Cellvizio
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Cellvizio
Mauna Kea Technologies is a global medical device company focused on endomicroscopy, the field of microscopic imaging during endoscopy procedures. The company researches, develops and markets tools to visualize, detect, and rule out abnormalities including malignant and pre-malignant tumors or lesions in the gastrointestinal and pulmonary tracts. The company makes Cellvizio, a probe-based Confocal Laser Endomicroscopy (pCLE) system, which provides physicians and researchers with real-time access to histological information during standard endoscopy procedures through high-resolution cellular imaging of internal tissues. Cellvizio is used in medical applications such as gastrointestinal endoscopy, pulmonology and urology to help physicians diagnose lesions and make accurate treatment decisions in real-time. Cellvizio went public in July 2011 and trades on the Euronext Paris exchange. Cellvizio Technology Cellvizio technology generates cellular images using a small, flexible micro ...
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Endomicroscopy
Endomicroscopy is a technique for obtaining histology-like images from inside the human body in real-time,Jabbour, J.M., et al., Confocal Endomicroscopy: Instrumentation and Medical Applications. Annals of biomedical engineering, 2011. a process known as ‘optical biopsy’.Sonn, G.a., et al., Optical biopsy of human bladder neoplasia with in vivo confocal laser endomicroscopy. The Journal of urology, 2009. 182: p. 1299-305. It generally refers to fluorescence confocal microscopy, although multi-photon microscopy and optical coherence tomography have also been adapted for endoscopic use.Jung, J.C., et al., In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy. Journal of neurophysiology, 2004. 92: p. 3121-33.Myaing, M.T., et al., Fiber-optic scanning two-photon fluorescence endoscope. Optics Letters, 2006. 31: p. 1076-78. Commercially available clinical and pre-clinical endomicroscopes can achieve a resolution on the order of a micrometre, have a fie ...
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Public Company
A public company is a company whose ownership is organized via shares of share capital, stock which are intended to be freely traded on a stock exchange or in over-the-counter (finance), over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listing (finance), listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states and so have associations and formal designations, which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation, though a corporation need not be a public company. In the United Kin ...
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Société Anonyme
The abbreviation S.A. or SA designates a type of limited company in certain countries, most of which have a Romance languages, Romance language as their official language and operate a derivative of the 1804, Napoleonic, civil law (legal system), civil law. Originally, shareholders could be anonymous and collect dividends by surrendering coupon (finance), coupons attached to their stock certificate, share certificates. Dividends were paid to whomever held the certificate. Since share certificates could be transferred privately, corporate management would not necessarily know who owned its shares – nor did anyone but the holders. As with bearer bonds, anonymous unregistered share ownership and dividend collection enabled money laundering, tax evasion, and concealed business transactions in general, so governments passed laws to audit the practice. Nowadays, shareholders of S.A.s are not anonymous, though shares can still be held by a holding company to obscure the benefici ...
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Euronext Growth
Euronext Growth is a multilateral trading facility (MTF) operated by Euronext. This stock exchange, equity trading market that was opened May 17, 2005 to address an opportunity posed by small to medium-sized business organizations, firms that were anticipated to desire easier access to an Stock market, equity market. The approach was to provide streamlined listing requirements and simplified trading rules to present a lesser load on small and mid-cap firms. The goal was to do this in a manner that also preserved good governance and transparency for investors. Euronext bills the Euronext Growth market as a unique option in the investing world. It aims to become the reference market for small and mid-sized companies throughout the Eurozone. Overview Euronext Growth serves as an alternative to the Euronext's regulated main market, focused on SMEs that may not yet meet the listing requirements for the main market or that prefer a more flexible framework. Euronext Growth is also Mul ...
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Paris
Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of cities in the European Union by population within city limits, fourth-most populous city in the European Union and the List of cities proper by population density, 30th most densely populated city in the world in 2022. Since the 17th century, Paris has been one of the world's major centres of finance, diplomacy, commerce, culture, Fashion capital, fashion, and gastronomy. Because of its leading role in the French art, arts and Science and technology in France, sciences and its early adoption of extensive street lighting, Paris became known as the City of Light in the 19th century. The City of Paris is the centre of the Île-de-France region, or Paris Region, with an official estimated population of 12,271,794 inhabitants in January 2023, or ...
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France
France, officially the French Republic, is a country located primarily in Western Europe. Overseas France, Its overseas regions and territories include French Guiana in South America, Saint Pierre and Miquelon in the Atlantic Ocean#North Atlantic, North Atlantic, the French West Indies, and List of islands of France, many islands in Oceania and the Indian Ocean, giving it Exclusive economic zone of France, one of the largest discontiguous exclusive economic zones in the world. Metropolitan France shares borders with Belgium and Luxembourg to the north; Germany to the northeast; Switzerland to the east; Italy and Monaco to the southeast; Andorra and Spain to the south; and a maritime border with the United Kingdom to the northwest. Its metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea. Its Regions of France, eighteen integral regions—five of which are overseas—span a combined area of and hav ...
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Medical Technology
Health technology is defined by the World Health Organization as the "application of organized knowledge and skills in the form of devices, medicines, vaccines, procedures, and systems developed to solve a health problem and improve quality of lives". This includes pharmaceuticals, devices, procedures, and organizational systems used in the healthcare industry, as well as computer-supported information systems. In the United States, these technologies involve standardized physical objects, as well as traditional and designed social means and methods to treat or care for patients. Development Pre-digital era During the pre-digital era, patients suffered from inefficient and faulty clinical systems, processes, and conditions. Many medical errors happened in the past due to undeveloped health technologies. Some examples of these medical errors included adverse drug events and alarm fatigue. When many alarms are repeatedly triggered or activated, especially for unimportant events ...
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Medical Device
A medical device is any device intended to be used for medical purposes. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assurance before regulating governments allow marketing of the device in their country. As a general rule, as the associated risk of the device increases the amount of testing required to establish safety and efficacy also increases. Further, as associated risk increases the potential benefit to the patient must also increase. Discovery of what would be considered a medical device by modern standards dates as far back as in Baluchistan where Neolithic dentists used flint-tipped drills and bowstrings. Study of Archaeology, archeology and Roman medical literature also indicate that many types of medical devices were in widespread use during the time of ancient Rome. In the United States it was not until the Federal Food, Drug, and Cosmetic Act ( ...
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Euronext Paris
Euronext Paris, formerly known as the Paris Bourse (), is a regulated securities trading venue in France. It is Europe's second largest stock exchange by market capitalization, behind the London Stock Exchange, as of December 2023. As of 2022, the 795 companies listed had a combined market capitalization of over US$4.58 trillion. Since September 2000, the Paris Bourse has been part of Euronext, of which it was a co-founder together with the Amsterdam Stock Exchange and Brussels Stock Exchange. It was subsequently rebranded Euronext Paris. History The Paris stock market started taking shape in the early 18th century, and first acquired prominence with trading of John Law's Company from 1717 to 1721. In 1724, a government decree gave it its first permanent regulation and is occasionally though dubiously taken as the market's starting point. From the second half of the 19th century, official stock markets in Paris were operated by the ''Compagnie des agents de change'', ...
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Interstitium
In anatomy, the interstitium is a contiguous fluid-filled space existing between a structural barrier, such as a cell membrane or the skin, and internal structures, such as organs, including muscles and the circulatory system. The fluid in this space is called interstitial fluid, comprises water and solutes which drains into the lymph system. The interstitial compartment is composed of connective and supporting tissues within the body called the ( extracellular matrix) that are situated outside the blood and lymphatic vessels and the parenchyma of organs. The role of the interstitium in solute concentration, protein transport and hydrostatic pressure impacts human pathology and physiological responses such as edema, inflammation and shock. Structure The non-fluid parts of the interstitium are predominantly collagen types I, III, and V; elastin; and glycosaminoglycans, such as hyaluronan and proteoglycans, that are cross-linked to form a honeycomb-like reticulum. Collagen bundles ...
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