Momordenol (3β-hydroxy-stigmasta-5,14-dien-16-one) is a natural
chemical compound
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element ...
, a
sterol
A sterol is any organic compound with a Skeletal formula, skeleton closely related to Cholestanol, cholestan-3-ol. The simplest sterol is gonan-3-ol, which has a formula of , and is derived from that of gonane by replacement of a hydrogen atom on ...
found in the fresh fruit of the
bitter melon
''Momordica charantia'' (commonly called bitter melon, cerassee, goya, bitter apple, bitter gourd, bitter squash, balsam-pear, karela, karavila and many more #Uses, names listed below) is a tropical and subtropical vine of the family Cucurbitac ...
(''Momordica charantia'').
The compound is soluble in
ethyl acetate
Ethyl acetate commonly abbreviated EtOAc, ETAC or EA) is the organic compound with the formula , simplified to . This flammable, colorless liquid has a characteristic sweet smell (similar to pear drops) and is used in glues, nail polish removers, ...
and
methanol
Methanol (also called methyl alcohol and wood spirit, amongst other names) is an organic chemical compound and the simplest aliphatic Alcohol (chemistry), alcohol, with the chemical formula (a methyl group linked to a hydroxyl group, often ab ...
but not in pure
chloroform
Chloroform, or trichloromethane (often abbreviated as TCM), is an organochloride with the formula and a common solvent. It is a volatile, colorless, sweet-smelling, dense liquid produced on a large scale as a precursor to refrigerants and po ...
or
petrol
Gasoline (North American English) or petrol ( Commonwealth English) is a petrochemical product characterized as a transparent, yellowish, and flammable liquid normally used as a fuel for spark-ignited internal combustion engines. When formul ...
. It crystallizes as fine needles that melt at 160–161 °C. It was isolated in 1997 by S. Begum and others.
[
]
See also
* Momordicilin
Momordicilin or 24- ′-hydroxy,1′-methyl-2′-pentenyloxylursan-3-one is a chemical compound, a triterpenoid with formula , found in the fresh fruit of the bitter melon (''Momordica charantia'').Sabira Begum, Mansour Ahmed, Bina S. Siddiqui, Ab ...
* Momordicin I
Momordicin I, or 3,7,23-trihydroxycucurbitan-5,24-dien-19-al, is a chemical compound found in the leaves of the bitter melon vine (''Momordica charantia''), possibly responsible for its reputed medicinal properties.
The compound was isolated and ...
* Momordicin-28
Momordicin-28 or 13-hydroxy-28-methoxy-urs-11-en-3-one is a triterpene compound with formula found in the fresh fruit of the bitter melon (''Momordica charantia'').Sabira Begum, Mansour Ahmed, Bina S. Siddiqui, Abdullah Khan, Zafar S. Saify, and ...
* Momordicinin
Momordicinin (13β,28-epoxy-urs-11-en-3-one) is chemical compound, a triterpene with formula , found in the fresh fruit of the bitter melon (''Momordica charantia'').
The compound is soluble in ethyl acetate and chloroform but not in petrol. It ...
* Momordol
* Stigmasterol
Stigmasterol – a plant sterol (''phytosterol'') – is among the most abundant of plant sterols, having a major function to maintain the structure and physiology of cell membranes. In the European Union, it is a food additive listed with E nu ...
References
{{Phytosterols
Phytosterols
Ketones
Sterols