humans is encoded by the ''COL7A1'' gene. It is composed of a triple helical, collagenous domain flanked by two non-collagenous domains, and functions as an anchoring fibril between the dermal-epide ...
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Collagen, type VIII, alpha 1
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Collagen, type IX, alpha 1
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Collagen, type X, alpha 1
Collagen alpha-1(X) chain is a protein that in humans is a member of the collagen family encoded by the ''COL10A1'' gene.
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during e ...
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Collagen, type XI, alpha 1
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Collagen, type XII, alpha 1
Collagen alpha-1(XII) chain is a protein that in humans is encoded by the ''COL12A1'' gene.
This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family ...
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Collagen, type XIII, alpha 1
Collagen alpha-1(XIII) chain is a protein that in humans is encoded by the ''COL13A1'' gene.
This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at ...
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Collagen, type XIV, alpha 1
Collagen alpha-1(XIV) chain is a protein that in humans is encoded by the ''COL14A1'' gene.
It likely plays a role in collagen binding and cell-cell adhesion.
References
Further reading
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Collagens
{ ...
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Collagen, type XV, alpha 1
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Collagen, type XVI, alpha 1
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Collagen, type XVII, alpha 1
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Collagen, type XVIII, alpha 1
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Collagen, type XIX, alpha 1
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Collagen, type XXV, alpha 1
Collagen alpha-1(XXV) chain is a protein that in humans is encoded by the ''COL25A1'' gene.
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen ...
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Collagen, type XXVII, alpha 1
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Crystallin, beta A1
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Cyclic nucleotide-gated channel alpha 1
Cyclic nucleotide-gated channel alpha 1, also known as CNGA1, is a human gene encoding an ion channel protein. Heterologously expressed CNGA1 can form a functional channel that is permeable to calcium. In rod photoreceptors, however, CNGA1 forms ...
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Cyclin A1
Cyclin-A1 is a protein that in humans is encoded by the ''CCNA1'' gene.
Function
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance thro ...
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Cytochrome P450, family 1, member A1
Cytochrome P450, family 1, subfamily A, polypeptide 1 is a protein
that in humans is encoded by the ''CYP1A1'' gene.
The protein is a member of the cytochrome P450 superfamily of enzymes.
Function
Metabolism of xenobiotics and drugs
CYP1A1 ...
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Defensin, alpha 1
Defensin, alpha 1 also known as human alpha defensin 1, human neutrophil peptide 1 (HNP-1) or neutrophil defensin 1 is a human protein that is encoded by the ''DEFA1'' gene. Human alpha defensin 1 belongs to the alpha defensin family of antimicr ...
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Dystrophin-associated protein A1
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Ephrin A1
Ephrin A1 is a protein that in humans is encoded by the ''EFNA1'' gene.
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been ...
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Eukaryotic translation elongation factor 1 alpha 1
Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes. In humans, it is encoded by the ''EEF1A1'' gene.
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which i ...
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Family with sequence similarity 13, member A1
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Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
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Gamma-aminobutyric acid (GABA) A receptor, alpha 1
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Gap junction protein, alpha 1
Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the ''GJA1'' gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular ...
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GDNF family receptor alpha 1
GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor, is a protein that in humans is encoded by the ''GFRA1'' gene.
Function
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, ...
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Glutathione S-transferase A1
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Glycine receptor, alpha 1
Glycine receptor subunit alpha-1 is a protein that in humans is encoded by the ''GLRA1'' gene.
Function
The inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a ...
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Heat shock protein 90kDa alpha (cytosolic), member A1
Heat shock protein HSP 90-alpha is a protein that in humans is encoded by the ''HSP90AA1'' gene.
Function
The gene, HSP90AA1, encodes the human stress-inducible 90-kDa heat shock protein alpha (Hsp90A). Complemented by the constitutively ex ...
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Hemoglobin, alpha 1
Hemoglobin subunit alpha, Hemoglobin, alpha 1, is a hemoglobin protein that in humans is encoded by the ''HBA1'' gene.
Gene
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseu ...
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Heterogeneous nuclear ribonucleoprotein A1
Heterogeneous nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the ''HNRNPA1'' gene. Mutations in hnRNP A1 are causative of amyotrophic lateral sclerosis and the syndrome multisystem proteinopathy.
Function
This ge ...
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Homeobox A1
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Immunoglobulin heavy constant alpha 1
Immunoglobulin heavy constant alpha 1 is a immunoglobulin gene with symbol ''IGHA1''. It encodes a constant (C) segment of Immunoglobulin A heavy chain. Immunoglobulin A is an antibody that plays a critical role in immune function in the mucous m ...
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Importin alpha 1
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Interferon, alpha 1
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Interleukin 13 receptor, alpha 1
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Karyopherin alpha 1
Importin subunit alpha-5 is a protein that in humans is encoded by the ''KPNA1'' gene.
Interactions
Importin subunit alpha-5 has been shown to interact with KPNB1 and UBR5
E3 ubiquitin-protein ligase UBR5 is an enzyme that in humans is encoded by ...
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Laminin, alpha 1
Laminin subunit alpha-1 is a protein that in humans is encoded by the ''LAMA1'' gene.
Interactions
Laminin, alpha 1 has been shown to interact with FBLN2
Fibulin-2 is a protein that in humans is encoded by the ''FBLN2'' gene.
This gene encodes a ...
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Major histocompatibility complex, class II, DP alpha 1
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Major histocompatibility complex, class II, DQ alpha 1
Major histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene present on short arm of chromosome 6 (6p21.3) and also denotes the genetic locus which contains this gene. The protein encoded by this gene is one of tw ...
* Myosin light chain A1, an
actin-binding protein Actin-binding proteins (also known as ABPs) are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both.
Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do t ...
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NADH dehydrogenase (ubiquinone), alpha 1
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Nucleolar protein, member A1
H/ACA ribonucleoprotein complex subunit 1 is a protein that in humans is encoded by the ''GAR1'' gene.
Function
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects ...
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PCDHA4
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Phospholipase A1
Phospholipase A1 (EC 3.1.1.32; systematic name: phosphatidylcholine 1-acylhydrolase) encoded by the PLA1A gene is a phospholipase enzyme which removes the 1-acyl group:
:phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate
It ...
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Phosphorylase kinase, alpha 1
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Plexin A1
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Polymerase (DNA directed), alpha 1
DNA polymerase alpha also known as ''Pol α'' is an enzyme complex found in eukaryotes that is involved in initiation of DNA replication. The DNA polymerase alpha complex consists of 4 subunits: POLA1, POLA2, PRIM1, and PRIM2.
Pol α has limite ...
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Proteasome (prosome, macropain) subunit, alpha 1
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Protein kinase, AMP-activated, alpha 1
5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the ''PRKAA1'' gene.
The protein encoded by this gene belongs to the serine/threonine protein kinase family. It is the catalytic subunit of the 5' ...
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Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
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Protocadherin alpha 1
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Pulmonary surfactant-associated protein A1
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Pyruvate dehydrogenase (lipoamide) alpha 1
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RNA binding motif protein, Y-linked, family 1, member A1
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Replication protein A1
Replication protein A 70 kDa DNA-binding subunit is a protein that in humans is encoded by the ''RPA1'' gene.
Interactions
Replication protein A1 has been shown to interact with:
* BRCA2,
* BLM,
* MCM2,
* MCM4,
* MCM6,
* MCM7,
* MU ...
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S100 calcium binding protein A1
Protein S100-A1, also known as S100 calcium-binding protein A1 is a protein which in humans is encoded by the ''S100A1'' gene. S100A1 is highly expressed in cardiac and skeletal muscle, and localizes to Z-discs and sarcoplasmic reticulum. S100A1 ...
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Sec61 alpha 1
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Serum amyloid A1
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Solute carrier family 35 (CMP-sialic acid transporter), member A1
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Spectrin, alpha 1
Spectrin alpha chain, erythrocyte is a protein that in humans is encoded by the ''SPTA1'' gene.
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the deter ...
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Sperm protein associated with the nucleus, X-linked, family member A1
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Syntrophin, alpha 1
Alpha-1-syntrophin is a protein that in humans is encoded by the ''SNTA1'' gene. Alpha-1 syntrophin is a signal transducing adaptor protein and serves as a scaffold for various signaling molecules. Alpha-1 syntrophin contains a PDZ domain, two Ple ...
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Transient receptor potential cation channel, member A1
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Wasabi Receptor, is a protein that in humans is encoded by the ''TRPA1'' (and in mice and rats by the ''Trpa1 ...
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UDP glucuronosyltransferase 1 family, polypeptide A1
UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the ''UGT1A1'' gene.
UGT-1A is a uridine diphosphate glucuronosyltransferase (UDP-glucuronosyltransferase, UDPGT), an enzyme of the glucuronidation pat ...
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Urea Transporter A1
* a gene found in the maize encoding for the dihydroflavonol 4-reductase (reducing dihydroflavonols into flavan-4-ols) in the
phlobaphene
Phlobaphenes (or phlobaphens, CAS No.:71663-19-9) are reddish, alcohol-soluble and water-insoluble phenolic substances. They can be extracted from plants, or be the result from treatment of tannin extracts with mineral acids (tanner's red). The nam ...
metabolic pathway
; proteins :
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α-1-antitrypsin, an acute-phase protein in the Alpha 1-antitrypsin deficiency, a genetic disorder
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Annexin A1
Annexin A1, also known as lipocortin I, is a protein that is encoded by the ''ANXA1'' gene in humans.
Function
Annexin A1 belongs to the annexin family of Ca2+-dependent phospholipid-binding proteins that have a molecular weight of approximat ...
, a human protein
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Outer membrane phospholipase A1
Outer membrane phospholipase A1 (OMPLA) is an acyl hydrolase with a broad substrate specificity (EC:3.1.1.32.) from the bacterial outer membrane. It has been proposed that Ser164 is the active site of the protein (UniProt )
This integral memb ...
, a bacterial protein
; receptors :
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α-1-Adrenoceptor, an adrenergic receptor with the primary effect of vasoconstriction
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Alpha-1 blocker
Alpha-1 blockers (also called alpha-adrenergic blocking agents or alpha-1 antagonists) constitute a variety of drugs that block the effect of catecholamines on alpha-1-adrenergic receptors. They are mainly used to treat benign prostatic hyperpla ...
, a variety of drugs which block α1-adrenergic receptors in arteries and smooth muscles
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Adenosine A1 receptor
The adenosine A1 receptor is one member of the adenosine receptor group of G protein-coupled receptors with adenosine as endogenous ligand.
Biochemistry
A1 receptors are implicated in sleep promotion by inhibiting wake-promoting cholinergic neu ...
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EPH receptor A1
EPH receptor A1 (ephrin type-A receptor 1) is a protein that in humans is encoded by the ''EPHA1'' gene.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated ...
* A1, a subfamily of
rhodopsin-like receptors
Rhodopsin-like receptors are a family of proteins that comprise the largest group of G protein-coupled receptors.
Scope
G-protein-coupled receptors, GPCRs, constitute a vast protein family that encompasses a wide range of functions (including ...
* SR-A1, a type of
scavenger receptors
; domains :
* CTA1, a portion of the
cholera toxin
Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is AB5 multimeric protein complex secreted by the bacterium '' Vibrio cholerae''. CTX is responsible for the massive, watery diarrhea characteristic of choler ...
chain
; alleles :
* A1, an allele in the DRD2 TaqI polymorphism that could be involved in
alcoholism
Alcoholism is, broadly, any drinking of alcohol that results in significant mental or physical health problems. Because there is disagreement on the definition of the word ''alcoholism'', it is not a recognized diagnostic entity. Predomina ...
{{DEFAULTSORT:A1 genes, proteins or receptors
Receptor
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