The following is a list of notable software packages and applications licensed under an

open-source license Open-source licenses are software licenses that allow content to be used, modified, and shared. They facilitate free and open-source software (FOSS) development. Intellectual property (IP) laws restrict the modification and sharing of creative ...

or in the

public domain The public domain (PD) consists of all the creative work to which no Exclusive exclusive intellectual property rights apply. Those rights may have expired, been forfeited, expressly Waiver, waived, or may be inapplicable. Because no one holds ...

for use in the

health care Health care, or healthcare, is the improvement or maintenance of health via the preventive healthcare, prevention, diagnosis, therapy, treatment, wikt:amelioration, amelioration or cure of disease, illness, injury, and other disability, physic ...

industry.

Public health and biosurveillance

Epi Info Epi Info is statistical software for epidemiology developed by Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia (US). Epi Info has been in existence for over 20 years and is currently available for Microsoft Windows, Androi ...

statistical software for epidemiology developed by

Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the National public health institutes, national public health agency of the United States. It is a Federal agencies of the United States, United States federal agency under the United S ...

. *

Spatiotemporal Epidemiological Modeler The Spatiotemporal Epidemiological Modeler (STEM) is free software available through the Eclipse Foundation. Originally developed by IBM Research, STEM is a framework and development tool designed to help scientists create and use spatial an ...

is a tool, originally developed at

IBM Research IBM Research is the research and development division for IBM, an American Multinational corporation, multinational information technology company. IBM Research is headquartered at the Thomas J. Watson Research Center in Yorktown Heights, New York ...

, for modelings and visualizing the spread of infectious diseases. It is maintained by the

Eclipse Foundation The Eclipse Foundation AISBL is an independent, Europe-based not-for-profit organization that acts as a steward of the Eclipse open source software development community, with legal jurisdiction in the European Union. It is an organization supp ...

and available under terms of the

Eclipse Public License The Eclipse Public License (EPL) is a free and open source software license most notably used for the Eclipse IDE and other projects by the Eclipse Foundation. It replaces the Common Public License (CPL) and removes certain terms relating t ...

Electronic records and medical practice management

Health system management

* iHRIS is an integrated Human Resource Information System developed by

IntraHealth International IntraHealth International is a non-profit organization based in Chapel Hill, North Carolina, Chapel Hill, North Carolina, U.S.A. dedicated to working with Developing country, developing countries to improve their public health capabilities. Origina ...

under

USAID The United States Agency for International Development (USAID) is an agency of the United States government that has been responsible for administering civilian United States foreign aid, foreign aid and development assistance. Established in 19 ...

-funded CapacityPlus project and deployed in more than 20 countries in the world. iHRIS is distributed under the

GNU GPL The GNU General Public Licenses (GNU GPL or simply GPL) are a series of widely used free software licenses, or ''copyleft'' licenses, that guarantee end users the freedom to run, study, share, or modify the software. The GPL was the first ...

. * DHIS is a district health management information system and data warehouse. DHIS2 is released under the

BSD license BSD licenses are a family of permissive free software licenses, imposing minimal restrictions on the use and distribution of covered software. This is in contrast to copyleft licenses, which have share-alike requirements. The original BSD lic ...

. *

HRHIS A human resource for health information system (HRHIS), also known as human resource information system (HRIS) — is a system for collecting, processing, managing and disseminating data and information on human resource for health (HRH). Depending ...

is a human resource for health information system for management of human resources for health developed by

University of Dar es Salaam The University of Dar es Salaam (UDSM) (Swahili: ''Chuo Kikuu cha Dar es Salaam'') is a public university located in Ubungo District, Dar es Salaam Region, Tanzania. It was established in 1961 as an affiliate college of the University of London. ...

college of information and communication technology, Department of Computer Science and Engineering, for Ministry of Health and Social Welfare (Tanzania) and funded by the Japan International Cooperation Agency (

JICA The Japan International Cooperation Agency (), also known as JICA'','' is a governmental agency that delivers the bulk of Official Development Assistance (ODA) for the government of Japan. It is chartered with assisting economic and social gro ...

Disease management

* Breathing Games is a series of research-backed, co-created games to prevent, diagnose and treat chronic respiratory diseases. They are released under the Peer Production licence. * Nightscout is a collection of software tools, including mobile clients, to enable DIY cloud-based

continuous glucose monitoring A continuous glucose monitor (CGM) is a device for monitoring blood glucose continuously instead of monitoring periodically by drawing a drop of blood from a finger. This is known as continuous glucose monitoring. CGMs are used by people who trea ...

"…for informational and educational purposes." Individual components are available under various open-source licenses, including the

GNU AGPL The GNU Affero General Public License (GNU AGPL) is a free, copyleft license published by the Free Software Foundation in November 2007, and based on the GNU GPL version 3 and the ''Affero General Public License'' (non-GNU). It is intended for ...

MIT License The MIT License is a permissive software license originating at the Massachusetts Institute of Technology (MIT) in the late 1980s. As a permissive license, it puts very few restrictions on reuse and therefore has high license compatibility. Unl ...

, and

s. *

Tidepool A tide pool or rock pool is a shallow pool of seawater that forms on the rocky intertidal shore. These pools typically range from a few inches to a few feet deep and a few feet across. Many of these pools exist as separate bodies of water only ...

makes open-source tools to help people better manage diabetes. They have received FDA clearance for their Loop insulin dosing app.

Imaging/visualization

CamBA Camba is a word historically used in Bolivia to refer to the indigenous population in the eastern tropical region of the country, or to those born in the area of Santa Cruz, Beni, and Pando. Nowadays, the term "Camba" is used predominantly t ...

is a collection of

neuroimaging Neuroimaging is the use of quantitative (computational) techniques to study the neuroanatomy, structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive ...

pipelines distributed under the

. * Drishti is a volumetric visualization package for viewing computer tomography data. Able to import DICOM image stacks. It is available under the

MIT license The MIT License is a permissive software license originating at the Massachusetts Institute of Technology (MIT) in the late 1980s. As a permissive license, it puts very few restrictions on reuse and therefore has high license compatibility. Unl ...

. * Endrov Image and data viewer and editor. It is available under the

. * GIMIAS is a workflow-oriented environment focused on biomedical image computing and simulation. It is available under a BSD-style license. * Ginkgo CADx Cross-platform open source DICOM viewer and dicomizer. It is available under the

GNU LGPL The GNU Lesser General Public License (LGPL) is a free-software license published by the Free Software Foundation (FSF). The license allows developers and companies to use and integrate a software component released under the LGPL into their own ...

. *

Insight Segmentation and Registration Toolkit Insight is the understanding of a specific cause and effect within a particular context. The term insight can have several related meanings: *a piece of information *the act or result of understanding the inner nature of things or of seeing intu ...

(ITK) v4.0+ is released under the

Apache license The Apache License is a permissive free software license written by the Apache Software Foundation (ASF). It allows users to use the software for any purpose, to distribute it, to modify it, and to distribute modified versions of the software ...

. *

InVesalius InVesalius is a free medical software used to generate virtual reconstructions of structures in the human body. Based on two-dimensional images, acquired using computed tomography or magnetic resonance imaging equipment, the software generates v ...

3D medical imaging reconstruction software. It is available under the

. *

ITK-SNAP ITK-SNAP is an interactive software application that allows users to navigate three-dimensional medical images, manually delineate anatomical regions of interest, and perform automatic image segmentation. The software was designed with the audien ...

Interactive software for 3D image navigation, annotation, and automatic segmentation. It is available under the

. *

Orthanc In J. R. R. Tolkien's fantasy writings, Isengard () is a large fortress in Nan Curunír, the Wizard's Vale, in the western part of Middle-earth. In the fantasy world, the name of the fortress is described as a translation of Angrenost, a wo ...

– Lightweight,

RESTful REST (Representational State Transfer) is a software architectural style that was created to describe the design and guide the development of the architecture for the World Wide Web. REST defines a set of constraints for how the architecture of ...

DICOM server for medical imaging. It is available under the

GNU GPLv3 The GNU General Public Licenses (GNU GPL or simply GPL) are a series of widely used free software licenses, or ''copyleft'' licenses, that guarantee end users the freedom to run, study, share, or modify the software. The GPL was the first c ...

. *

ParaView ParaView is an open-source multiple-platform application for interactive, scientific visualization. It has a client–server architecture to facilitate remote visualization of datasets, and generates level of detail (LOD) models to maintain in ...

large-scale visualization tool. It is available under the

. *

3DSlicer 3D Slicer (Slicer) is a free and open source software package for image analysis and scientific visualization. Slicer is used in a variety of medical applications, including autism, multiple sclerosis, systemic lupus erythematosus, prostate can ...

Platform for medical image visualization and algorithm development. DICOM support, segmentation and registration,

Diffusion MRI Diffusion-weighted magnetic resonance imaging (DWI or DW-MRI) is the use of specific MRI sequences as well as software that generates images from the resulting data that uses the diffusion of water molecules to generate contrast (vision), contrast ...

processing, and image guided surgery support. It is available under a BSD-style license. *

Voreen Voreen (''vo''lume ''re''ndering ''en''gine) is an open-source software, open-source volume visualization library and development platform. Through the use of GPU-based volume rendering techniques it allows high frame rates on standard graphics h ...

volume rendering engine—a library for visually exploring volume data sets. DICOM is supported and Voreen is used in medical visualization as well as for visualizing

electron microscopy An electron microscope is a microscope that uses a beam of electrons as a source of illumination. It uses electron optics that are analogous to the glass lenses of an optical light microscope to control the electron beam, for instance focusing i ...

data. It is available under the

. *

VTK The Visualization Toolkit (VTK) is a free software system for 3D computer graphics, image processing and scientific visualization.''Visualization Handbook'', Academic Press, 2005, Chapter 30: the Visualization Toolkit/ref> VTK is distributed und ...

is a visualization toolkit available under the

. * Studierfenster (StudierFenster) is a free, non-commercial Open Science client/server-based Medical Imaging Processing (MIP) online framework. *

Medical open network for AI Medical open network for AI (MONAI) is an Open-source software, open-source, community-supported Framework Computer, framework for Deep learning (DL) in Health care, healthcare imaging. MONAI provides a collection of domain-optimized implementatio ...

is a framework for

Deep learning Deep learning is a subset of machine learning that focuses on utilizing multilayered neural networks to perform tasks such as classification, regression, and representation learning. The field takes inspiration from biological neuroscience a ...

in healthcare imaging that is open-source available under the

Apache Licence The Apache License is a permissive free software license written by the Apache Software Foundation (ASF). It allows users to use the software for any purpose, to distribute it, to modify it, and to distribute modified versions of the software u ...

and supported by the community.

Medical information systems

* Caisis is a web-based information system for the storage and analysis of cancer patient data intended to bridge the gap between clinic and research. It is available under the

. *

cTAKES Apache cTAKES: clinical Text Analysis and Knowledge Extraction System is an open-source Natural Language Processing (NLP) system that extracts clinical information from electronic health record unstructured text. It processes clinical notes, iden ...

(''"clinical Text Analysis Knowledge Extraction Software"'') is a

natural language processing Natural language processing (NLP) is a subfield of computer science and especially artificial intelligence. It is primarily concerned with providing computers with the ability to process data encoded in natural language and is thus closely related ...

system for extracting information from electronic medical record clinical free-text, an

Apache The Apache ( ) are several Southern Athabaskan language-speaking peoples of the Southwestern United States, Southwest, the Southern Plains and Northern Mexico. They are linguistically related to the Navajo. They migrated from the Athabascan ho ...

top level project (TLP) since 2013, developed by the

Mayo Clinic Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science ...

and others. It is available under the

Research

Galaxy A galaxy is a Physical system, system of stars, stellar remnants, interstellar medium, interstellar gas, cosmic dust, dust, and dark matter bound together by gravity. The word is derived from the Ancient Greek, Greek ' (), literally 'milky', ...

is a web platform for data-intensive biology using geographically-distributed supercomputers. * LabKey Server is an extensible platform for integrating, analyzing and sharing all types of biomedical research data. It provides secure, web-based access to research data and includes a customizable data processing

pipeline A pipeline is a system of Pipe (fluid conveyance), pipes for long-distance transportation of a liquid or gas, typically to a market area for consumption. The latest data from 2014 gives a total of slightly less than of pipeline in 120 countries ...

. It is distributed under the

Mobile devices

Source: * OpenAPS is a set of development tools and documentation to support a DIY implementation of an

artificial pancreas Automated insulin delivery systems are automated (or semi-automated) systems designed to assist people with insulin-requiring diabetes, by automatically adjusting insulin delivery in response to blood glucose levels. Currently available systems ...

for people with

Type 1 Diabetes Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that occurs when the body's immune system destroys pancreatic cells (beta cells). In healthy persons, beta cells produce insulin. Insulin is a hormone require ...

. Common setups include the interfacing of CGMs,

Insulin Pumps An insulin pump is a medical device used for the administration of insulin in the treatment of diabetes mellitus, also known as continuous subcutaneous insulin therapy. The device configuration may vary depending on design. A traditional pu ...

, and

Raspberry Pi Raspberry Pi ( ) is a series of small single-board computers (SBCs) developed in the United Kingdom by the Raspberry Pi Foundation in collaboration with Broadcom Inc., Broadcom. To commercialize the product and support its growing demand, the ...

devices. It is released under the

, but compatible medical devices are proprietary. *

Ushahidi Ushahidi is an open source software application that collates and maps data using user-generated reports. It uses the concept of crowdsourcing serving as an initial model for what has been coined as "activist mapping" – the combination of soc ...

allows people to submit crisis information through

text messaging Text messaging, or texting, is the act of composing and sending electronic messages, typically consisting of alphabetic and numeric characters, between two or more users of mobile phones, tablet computers, smartwatches, desktops/laptops, or ...

using a

mobile phone A mobile phone or cell phone is a portable telephone that allows users to make and receive calls over a radio frequency link while moving within a designated telephone service area, unlike fixed-location phones ( landline phones). This rad ...

, email or web form. Displays information in map view. It is released under the

GNU Affero General Public License The GNU Affero General Public License (GNU AGPL) is a free, copyleft license published by the Free Software Foundation in November 2007, and based on the GNU GPL version 3 and the ''Affero General Public License'' (non-GNU). It is intended fo ...

, but some libraries use different licenses.

Out-of-the-box distributions

* BioLinux * Debian-Med is a

Debian Pure Blend A Debian Pure Blend is a project completely inside of Debian targeting a server or a desktop installation in very broad and general terms. A Debian Pure Blend aims to cover interests of specialised users, who might be children, lawyers, medical st ...

for use in medical and biomedical settings. * Ubuntu-Med

Interoperability

* Mirth is an open source cross-platform HL7 interface engine that enables bi-directional sending of HL7 messages between systems and applications over multiple transports. It is available under the

Mozilla Public License The Mozilla Public License (MPL) is a free and open-source weak copyleft license for most Mozilla Foundation software such as Firefox and Thunderbird. The MPL is developed and maintained by Mozilla, which seeks to balance the concerns of bo ...

Specifications

Continuity of Care Document The Continuity of Care Document (CCD) specification is an XML-based markup standard intended to specify the encoding, structure, and semantics of a patient summary clinical document for exchange. Structure The CCD specification is a constraint o ...

Fast Healthcare Interoperability Resources The Fast Healthcare Interoperability Resources (FHIR, , like ''fire'') standard is a set of rules and specifications for the secure exchange of electronic health care data. It is designed to be flexible and adaptable, so that it can be used in a ...

(FHIR) is a

Health Level 7 Health Level Seven, abbreviated to HL7, is a range of global standards for the transfer of clinical and administrative health data between applications with the aim to improve patient outcomes and health system performance. The HL7 standards focu ...

interoperability specification that defines

JSON JSON (JavaScript Object Notation, pronounced or ) is an open standard file format and electronic data interchange, data interchange format that uses Human-readable medium and data, human-readable text to store and transmit data objects consi ...

and

XML Extensible Markup Language (XML) is a markup language and file format for storing, transmitting, and reconstructing data. It defines a set of rules for encoding electronic document, documents in a format that is both human-readable and Machine-r ...

data formats and a

API An application programming interface (API) is a connection between computers or between computer programs. It is a type of software interface, offering a service to other pieces of software. A document or standard that describes how to build ...

. It is available under the CC0 license. *

openEHR openEHR is an open standard specification in health informatics that describes the management and storage, retrieval and exchange of health data in electronic health records (EHRs). In openEHR, all health data for a person is stored in a "one lifet ...

is an open standard specification in health informatics that describes the management and storage, retrieval and exchange of health data in electronic health records (EHRs) following a two-level modeling paradigm. The OpenEHR base specification is available under the

Creative Commons Creative Commons (CC) is an American non-profit organization and international network devoted to educational access and expanding the range of creative works available for others to build upon legally and to share. The organization has release ...

Attribution-ShareAlike 3.0 Unported license.