Sir Martin Jonathan Landray (born ) is a British

physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...

epidemiologist Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population, and application of this knowledge to prevent diseases. It is a cornerstone ...

and

data scientist Data science is an interdisciplinary academic field that uses statistics, scientific computing, scientific methods, processing, scientific visualization, algorithms and systems to extract or extrapolate knowledge from potentially noisy, struct ...

who serves as a ''Professor of Medicine & Epidemiology'' at the

University of Oxford The University of Oxford is a collegiate university, collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the List of oldest un ...

. Landray designs, conducts and analyses large-scale

randomised control trial A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical t ...

s; including practice-changing international trials that have recruited over 100,000 individuals. Landray previously led the health informatics team that enabled the collection and management of data for the

UK Biobank UK Biobank is a long-term prospective biobank study in the United Kingdom (UK) that houses the de-identified biological samples and health-related data of half a million people. The volunteer participants aged 40-69 were recruited between 2006 ...

on over half a million people.

Early life and education

Landray was born the son of a general practitioner, Bob Landray and an anaesthetist, Margaret Bray. He was educated at

Abingdon School Abingdon School is an independent day and boarding school in Abingdon-on-Thames, Oxfordshire, England. It is the List of the oldest schools in the United Kingdom, twentieth oldest Independent School (UK), independent British school. In May 202 ...

Abingdon-on-Thames Abingdon-on-Thames ( ), commonly known as Abingdon, is a historic market town and civil parish on the River Thames in the Vale of the White Horse district of Oxfordshire, England. The Historic counties of England, historic county town of Berksh ...

, Oxfordshire, from 1982 until 1987. He was a prefect and played rugby and cricket. After Abingdon he went on to study medicine at the

University of Birmingham The University of Birmingham (informally Birmingham University) is a Public university, public research university in Birmingham, England. It received its royal charter in 1900 as a successor to Queen's College, Birmingham (founded in 1825 as ...

, returning later for specialist training in Clinical Pharmacology & Therapeutics, and General Internal Medicine.

Career

Landray serves as co-chief investigator of the

RECOVERY Trial The Randomised Evaluation of COVID-19 Therapy (RECOVERY Trial) is a large-enrollment clinical trial of possible treatments for people in the United Kingdom admitted to hospital with severe COVID-19 infection. The trial was later expanded to ...

into treatment drugs for

COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever ...

(the largest such clinical trial in the world) alongside Peter Horby. In June 2020, the trial discovered the first known life-saving COVID-19 drug,

Dexamethasone Dexamethasone is a fluorinated glucocorticoid medication used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye su ...

. The trial also showed that

Tocilizumab Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arter ...

further reduces the risk of death for the sickest patients with COVID-19. The trial found that a number of other treatments had no meaningful benefits for patients hospitalised with COVID-19, including

Hydroxychloroquine Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, an ...

Lopinavir/ritonavir Lopinavir/ritonavir (LPV/r), sold under the brand name Kaletra among others, is a fixed-dose combination antiretroviral medication for the treatment and prevention of HIV/AIDS. It combines lopinavir with a low dose of ritonavir. It is gene ...

Azithromycin Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. This includes otitis media, middle ear infections, strep throa ...

Convalescent plasma Convalescent plasma is the blood plasma collected from a survivor of an infectious disease. This plasma contains antibodies specific to a pathogen and can be used therapeutically by providing passive immunity when transfusing it to a newly infected ...

, and

Colchicine Colchicine is a medication used to prevent and treat gout, to treat familial Mediterranean fever and Behçet's disease, and to reduce the risk of myocardial infarction. The American College of Rheumatology recommends colchicine, nonstero ...

. The trial continues to study

REGN-COV2 Casirivimab/imdevimab, sold under the brand name REGEN‑COV among others, Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged. is a combination medici ...

and

Baricitinib Baricitinib, sold under the brand name Olumiant among others, is an immunomodulatory medication used for the treatment of rheumatoid arthritis, alopecia areata, and COVID-19. It acts as an inhibitor of janus kinase (JAK), blocking the subty ...

. He leads the Good Clinical Trials Collaborative, established by

Wellcome Trust The Wellcome Trust is a charitable foundation focused on health research based in London, United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of Burroughs Wellcome, one of the predec ...

Bill & Melinda Gates Foundation The Gates Foundation is an American private foundation founded by Bill Gates and Melinda French Gates. Based in Seattle, Washington, it was launched in 2000 and is reported to be the third largest charitable foundation in the world, holding $ ...

, and

African Academy of Sciences The African Academy of Sciences (AAS) is a non-aligned, non-political, not-for-profit, pan-African learned society formed in 1985. The AAS elects fellows ( FAAS) and affiliates. The AAS also awards the Obasanjo Prize for Scientific Discovery a ...

which seeks to develop and promote the adoption of new international guidelines for

s. He was previously one of the leaders of the Clinical Trial Transformation Initiative's risk-based monitoring, quality-by-design, and mobile clinical trial projects. He is an advocate of streamlined approaches to clinical trial design, delivery and regulation as a means to improve healthcare. He is founding director and chair of NHS DigiTrials, the Health Data Research Hub for Clinical Trials hosted by

NHS Digital NHS Digital was the trading name from 2016 of the Health and Social Care Information Centre, which was the national provider of information, data and IT systems for commissioners, analysts and clinicians in health and social care in England, p ...

, and leads the clinical trials theme for Health Data Research UK. In 2021, Landray was appointed to the Pandemic Preparedness Partnership (PPP), a group chaired by

Patrick Vallance Patrick John Thompson Vallance, Baron Vallance of Balham (born 17 March 1960), is a British physician, scientist, life peer, and clinical pharmacologist who has served as Minister of State for Science in the Department for Science, Innovatio ...

to advise the G7 presidency held by the

government A government is the system or group of people governing an organized community, generally a State (polity), state. In the case of its broad associative definition, government normally consists of legislature, executive (government), execu ...

Prime Minister A prime minister or chief of cabinet is the head of the cabinet and the leader of the ministers in the executive branch of government, often in a parliamentary or semi-presidential system. A prime minister is not the head of state, but r ...

Boris Johnson Alexander Boris de Pfeffel Johnson (born 19 June 1964) is a British politician and writer who served as Prime Minister of the United Kingdom and Leader of the Conservative Party (UK), Leader of the Conservative Party from 2019 to 2022. He wa ...

. He was

knighted A knight is a person granted an honorary title of a knighthood by a head of state (including the pope) or representative for service to the monarch, the church, or the country, especially in a military capacity. The concept of a knighthood ...

in the

2021 Birthday Honours The Queen's Birthday Honours for 2021 are appointments by some of the 16 Commonwealth realms of Queen Elizabeth II to various orders and honours to reward and highlight good works by citizens of those countries. The Birthday Honours are awarded ...

for services to public health and science.

Positions held

Landray holds the following positions: * Professor of Medicine & Epidemiology, Nuffield Department of Population Health, University of Oxford * Deputy Director, Big Data Institute, University of Oxford * Lead, Big Data & Computing Innovation, MRC Population Health Research Unit * Lead, Clinical Informatics & Big Data, NIHR Oxford Biomedical Research Centre * Honorary Consultant Physician, Oxford University Hospitals NHS Foundation Trust

References

External links

Martin Landray — Nuffield Department of Population Health

Martin Landray — Oxford Big Data Institute
{{DEFAULTSORT:Landray, Martin Academics of the University of Oxford British epidemiologists Living people Year of birth missing (living people) Knights Bachelor People educated at Abingdon School

Early life and education

Career

Positions held

See also

References

External links