Montreal Experiments
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The Montreal experiments were a series of experiments, initially aimed to treat
schizophrenia Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, f ...
by changing memories and erasing the patients' thoughts using the Scottish psychiatrist
Donald Ewen Cameron Donald Ewen Cameron ( – ) was a Scottish-born psychiatrist. He is largely known today for his central role in unethical medical experiments, and development of psychological and medical torture techniques for the Central Intelligence Agency. ...
's method of "
psychic driving Psychic driving was a psychiatric procedure of the 1950s and 1960s in which patients were subjected to a continuously repeated audio message on a looped tape to alter their behaviour. In psychic driving, patients were often exposed to hundreds of t ...
", as well as drug-induced sleep, intensive
electroconvulsive therapy Electroconvulsive therapy (ECT) is a psychiatry, psychiatric treatment that causes a generalized seizure by passing electrical current through the brain. ECT is often used as an intervention for mental disorders when other treatments are inadequ ...
,
sensory deprivation Sensory deprivation or perceptual isolation is the deliberate reduction or removal of stimuli from one or more of the senses. Simple devices such as blindfolds or hoods and earmuffs can cut off sight and hearing, while more complex devices can ...
and
Thorazine Chlorpromazine (CPZ), marketed under the brand names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar dis ...
. The experiments were conducted at the
Allan Memorial Institute The Allan Memorial Institute (AMI; ), also known colloquially as "the Allan", is a former psychiatric hospital and research institute located at 1025 Pine Avenue West in Montreal, Canada. It is situated on the slope of Mount Royal on the McGil ...
of
McGill University McGill University (French: Université McGill) is an English-language public research university in Montreal, Quebec, Canada. Founded in 1821 by royal charter,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, ...
in Montreal between 1957 and 1964 by Cameron and funded by the
CIA The Central Intelligence Agency (CIA; ) is a civilian foreign intelligence service of the federal government of the United States tasked with advancing national security through collecting and analyzing intelligence from around the world and ...
as part of
Project MKUltra MKUltra was an illegal human experimentation program designed and undertaken by the U.S. Central Intelligence Agency (CIA) to develop procedures and identify drugs that could be used during interrogations to weaken individuals and force confes ...
, which lasted until 1973 and was only revealed to the public in 1975. The patients of this experiment expected positive changes from Cameron's treatment. However, these patients suffered severely under conditions that were not in accordance with
human rights Human rights are universally recognized Morality, moral principles or Social norm, norms that establish standards of human behavior and are often protected by both Municipal law, national and international laws. These rights are considered ...
. Not only the patients but also their families show long lasting effects on their mental health. Some of these symptoms include
retrograde amnesia In neurology, retrograde amnesia (RA) is the inability to access memories or information from before an injury or disease occurred. RA differs from a similar condition called anterograde amnesia (AA), which is the inability to form new memories f ...
as well as impairments in everyday life abilities such as self-care. Details of the experiments has been kept out of the public domain the CIA, by the destruction of files or by the use of
non-disclosure agreement A non-disclosure agreement (NDA), also known as a confidentiality agreement (CA), confidential disclosure agreement (CDA), proprietary information agreement (PIA), or secrecy agreement (SA), is a legal contract or part of a contract between at le ...
s. Whether or not Cameron was aware that funding for his experiments was coming from the CIA is unclear; it has been argued that he would have carried out the exact same experiments if funding had come from a source without ulterior motives.


Donald Ewen Cameron

Donald Ewen Cameron was the key figure in the Montreal experiments. Cameron was born on December 24, 1901, in Scotland and graduated from the
University of Glasgow The University of Glasgow (abbreviated as ''Glas.'' in Post-nominal letters, post-nominals; ) is a Public university, public research university in Glasgow, Scotland. Founded by papal bull in , it is the List of oldest universities in continuous ...
in 1924. In 1929 he moved to Canada where he worked in the Brandon Mental Hospital in
Manitoba Manitoba is a Provinces and territories of Canada, province of Canada at the Centre of Canada, longitudinal centre of the country. It is Canada's Population of Canada by province and territory, fifth-most populous province, with a population ...
as the physician in charge. In 1938 he received his diploma in psychiatry and became professor of neurology, psychiatry at
University at Albany The State University of New York at Albany (University at Albany, UAlbany, or SUNY Albany) is a Public university, public research university in Albany, New York, United States. Founded in 1844, it is one of four "university centers" of the St ...
and began his research on
sensory deprivation Sensory deprivation or perceptual isolation is the deliberate reduction or removal of stimuli from one or more of the senses. Simple devices such as blindfolds or hoods and earmuffs can cut off sight and hearing, while more complex devices can ...
and memory. In 1953 he developed his theory of "
psychic driving Psychic driving was a psychiatric procedure of the 1950s and 1960s in which patients were subjected to a continuously repeated audio message on a looped tape to alter their behaviour. In psychic driving, patients were often exposed to hundreds of t ...
" to cure schizophrenia which he later used on his patients under the Project MKUltra, with the codename "Subproject 68" for which he was recruited by the
CIA The Central Intelligence Agency (CIA; ) is a civilian foreign intelligence service of the federal government of the United States tasked with advancing national security through collecting and analyzing intelligence from around the world and ...
in 1957. He was paid $69,000 through the front company "Society for the Investigation of Human Ecology" from 1957 to 1964 to carry out these experiments, as well as receiving "more than $500,000 between 1950 and 1965" from the federal government. He suddenly left the project four years before the end of his contract. In 1961 he became president of the
World Psychiatric Association The World Psychiatric Association (WPA) is an international Umbrella organization, umbrella organisation of psychiatric societies. Objectives and goals Originally created to produce world psychiatric congresses, it has evolved to hold regional ...
after he had already been the president of both the
American Psychiatric Association The American Psychiatric Association (APA) is the main professional organization of psychiatrists and trainee psychiatrists in the United States, and the largest psychiatric organization in the world. It has more than 39,200 members who are in ...
as well as the Canadian Psychiatric Association. In 1967 he died of a heart attack.


Treatment

With the goal of inducing lifelong changes in humans, Cameron used different methods of depatterning and repatterning the brain. The procedures included
psychic driving Psychic driving was a psychiatric procedure of the 1950s and 1960s in which patients were subjected to a continuously repeated audio message on a looped tape to alter their behaviour. In psychic driving, patients were often exposed to hundreds of t ...
, drug-induced sleep, intensive
electroconvulsive therapy Electroconvulsive therapy (ECT) is a psychiatry, psychiatric treatment that causes a generalized seizure by passing electrical current through the brain. ECT is often used as an intervention for mental disorders when other treatments are inadequ ...
,
sensory deprivation Sensory deprivation or perceptual isolation is the deliberate reduction or removal of stimuli from one or more of the senses. Simple devices such as blindfolds or hoods and earmuffs can cut off sight and hearing, while more complex devices can ...
and the administration of neuroleptic
Thorazine Chlorpromazine (CPZ), marketed under the brand names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar dis ...
.


Drug-induced sleep

Cameron used doses of
thorazine Chlorpromazine (CPZ), marketed under the brand names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar dis ...
to put patients into an artificial coma. The drug-induced sleep, which took place in the "sleep room", usually lasted from a few days up to 86 days; longer than expected by the patients. Cameron often combined the sleep periods with injections of
hallucinogenic drugs Hallucinogens, also known as psychedelics, entheogens, or historically as psychotomimetics, are a large and diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, moo ...
(e.g.
LSD Lysergic acid diethylamide, commonly known as LSD (from German ; often referred to as acid or lucy), is a semisynthetic, hallucinogenic compound derived from ergot, known for its powerful psychological effects and serotonergic activity. I ...
), as well as administration of electroshocks and the playing of pre-recorded messages into patients' ears.


Electroconvulsive therapy (ECT)

Electroconvulsive therapy (also called electroshock therapy) is a procedure used to treat psychological disorders like
treatment-resistant depression Treatment-resistant depression (TRD) is often defined as major depressive disorder in which an affected person does not respond adequately to at least two different antidepressant medications at an adequate dose and for an adequate duration. Inad ...
. Another way of depatterning the brain was intensive
electroconvulsive therapy Electroconvulsive therapy (ECT) is a psychiatry, psychiatric treatment that causes a generalized seizure by passing electrical current through the brain. ECT is often used as an intervention for mental disorders when other treatments are inadequ ...
(electroshock therapy). Usually, 2 to 3 daily sessions were ordered, consisting of six 150-Volt shocks that lasted one second. After 30-40 daily sessions, Cameron progressively reduced the sessions and finished the treatment after a two-year follow up program with one session per month.


Sensory deprivation

Inspired by Donald Hebb's experiment on
sensory deprivation Sensory deprivation or perceptual isolation is the deliberate reduction or removal of stimuli from one or more of the senses. Simple devices such as blindfolds or hoods and earmuffs can cut off sight and hearing, while more complex devices can ...
and human cognition, Cameron included these techniques in his treatment program. Patients were deprived of their senses by covering ears, eyes and/or skin. Furthermore, patients were given little food, water and oxygen, and instead injected with drugs (
LSD Lysergic acid diethylamide, commonly known as LSD (from German ; often referred to as acid or lucy), is a semisynthetic, hallucinogenic compound derived from ergot, known for its powerful psychological effects and serotonergic activity. I ...
,
curare Curare ( or ; or ) is a common name for various alkaloid arrow poisons originating from plant extracts. Used as a paralyzing agent by indigenous peoples in Central and South America for hunting and for therapeutic purposes, curare only ...
) to keep them in a paralyzed state.


Psychic driving

In order to repattern the brain, patients had to listen to specific recordings of Cameron repeatedly. This process took place for up to 16 hours a day, and over the whole period messages could be repeated up to half a million times altogether. For the first ten days, recordings contained personal, negative messages, which were followed by ten days of positive messages. Anxiety that would emerge in patients was countered with heavy doses of sedating drugs such as Sodium Amytal and
Largactil Chlorpromazine (CPZ), marketed under the brand names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar dis ...
.


Subjects

It is unknown how many people were subjected to the Montreal Experiments exactly, but over 300 people applied for compensation in 1992 with the Canadian Government. The subjects of the experiment mainly had mental health issues like depression and
schizophrenia Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, f ...
, and were hoping to get treated for these illnesses by Cameron. None of them had given
informed consent Informed consent is an applied ethics principle that a person must have sufficient information and understanding before making decisions about accepting risk. Pertinent information may include risks and benefits of treatments, alternative treatme ...
to the procedures, or were aware of the experiments being conducted. This was a gross violation of the
Nuremberg Code The Nuremberg Code () is a set of research ethics, ethical research principles for human experimentation created by the court in ''Doctors' trial, U.S. v Brandt'', one of the Subsequent Nuremberg trials that were held after the World War II, Seco ...
, a code of ethics set up after
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
. Children and adults from many social backgrounds were experimented on, most of them for up to three years. Victims often suffered from
retrograde amnesia In neurology, retrograde amnesia (RA) is the inability to access memories or information from before an injury or disease occurred. RA differs from a similar condition called anterograde amnesia (AA), which is the inability to form new memories f ...
for the rest of their lives and had to relearn most skills they had. Many were in a childlike state and even had to be toilet-trained. Family described them as even more emotionally unstable as before and some of them were unable to live a normal life afterwards. One such victim was Jean Steel, whose daughter said that she never returned to be the same woman ever again. Jean would sit alone in the dark, write codes on the walls, and according to her daughter, "her emotions were stripped. It took away her soul."


Aftermath

Project MKUltra MKUltra was an illegal human experimentation program designed and undertaken by the U.S. Central Intelligence Agency (CIA) to develop procedures and identify drugs that could be used during interrogations to weaken individuals and force confes ...
officially ended in 1973, around the time that the
Watergate scandal The Watergate scandal was a major political scandal in the United States involving the Presidency of Richard Nixon, administration of President Richard Nixon. The scandal began in 1972 and ultimately led to Resignation of Richard Nixon, Nix ...
broke. It was not until 1975 that the general public was informed about the extent of CIA meddling, largely due to the involvement of the
Church Committee The Church Committee (formally the United States Senate Select Committee to Study Governmental Operations with Respect to Intelligence Activities) was a US Senate select committee in 1975 that investigated abuses by the Central Intelligence ...
, which was tasked with the investigation of "the extent, if any, to which illegal, improper, or unethical activities were engaged in by any agency of the Federal Government," During the 1977 Senate Hearing on MKUltra, Senator Edward "Ted" Kennedy called for the release of all documents pertaining to MKUltra, saying "the best way to put this period behind us, obviously, is to have the full information…" The Senate Hearing also allowed the CIA Director of the time,
Stansfield Turner Stansfield Turner (December 1, 1923 January 18, 2018) was an admiral in the United States Navy who served as President of the Naval War College (1972–1974), commander of the United States Second Fleet (1974–1975), and Supreme Allied Command ...
, to give his prepared statement and to elaborate on the discovery of seven boxes of information related to Project MKUltra, most of which turned out to consist of "approvals for advance of funds, vouchers, accountings, and the like - most of which are not very informative as to the nature of the activities that were undertaken." This made it very difficult to judge the extent of CIA involvement with the Montreal Experiments. More information was revealed in the Canadian CBC documentary series " The Fifth Estate". In March 1980, they released a first episode about Project MKUltra, which not only held the testimony of two Canadian patients who'd undergone the treatment speaking out for the first time, but also the revelation that Ottawa had aided to suppress information that CIA officials had apologised to the Canadian government following the initial revelation of the experimentation. The second episode, released in 2017, focuses on the present-day struggle of the victims to receive compensation, the hindrances made to prevent them from speaking out about their experiences, and the efforts of the CIA and Canadian government to keep their involvement hidden. Mentioned in particular are a 1988 class action settlement made by the victims against the CIA, which they won, receiving 67,000 US dollars each, and a 1992 compensation from the Canadian government, in which 77 individuals received 100,000 US dollars each, but signed away their right to sue the government or the hospital. This compensation did not extend to 250 other victims, denied for not being "
torture Torture is the deliberate infliction of severe pain or suffering on a person for reasons including corporal punishment, punishment, forced confession, extracting a confession, interrogational torture, interrogation for information, or intimid ...
d enough, applied too late or because they couldn't produce medical records." Neither the Canadian government nor the CIA have issued formal apologies for their involvement and funding of Project MKUltra or the Montreal experiments. A 1986 report found that government officials were not fully aware of Cameron's experiments. In 2017, the Canadian government reached an out-of-court settlement with the daughter of one of the patients, paying 100,000 US dollars in exchange for dropping the legal case, and signing a non-disclosure agreement which would prevent her from talking about the settlement.


Criticism

There is no clear evidence of what really happened in the Montreal Experiments. None of Cameron's personal files concerning his experiments survived. Other documents which would verify the Montreal Experiments either no longer exist or are still classified. Most of the information on the experiments is rooted in reports of victims, especially their journals or court reports.


References

{{Reflist Clinical research ethics Experimental psychology Human rights abuses in Canada Human rights abuses in the United States Human subject research in psychiatry Human subject research in Canada Human subject research in the United States Psychiatric assessment Schizophrenia research