Mauna Kea Technologies
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Mauna Kea Technologies is a global
medical device A medical device is any device intended to be used for medical purposes. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assura ...
company focused on
endomicroscopy Endomicroscopy is a technique for obtaining histology-like images from inside the human body in real-time,Jabbour, J.M., et al., Confocal Endomicroscopy: Instrumentation and Medical Applications. Annals of biomedical engineering, 2011. a process kn ...
, the field of microscopic imaging during endoscopy procedures. The company researches, develops and markets tools to visualize, detect, and rule out abnormalities including malignant and pre-malignant tumors or lesions in the gastrointestinal and pulmonary tracts. The company makes Cellvizio, a probe-based Confocal Laser
Endomicroscopy Endomicroscopy is a technique for obtaining histology-like images from inside the human body in real-time,Jabbour, J.M., et al., Confocal Endomicroscopy: Instrumentation and Medical Applications. Annals of biomedical engineering, 2011. a process kn ...
(pCLE) system, which provides physicians and researchers with real-time access to histological information during standard endoscopy procedures through high-resolution cellular imaging of internal tissues. Cellvizio is used in medical applications such as gastrointestinal endoscopy, pulmonology and urology to help physicians diagnose lesions and make accurate treatment decisions in real-time. Cellvizio went public in July 2011 and trades on the
Euronext Paris Euronext Paris, formerly known as the Paris Bourse (), is a regulated securities trading venue in France. It is Europe's second largest stock exchange by market capitalization, behind the London Stock Exchange, as of December 2023. As of 2022, th ...
exchange.


Cellvizio Technology

Cellvizio technology generates cellular images using a small, flexible microscope, providing clinicians with microscopic images of tissue in a minimally-invasive manner. A real-time image processing software combined with a high-speed Laser Scanning Unit (LSU) allows Cellvizio to produce images at 12 frames per second. Confocal Imaging Cellvizio belongs to a specific category of microscopes, called confocal laser microscopes.


Timeline


Recent discoveries

Cellvizio probe-based confocal laser endomicroscopy technology or pCLE was instrumental in discovering the interstitium, a contiguous fluid-filled space existing between a structural barrier, such as a cell wall or the skin, and internal structures, such as organs, including muscles and the circulatory system. It is located in the submucosa that drains fluid into lymph nodes and is supported by collagen bundles. Researchers believe that this organ could be important in a number of pathological conditions including cancer metastasis, tissue edema and fibrosis, and has the potential of being the largest "organ" in the human body. Findings from the study co-led by an NYU Langone Health and Mount Sinai Beth were published in the March 27, 2018 issue of the peer-reviewed journal Scientific ReportsScientific American: Meet Your Interstitium, a Newfound "Organ"
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References

{{Authority control Medical technology companies of France Companies based in Paris Companies listed on Euronext Paris French companies established in 2000