Metanx is a prescription

medical food Medical food is food that is specially formulated and intended for the dietary management of a disease that has distinctive nutritional needs that cannot be met by normal diet alone. In the United States, it was defined in the Food and Drug Admin ...

made by Alfasigma that contains L-methylfolate (as Metafolin, a calcium salt of vitamin B₉),

methylcobalamin Methylcobalamin (mecobalamin, MeCbl, or MeB) is a cobalamin, a form of vitamin B12, vitamin B. It differs from cyanocobalamin in that the cyanide, cyano group at the cobalt is replaced with a methyl group. Methylcobalamin features an octahedral ...

(vitamin B₁₂) and pyridoxal 5'-phosphate (vitamin B₆). It is a vitamin B supplement. Metanx is indicated for the dietary management of peripheral neuropathy (i.e. DPN).

Ingredients

Metanx contains the following active ingredients (per capsule): *

Folate Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as a dietary supplement and in food fortification as it is more stable during processing and ...

* L-methylfolate (Metafolin): 3 mg * Pyridoxal 5'-phosphate: 35 mg * Methylcobalamin: 2 mg (Google Books)

Indication and usage

Metanx is used for treating: * Painful

diabetic neuropathy Diabetic neuropathy includes various types of nerve damage associated with diabetes mellitus. The most common form, diabetic peripheral neuropathy, affects 30% of all diabetic patients. Studies suggests that cutaneous nerve branches, such as the s ...

, (Google Books) * Diabetic foot ulcers, *

Endothelial dysfunction In blood vessel diseases, endothelial dysfunction is an unhealthy state of the the cells that line the blood vessels (endothelium). The main cause of endothelial dysfunction is impaired bioavailability of nitric oxide. In addition to acting a ...

associated with diabetic

peripheral neuropathy Peripheral neuropathy, often shortened to neuropathy, refers to damage or disease affecting the nerves. Damage to nerves may impair sensation, movement, gland function, and/or organ function depending on which nerve fibers are affected. Neuropa ...

, *

Hyperhomocysteinemia Hyperhomocysteinemia is a medical condition characterized by an abnormally high level of total homocysteine (that is, including homocystine and homocysteine-cysteine disulfide) in the blood, conventionally described as above 15 μmol/L. As ...

References

B vitamins Medical food {{gastrointestinal-drug-stub