Masoprocol is an
antineoplastic drug used to treat skin growths caused by sun exposure. It is the
meso form of
nordihydroguaiaretic acid that is taken by mouth. The substance is being studied in the treatment of prostate cancer.
Masoprocol is also called NDGA, and Actinex.
Mechanism
Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.
It is a
lipoxygenase inhibitor
Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase (5-lipoxygenase or 5-LOX) enzyme, which is responsible for the production of inflammatory leukotrienes. The overproduction of leuko ...
.
References
External links
MedlinePlus Drug InformationActinexentry in the public domain NCI Cancer Dictionary
Antineoplastic drugs
Catechols
Tetrols
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