The following is a list of notable software packages and applications licensed under an

open-source license An open-source license is a type of license for computer software and other products that allows the source code, blueprint or design to be used, modified and/or shared under defined terms and conditions. This allows end users and commercial compan ...

or in the

public domain The public domain (PD) consists of all the creative work to which no exclusive intellectual property rights apply. Those rights may have expired, been forfeited, expressly waived, or may be inapplicable. Because those rights have expired, ...

for use in the

health care Health care or healthcare is the improvement of health via the prevention, diagnosis, treatment, amelioration or cure of disease, illness, injury, and other physical and mental impairments in people. Health care is delivered by health ...

industry.

Public health and biosurveillance

Epi Info Epi Info is statistical software for epidemiology developed by Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia (US). Epi Info has been in existence for over 20 years and is currently available for Microsoft Windows, Androi ...

statistical software for epidemiology developed by

Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georg ...

. *

Spatiotemporal Epidemiological Modeler The Spatiotemporal Epidemiological Modeler (STEM) is free software available through the Eclipse Foundation. Originally developed by IBM Research, STEM is a framework and development tool designed to help scientists create and use spatial and t ...

is a tool, originally developed at

IBM Research IBM Research is the research and development division for IBM, an American multinational information technology company headquartered in Armonk, New York, with operations in over 170 countries. IBM Research is the largest industrial research or ...

, for modelings and visualizing the spread of infectious diseases. It is maintained by the

Eclipse Foundation The Eclipse Foundation AISBL is an independent, Europe-based not-for-profit corporation that acts as a steward of the Eclipse open source software development community, with legal jurisdiction in the European Union. It is an organization supp ...

and available under terms of the

Eclipse Public License The Eclipse Public License (EPL) is a free and open source software license most notably used for the Eclipse IDE and other projects by the Eclipse Foundation. It replaces the Common Public License (CPL) and removes certain terms relating to ...

Electronic records and medical practice management

Health system management

* iHRIS is an integrated Human Resource Information System developed by IntraHealth International under

USAID The United States Agency for International Development (USAID) is an Independent agencies of the United States government, independent agency of the federal government of the United States, U.S. federal government that is primarily responsible f ...

-funded CapacityPlus project and deployed in more than 20 countries in the world. iHRIS is distributed under the

GNU GPL The GNU General Public License (GNU GPL or simply GPL) is a series of widely used free software licenses that guarantee end users the four freedoms to run, study, share, and modify the software. The license was the first copyleft for general ...

. * DHIS is a district health management information system and data warehouse. DHIS2 is released under the

BSD license BSD licenses are a family of permissive free software licenses, imposing minimal restrictions on the use and distribution of covered software. This is in contrast to copyleft licenses, which have share-alike requirements. The original BSD li ...

. * HRHIS is a human resource for health information system for management of human resources for health developed by

University of Dar es Salaam The University of Dar es Salaam (UDSM) is a public university in Dar es Salaam, Tanzania. It was established in 1961 as an affiliate college of the University of London. The university became an affiliate of the University of East Africa (UEA) in 1 ...

college of information and communication technology, Department of Computer Science and Engineering, for Ministry of Health and Social Welfare (Tanzania) and funded by the Japan International Cooperation Agency (

JICA The is a governmental agency that delivers the bulk of Official Development Assistance (ODA) for the government of Japan. It is chartered with assisting economic and social growth in developing countries, and the promotion of international co ...

Disease management

* Breathing Games is a series of research-backed, co-created games to prevent, diagnose and treat chronic respiratory diseases. They are released under the Peer Production licence. *

Nightscout Nightscout is a free and open-source project, and associated social movement, that enables accessing and working with continuous glucose monitor (CGM) data. Nightscout software aims to give users access to their real time blood sugar data by ...

is a collection of software tools, including mobile clients, to enable DIY cloud-based

continuous glucose monitoring A continuous glucose monitor (CGM) is a device used for monitoring blood glucose on a continual basis by insulin-requiring people with diabetes, e.g. people with type I, type II diabetes or other types of diabetes (e.g. gestational diabetes). A c ...

"…for informational and educational purposes." Individual components are available under various open-source licenses, including the

GNU AGPL The GNU Affero General Public License (GNU AGPL) is a free, copyleft license published by the Free Software Foundation in November 2007, and based on the GNU General Public License, version 3 and the Affero General Public License. The Free So ...

MIT License The MIT License is a permissive free software license originating at the Massachusetts Institute of Technology (MIT) in the late 1980s. As a permissive license, it puts only very limited restriction on reuse and has, therefore, high license co ...

, and

Imaging/visualization

CamBA Camba is a word historically used in Bolivia to refer to the indigenous population in the eastern tropical region of the country, or to those born in the area of Santa Cruz, Beni, and Pando. Nowadays, the term "Camba" is used predominantly to ...

is a collection of

neuroimaging Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Incr ...

pipelines distributed under the

. * Drishti is a volumetric visualization package for viewing computer tomography data. Able to import DICOM image stacks. It is available under the

MIT license The MIT License is a permissive free software license originating at the Massachusetts Institute of Technology (MIT) in the late 1980s. As a permissive license, it puts only very limited restriction on reuse and has, therefore, high license co ...

. * Endrov Image and data viewer and editor. It is available under the

. *

GIMIAS GIMIAS is a workflow-oriented environment focused on biomedical image computing and simulation. The open-source framework is extensible through plug-ins and is focused on building research and clinical software prototypes. Gimias has been used t ...

is a workflow-oriented environment focused on biomedical image computing and simulation. It is available under a BSD-style license. *

Ginkgo CADx Ginkgo CADx is a multi platform (Windows, Linux, Mac OS X) DICOM viewer (*.dcm) and dicomizer (convert different files to DICOM). Ginkgo CADx is licensed under LGPL license, being an open source project with an Open core approach. The goal of Gin ...

Cross-platform open source DICOM viewer and dicomizer. It is available under the GNU LGPL. *

Insight Segmentation and Registration Toolkit __NOTOC__ ITK is a cross-platform, open-source application development framework widely used for the development of image segmentation and image registration programs. Segmentation is the process of identifying and classifying data found in a d ...

(ITK) v4.0+ is released under the Apache license. * InVesalius 3D medical imaging reconstruction software. It is available under the

. * ITK-SNAP Interactive software for 3D image navigation, annotation, and automatic segmentation. It is available under the

. * Orthanc – Lightweight, RESTful DICOM server for medical imaging. It is available under the

with

OpenSSL OpenSSL is a software library for applications that provide secure communications over computer networks against eavesdropping or need to identify the party at the other end. It is widely used by Internet servers, including the majority of HT ...

exception. * ParaView large-scale visualization tool. It is available under the

. *

3DSlicer 3D Slicer (Slicer) is a free and open source software package for image analysis and scientific visualization. Slicer is used in a variety of medical applications, including autism, multiple sclerosis, systemic lupus erythematosus, prostate ...

Platform for medical image visualization and algorithm development. DICOM support, segmentation and registration,

Diffusion MRI Diffusion-weighted magnetic resonance imaging (DWI or DW-MRI) is the use of specific MRI sequences as well as software that generates images from the resulting data that uses the diffusion of water molecules to generate contrast in MR images. It ...

processing, and image guided surgery support. It is available under a BSD-style license. * Voreen volume rendering engine—a library for visually exploring volume data sets. DICOM is supported and Voreen is used in medical visualization as well as for visualizing

electron microscopy An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a ...

data. It is available under the

. * VTK is a visualization toolkit available under the

. * Studierfenster (StudierFenster) is a free, non-commercial Open Science client/server-based Medical Imaging Processing (MIP) online framework.

Medical information systems

* Caisis is a web-based information system for the storage and analysis of cancer patient data intended to bridge the gap between clinic and research. It is available under the

. *

cTAKES Apache cTAKES: clinical Text Analysis and Knowledge Extraction System is an open-source Natural Language Processing (NLP) system that extracts clinical information from electronic health record unstructured data, unstructured text. It processes cl ...

(''"clinical Text Analysis Knowledge Extraction Software"'') is a

natural language processing Natural language processing (NLP) is an interdisciplinary subfield of linguistics, computer science, and artificial intelligence concerned with the interactions between computers and human language, in particular how to program computers to proc ...

system for extracting information from electronic medical record clinical free-text, an Apache top level project (TLP) since 2013, developed by the Mayo Clinic and others. It is available under the Apache license.

Research

Galaxy A galaxy is a system of stars, stellar remnants, interstellar gas, dust, dark matter, bound together by gravity. The word is derived from the Greek ' (), literally 'milky', a reference to the Milky Way galaxy that contains the Solar Sys ...

is a web platform for data-intensive biology using geographically-distributed supercomputers. * LabKey Server is an extensible platform for integrating, analyzing and sharing all types of biomedical research data. It provides secure, web-based access to research data and includes a customizable data processing pipeline. It is distributed under the Apache license.

Mobile devices

OpenAPS The Open Artificial Pancreas System (OpenAPS) project is a free and open-source project that aims to make basic artificial pancreas system (APS) technology available to everyone. The OpenAPS project was designed with the idea of quickly getting t ...

is a set of development tools and documentation to support a DIY implementation of an

artificial pancreas Automated insulin delivery systems are automated (or semi-automated) systems designed to assist people with diabetes, primarily type 1, by automatically adjusting insulin delivery to help them control their blood glucose levels. Currently availabl ...

for people with

Type 1 Diabetes Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system. Insulin is a hormone required for the cells to use blood sugar f ...

. Common setups include the interfacing of CGMs, Insulin Pumps, and

Raspberry Pi Raspberry Pi () is a series of small single-board computers (SBCs) developed in the United Kingdom by the Raspberry Pi Foundation in association with Broadcom. The Raspberry Pi project originally leaned towards the promotion of teaching basic ...

devices. It is released under the

, but compatible medical devices are proprietary. *

Ushahidi Ushahidi is an open source software application which utilises user-generated reports to collate and map data. It uses the concept of crowdsourcing serving as an initial model for what has been coined as "activist mapping" - the combination of ...

allows people to submit crisis information through

text messaging Text messaging, or texting, is the act of composing and sending electronic messages, typically consisting of alphabetic and numeric characters, between two or more users of mobile devices, desktops/ laptops, or another type of compatible compu ...

using a

mobile phone A mobile phone, cellular phone, cell phone, cellphone, handphone, hand phone or pocket phone, sometimes shortened to simply mobile, cell, or just phone, is a portable telephone that can make and receive telephone call, calls over a radio freq ...

, email or web form. Displays information in map view. It is released under the

GNU Affero General Public License The GNU Affero General Public License (GNU AGPL) is a free, copyleft license published by the Free Software Foundation in November 2007, and based on the GNU General Public License, version 3 and the Affero General Public License. The Free Sof ...

, but some libraries use different licenses.

Out-of-the-box distributions

* BioLinux *

Debian-Med A Debian Pure Blend is a project completely inside of Debian targeting a server or a desktop installation in very broad and general terms. A Debian Pure Blend aims to cover interests of specialised users, who might be children, lawyers, medical st ...

is a Debian Pure Blend for use in medical and biomedical settings. *

Ubuntu-Med Ubuntu-Med is collaborative medical education community linking medical schools, residency and fellowship programs in creating shared educational resources for physician and patient education. Packages Ubuntu-Med includes packages in the follo ...

Interoperability

* Mirth is an open source cross-platform

HL7 Health Level Seven or HL7 refers to a set of international standards for transfer of clinical and administrative data between software applications used by various healthcare providers. These standards focus on the application layer, which is "la ...

interface engine that enables bi-directional sending of HL7 messages between systems and applications over multiple transports. It is available under the

Mozilla Public License The Mozilla Public License (MPL) is a free and open-source weak copyleft license for most Mozilla Foundation software such as Firefox and Thunderbird The MPL license is developed and maintained by Mozilla, which seeks to balance the conce ...

Specifications

Continuity of Care Document The Continuity of Care Document (CCD) specification is an XML-based markup standard intended to specify the encoding, structure, and semantics of a patient summary clinical document for exchange. Structure The CCD specification is a constraint o ...

Fast Healthcare Interoperability Resources The Fast Healthcare Interoperability Resources' (FHIR, pronounced "fire") standard is a set of rules and specifications for exchanging electronic health care data. It is designed to be flexible and adaptable, so that it can be used in a wide rang ...

(FHIR) is a

Health Level 7 Health Level Seven or HL7 refers to a set of international standards for transfer of clinical and administrative data between software applications used by various healthcare providers. These standards focus on the application layer, which is "la ...

interoperability specification that defines

JSON JSON (JavaScript Object Notation, pronounced ; also ) is an open standard file format and data interchange format that uses human-readable text to store and transmit data objects consisting of attribute–value pairs and arrays (or other s ...

and

XML Extensible Markup Language (XML) is a markup language and file format for storing, transmitting, and reconstructing arbitrary data. It defines a set of rules for encoding documents in a format that is both human-readable and machine-readable. ...

data formats and a RESTful API. It is available under the CC0 license. *

openEHR openEHR is an open standard specification in health informatics that describes the management and storage, retrieval and exchange of health data in electronic health records (EHRs). In openEHR, all health data for a person is stored in a "one lifet ...

is an open standard specification in health informatics that describes the management and storage, retrieval and exchange of health data in electronic health records (EHRs) following a two-level modeling paradigm. The OpenEHR base specification is available under the

Creative Commons Creative Commons (CC) is an American non-profit organization and international network devoted to educational access and expanding the range of creative works available for others to build upon legally and to share. The organization has releas ...

Attribution-ShareAlike 3.0 Unported license.