Kenneth Kaushansky (born October 20, 1953) is an American medical doctor,

hematologist Hematology ( spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the production ...

, former editor of the medical journal ''

Blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...

'', and served as the

dean Dean may refer to: People * Dean (given name) * Dean (surname), a surname of Anglo-Saxon English origin * Dean (South Korean singer), a stage name for singer Kwon Hyuk * Dean Delannoit, a Belgian singer most known by the mononym Dean * Dean Sw ...

of the Stony Brook University School of Medicine from 2010 to 2021. Prior to moving to Stony Brook, he was the Helen M. Ranney Professor, and chair of the department of medicine at

University of California, San Diego School of Medicine The University of California, San Diego School of Medicine is the graduate medical school of the University of California, San Diego, a public land-grant research university in La Jolla, California. It was the third medical school in the Univer ...

Early life and education

Kaushansky was born on October 20, 1953, in

Montreal Montreal is the List of towns in Quebec, largest city in the Provinces and territories of Canada, province of Quebec, the List of the largest municipalities in Canada by population, second-largest in Canada, and the List of North American cit ...

Quebec Quebec is Canada's List of Canadian provinces and territories by area, largest province by area. Located in Central Canada, the province shares borders with the provinces of Ontario to the west, Newfoundland and Labrador to the northeast, ...

, Canada. His father, who "always wanted to be an American", migrated with the family to the United States when Kaushansky was two years old. Kaushansky graduated from

UCLA The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California, United States. Its academic roots were established in 1881 as a normal school then known as the southern branch of the C ...

in 1975,

summa cum laude Latin honors are a system of Latin phrases used in some colleges and universities to indicate the level of distinction with which an academic degree has been earned. The system is primarily used in the United States. It is also used in some Sout ...

and

Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States. It was founded in 1776 at the College of William & Mary in Virginia. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, ...

with a B.S. in

biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

. He stayed at UCLA to obtain his

medical degree A medical degree is a professional degree admitted to those who have passed coursework in the fields of medicine and/or surgery from an accredited medical school. Obtaining a degree in medicine allows for the recipient to continue on into special ...

in 1979. It was here that he met his future wife Lauren who was also at the time enrolled as a student at UCLA. As he left to join the

University of Washington The University of Washington (UW and informally U-Dub or U Dub) is a public research university in Seattle, Washington, United States. Founded in 1861, the University of Washington is one of the oldest universities on the West Coast of the Uni ...

Seattle Seattle ( ) is the most populous city in the U.S. state of Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the 18th-most populous city in the United States. The city is the cou ...

to complete his internship and

residency Residency may refer to: * Artist-in-residence, a program to sponsor the residence and work of visual artists, writers, musicians, etc. * Concert residency, a series of concerts performed at one venue * Domicile (law), the act of establishing or m ...

, Lauren enrolled for a master's in education at

Antioch University Antioch University is a private university with multiple campuses in the United States and online programs. It is the continuation of Antioch College, which was founded in 1852. Antioch College's first president was politician, abolitionist, and ...

in Seattle. Kaushansky was appointed

Chief Resident Residency or postgraduate training is a stage of graduate medical education. It refers to a qualified physician (one who holds the degree of MD, DO, MBBS/MBChB), veterinarian ( DVM/VMD, BVSc/BVMS), dentist ( DDS or DMD), podiatrist ( DPM), op ...

at the Swedish Medical Center in

Seattle, Washington Seattle ( ) is the List of municipalities in Washington, most populous city in the U.S. state of Washington (state), Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the List of Unit ...

, in 1982. Describing himself as a "biochemist at heart", Kaushansky fell in love with

hematology Hematology (American and British English spelling differences#ae and oe, spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to bloo ...

during his second year of residency. Curious about blood diseases and disorders, he chose to focus on the field during his

fellowship A fellow is a title and form of address for distinguished, learned, or skilled individuals in academia, medicine, research, and industry. The exact meaning of the term differs in each field. In learned or professional societies, the term refers ...

between 1982 and 1986 at the

. His decision to pursue

was also influenced by the persuasive arguments of Dr. Clement Finch, the then Chief of

Hematology Hematology (American and British English spelling differences#ae and oe, spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to bloo ...

at the University of Washington, who said "there is no other discipline in medicine where we know more about the

of disease than in hematology". In a Q&A session with the

American Society of Hematology The American Society of Hematology (ASH) is a professional organization representing hematologists, founded in 1958. Its annual meeting is held in December of every year and has attracted more than 30,000 attendees. The society publishes the medi ...

, Kaushansky recalled: During his time in Seattle, he was honored with the

NIH The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...

Physician Scientist Award in 1984, given to promising physician-scientists early in their careers. He was also awarded the junior faculty award by the

American Cancer Society The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society w ...

and was elected a member of the

American Society for Clinical Investigation The American Society for Clinical Investigation (ASCI), established in 1908, is one of the oldest and most respected medical honor societies in the United States. Organization and purpose The ASCI is an honorary society to which more than 2,800 p ...

and the

Association of American Physicians The Association of American Physicians (AAP) is an honorary medical society founded in 1885 by the Canadian physician Sir William Osler and six other distinguished physicians of his era for "the advancement of scientific and practical medicine ...

. In 2002, Kaushansky was appointed as Chair and Helen M. Ranney Professor of the Department of Medicine at the University of California, San Diego. The Helen Ranney Chair in Medicine was the first research chair at the medical school named after a professor, the first endowed chair funded by the faculty, and the first endowed chair at UCSD named in honor of a woman professor. Helen Margaret Ranney was the first female president of

, and her landmark research established one of the earliest links between genetic factors and

sickle cell disease Sickle cell disease (SCD), also simply called sickle cell, is a group of inherited Hemoglobinopathy, haemoglobin-related blood disorders. The most common type is known as sickle cell anemia. Sickle cell anemia results in an abnormality in the ...

. On her demise in April 2010, Kaushansky (who had known her through his work in medical research) wrote, "Helen's career was marked by her intelligent approach to both clinical and research issues, her ability to achieve and inspire greatness, and her incredible wit". Between 2003 and 2009, Kaushansky was named on the list of America's Top Doctors and

San Diego San Diego ( , ) is a city on the Pacific coast of Southern California, adjacent to the Mexico–United States border. With a population of over 1.4 million, it is the List of United States cities by population, eighth-most populous city in t ...

's Top Doctors in

Internal Medicine Internal medicine, also known as general medicine in Commonwealth nations, is a medical specialty for medical doctors focused on the prevention, diagnosis, and treatment of diseases in adults. Its namesake stems from "treatment of diseases of ...

. In 2004, he was also elected a member to the prestigious

Institute of Medicine The National Academy of Medicine (NAM), known as the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineerin ...

of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

. Kaushansky is a past president of the American Society of Hematology (2007-2008), the American Society for Clinical Investigation (2004–2005) and the Western Society for Clinical Investigation (1998–1999). He also served a five-year term as Editor-in-Chief of the journal Blood (1998-2002) and as a major reviewer for the National Institutes of Health and many major scientific periodicals. Kaushansky has been recognized for his scientific and clinical contributions by election as a Master of the

American College of Physicians The American College of Physicians (ACP) is a Philadelphia-based national organization of internal medicine physicians, who specialize in the diagnosis, treatment, and care of adults. With 161,000 members, ACP is the largest medical-specialty or ...

, and to several honor societies and organizations, including the American Society for Clinical Investigation, the Association of American Physicians, the Institute of Medicine of the National Academies of Science and the American Academy of Arts and Sciences.

Work and research

From 2010 to 2021, Kaushansky was the senior vice president for health sciences and the

of Stony Brook Medicine. He succeeded Dr. Richard N. Fine, who announced his intent to return to practicing pediatric nephrology in 2009. As dean and senior VP, Kaushansky oversaw the education, clinical and research components of the school of medicine and the health sciences, which include the school of dental medicine, school of health technology and management, school of nursing and the school of social welfare. He also had some oversight responsibility for Stony Brook University Medical Center, and oversight for the Long Island State Veterans Home. With 25 academic departments, 21 residency training programs and 27 fellowship training programs at Stony Brook Medicine, and as part of the only academic medical center on

Long Island Long Island is a densely populated continental island in southeastern New York (state), New York state, extending into the Atlantic Ocean. It constitutes a significant share of the New York metropolitan area in both population and land are ...

, Kaushansky increased enrollment to help meet a growing need for physicians nationwide and welcomed 124 men and women to the class of 2012 – the largest incoming class ever. Stony Brook Medicine is also home to a $4 million, 6,000 square-feet Clinical Skills Center, a state-of-the art training center where medical students evaluate and diagnose patients through teaching modules that incorporate the use of actor patients and computerized mannequins that simulate characteristic disease conditions. Kaushansky's appointment at Stony Brook was lauded by several academicians such as

Eric W. Kaler Eric William Kaler (born 1956) is an American chemical engineer and university administrator. He has served as the president of Case Western Reserve University since 2021. From 2011 to 2019, Kaler was president of the University of Minnesota. He ...

the then provost and vice-president of Brookhaven Affairs at

Stony Brook University Stony Brook University (SBU), officially the State University of New York at Stony Brook, is a public university, public research university in Stony Brook, New York, United States, on Long Island. Along with the University at Buffalo, it is on ...

and Dr. Edward J. Benz, the president of the

Dana–Farber Cancer Institute Dana–Farber Cancer Institute (DFCI) is a comprehensive cancer treatment and research center in Boston, Massachusetts. Dana-Farber is the founding member of the Dana-Farber/Harvard Cancer Center, Harvard's Comprehensive Cancer Center designated ...

and past president of the

and the

. Kaushansky's lab at Stony Brook focuses on hematopoietic growth factors and the regulation of their

gene expression Gene expression is the process (including its Regulation of gene expression, regulation) by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, ...

. The lab also runs several projects to understand the physiology of megakaryotic developments and the tools necessary to perform

gene therapy Gene therapy is Health technology, medical technology that aims to produce a therapeutic effect through the manipulation of gene expression or through altering the biological properties of living cells. The first attempt at modifying human DNA ...

for bleeding disorders. Kaushansky has conducted seminal research on the molecular biology of blood cell production. As reported in journals such as ''

Nature Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...

'' and ''

The New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. Founded in 1812, the journal is among the most prestigious peer-reviewed medical journals. Its 2023 impact factor w ...

'', his team has cloned several of the genes important in the growth and differentiation of blood cells, including

thrombopoietin Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the ''THPO'' gene. Thrombopoietin is a glycoprotein hormone produced by the liver and kidney which regulates the pro ...

, a key regulator of

stem cell In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell ...

and

platelet Platelets or thrombocytes () are a part of blood whose function (along with the coagulation#Coagulation factors, coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a thrombus, blood clot. Platelets have no ...

production. Thrombopoietin is the powerful

hormone A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physio ...

that the body uses to direct the

bone marrow Bone marrow is a semi-solid biological tissue, tissue found within the Spongy bone, spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It i ...

to produce platelets, the disk-like cells that are necessary for blood to clot. In June 1994, the ''

New York Times ''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of ...

'' reported that Kaushansky along with a team from

ZymoGenetics ZymoGenetics, Inc was one of the oldest biotechnology/pharmaceutical companies in the USA, based in Seattle, Washington. The company was involved in the development of therapeutic proteins. Located on Lake Union, the address of the ZymoGenetics ...

had found the mouse

gene, cloned it, produced recombinant hormone, demonstrated that it worked as expected in mice and then found the human hormone by looking for a human gene that resembled the mouse gene. In recent years his group has established that

exerts a profound influence on

hematopoietic stem cell Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within the ...

s, affects the expression of a number of

transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of genetics, genetic information from DNA to messenger RNA, by binding t ...

s that influence stem cell fate decisions (

HOXB4 Homeobox protein Hox-B4 is a protein that in humans is encoded by the ''HOXB4'' gene. Function This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of h ...

HOXA9 Homeobox protein Hox-A9 is a protein that in humans is encoded by the ''HOXA9'' gene. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromos ...

, c-Myb,

HIF1A Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the ''HIF1A'' gene. The Nobel Prize in Physiology or Medicine 2019 was awa ...

) and has unraveled the pathobiology of several

congenital disorder A birth defect is an abnormal condition that is present at childbirth, birth, regardless of its cause. Birth defects may result in disability, disabilities that may be physical disability, physical, intellectual disability, intellectual, or dev ...

s of

thrombopoiesis Thrombopoiesis is the formation of thrombocytes (blood platelets) in the bone marrow. Thrombopoietin is the main regulator of thrombopoiesis. Thrombopoietin affects most aspects of the production of platelets. This includes self-renewal and expa ...

. Kaushansky served as the

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The editor-in-chief heads all departments of the organization and is held accoun ...

of the medical journal ''

'' for five years between 1997 and 2002. Just before assuming this position, he was awarded the William Dameshek Prize.

William Dameshek William Dameshek (1900 in Voronezh – 1969) was an American hematologist. He graduated from Harvard College and Harvard Medical School and spent the early part of his career at Beth Israel Hospital (now Beth Israel Deaconess Medical Center). He w ...

was the founder of ''Blood'' and a renowned

. The Dameshek Prize is awarded annually to someone less than 50 years of age, who is deemed to have made "outstanding contributions" to hematology. In 2006 and 2007, Kaushansky was elected as a member the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

, and honored as a Master of the

. He is also the former president of the

and the

Personal life

Kaushansky is married t
Lauren Elizabeth Kaushansky
and together they have two children, Alexis and Joshua Kaushansky. Alexis is a

PhD A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...

molecular biologist Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactio ...

and Joshua is an

economist An economist is a professional and practitioner in the social sciences, social science discipline of economics. The individual may also study, develop, and apply theories and concepts from economics and write about economic policy. Within this ...

for the

Massachusetts Department of Public Utilities The Massachusetts Department of Public Utilities is one of two Public Utilities Commissions of the Massachusetts, Commonwealth of Massachusetts, in the Massachusetts Executive Office of Energy and Environmental Affairs, Executive Office of Energy ...

based in

Boston Boston is the capital and most populous city in the Commonwealth (U.S. state), Commonwealth of Massachusetts in the United States. The city serves as the cultural and Financial centre, financial center of New England, a region of the Northeas ...

. Kaushansky and his wife reside in

Eatons Neck, New York Eatons Neck is a hamlet and census-designated place (CDP) in the Town of Huntington in Suffolk County, on the North Shore of Long Island, in New York, United States. The population was 1,406 at the 2010 census. There is a United States Coast G ...

Patents awarded

* US Patent #5,546,536: Inventors: Kaushansky K, Hagen FS. Colony-stimulating factor derivatives. 1988 * US Patent # 5,989,537: Inventors: Holly RD, Lok S, Foster DC, Kaushansky K, Kuijper JL, Lofton-Day CE, Oort PJ. Methods for stimulating granulocyte-macrophage lineage using thrombopoietin. 1999 * US Patent #6,099,830: Inventors: Kaushansky K. Methods for stimulating erythropoiesis using hematopoietic proteins. August 8, 2000 * Australian Patent #725159: Inventor: Kaushansky K. Methods for stimulating erythropoiesis using thrombopoietin. October 5, 2000 * Australian Patent #723793: Inventors: Holly RD, Lok S, Foster DC, Hagen FS, Kaushansky K, Kuijper JL, Lofton-Day CE, Oort PJ, Burkhead SK. Hematopoietic protein and materials and methods for making it. December 21, 2000 * US Patent #6,316,254: Inventors: Holly RD, Lok S, Foster DC, Kaushansky K, Kuijper JL, Lofton-Day CE, Oort PJ. Methods for stimulating erythropoiesis using hematopoietic proteins. November 13, 2001 * International Patent # WO 2004/026332A1: Kaushansky K, MacDonald B. Methods of increasing platelet and hematopoietic stem cell production. April 1, 2004.

Selected publications

* Kaushansky K, Lok S, Holly RD, Broudy VC, Lin N, Bailey MC, Forstrom JW, Buddle M, Oort PJ, Hagen FS, Roth GJ, Papayannopoulou Th, Foster DC: Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand

. ''

'' 369:568-571, 1994. * Lok S, Kaushansky K, Holly RD, Kuijper JL, Lofton-Day CE, Oort PJ, Grant FJ, Heipel MD, Burkhead SK, Kramer JM, Bell LA, Sprecher CA, Blumberg H, Johnson R, Prunkard D, Ching AFT, Mathewes S, Bailey MC, Forstrom JW, Buddle MM, Osborn SG, Evans SJ, Sheppard PO, Presnell SR, O'Hara PJ, Hagen FS, Roth GJ., Foster DC: Cloning and expression of murine

cDNA In genetics, complementary DNA (cDNA) is DNA that was reverse transcribed (via reverse transcriptase) from an RNA (e.g., messenger RNA or microRNA). cDNA exists in both single-stranded and double-stranded forms and in both natural and engin ...

and stimulation of platelet production in vivo. ''

'' 369:565-568, 1994. * Kaushansky K, Broudy VC, Lin N, Jorgensen MJ, McCarty J, Fox N, Zucker-Franklin D, Lofton-Day C:

Thrombopoietin Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the ''THPO'' gene. Thrombopoietin is a glycoprotein hormone produced by the liver and kidney which regulates the pro ...

, the Mpl-ligand, is essential for full

megakaryocyte A megakaryocyte () is a large bone marrow cell with a lobation, lobated nucleus that produces blood platelets (thrombocytes), which are necessary for normal blood coagulation, clotting. In humans, megakaryocytes usually account for 1 out of 10,00 ...

development. ''

Proc. Natl. Acad. Sci. USA ''Proceedings of the National Academy of Sciences of the United States of America'' (often abbreviated ''PNAS'' or ''PNAS USA'') is a peer-reviewed multidisciplinary scientific journal. It is the official journal of the National Academy of Scien ...

'' 92:3234-3238, 1995. * Kaushansky K, Broudy, VC, Grossmann A, Humes J, Lin N, Ren H-P, Bailey MC, Papayannopoulou Th, Forstrom JW, Sprugel KH:

expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy. '' J. Clin. Invest.'' 96:1683-1687, 1995. * Fero ML, Rivkin M, Tasch M, Porter P, Carow CE, Firpo E, Polyak K, Tsai LH, Broudy VC, Perlmutter R, Kaushansky K, Roberts JM: A syndrome of gigantism, tumorigenesis and female sterility in p27Kip-1 deficient mice. ''

Cell Cell most often refers to: * Cell (biology), the functional basic unit of life * Cellphone, a phone connected to a cellular network * Clandestine cell, a penetration-resistant form of a secret or outlawed organization * Electrochemical cell, a de ...

''. 85:733-744, 1996. * Kaushansky K, Shoemaker SG, O'Rork C, McCarty J: The regulation of GM-CSF is dependent on a complex interplay of multiple nuclear regulatory proteins. Mol. Immunol. 33: 461–470, 1996. * Kaushansky K: Thrombopoietin. Drug Therapy Series. ''

'' 339:746-754, 1998 * Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper J, Kramer J, Conklin D, Presnell SR, Berry J, Shiota F, Bort S, Hambly K, Mudri S, Clegg C, Moore M, Grant FJ, Lofton-Day C, Gilbert T, Raymond F, Ching A, Yao L, Smith D, Webster P, Whitmore T, Maurer M, Kaushansky K, Holly R, Foster D. Interleukin 21 and IL21R: A novel

cytokine Cytokines () are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Cytokines are produced by a broad range of cells, including immune cells like macrophages, B cell, B lymphocytes, T cell, T lymphocytes ...

-receptor pair involved in NK cell expansion and

lymphocyte A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), an ...

function. ''

'' 408: 57-63, 2000 * Geddis AE, Kaushansky K. Endomitotic megakaryocytes form a midzone in

anaphase Anaphase () is the stage of mitosis after the process of metaphase, when replicated chromosomes are split and the newly-copied chromosomes (daughter chromatids) are moved to opposite poles of the cell. Chromosomes also reach their overall maxim ...

but have a deficiency in cleavage furrow formation. ''

Cell Cycle The cell cycle, or cell-division cycle, is the sequential series of events that take place in a cell (biology), cell that causes it to divide into two daughter cells. These events include the growth of the cell, duplication of its DNA (DNA re ...

''. 2006; 5:538-545 * Kaushansky K. Lineage specific hematopoietic growth factors. ''

'' 354:2034-2045, 2006 * Geron I, Abrahamsson A, Kavalerchik E, Barroga C, Gotlib J, Hood J, Soll R, Noronha G, Durocher J, Tefferi A, Kaushansky K, Jamieson C. Selective inhibition of JAK2 driven

erythroid Red blood cells (RBCs), referred to as erythrocytes (, with -''cyte'' translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cel ...

differentiation potential of

polycythemia Polycythemia (also known as polycythaemia) is a laboratory finding in which the hematocrit (the volume percentage of red blood cells in the blood) and/or hemoglobin concentration are increased in the blood. Polycythemia is sometimes called erythr ...

vera progenitors. ''

Cancer Cell Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells. Cell division is a normal process used by the body for growth and repair. A parent cell divides to form two daughter cells, an ...

'', 2008; 13:321-330 * Hitchcock I, Chen M, Fox NE, Kaushansky K. YRRL motifs in the cytoplasmic domain of the thrombopoietin receptor regulate receptor internalization and degradation. ''

'' 2008 112:2222-2231 * Soda M, Willert K, Kaushansky K, Geddis A. Inhibition of GSK-3a promotes survival and proliferation of megakaryocytic cells through b-catenin-independent signaling. Cell Signal. 2008 20:2317-2323 * Kaushansky K: Thrombopoietin: Biological and preclinical properties. ''

Leukemia Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' ...

'' 10:Suppl. S46-48, 1996 * Kaushansky K, Lok S: The molecular and cellular biology of thrombopoietin, the MPL ligand. In: Molecular Basis of Thrombosis and Hemostatis. KA High, HR Roberts (Eds.), Marcel Dekker, Inc., New York, NY pp. 651-662, 1995. * Kaushansky K: In vitro predictions, in vivo realities. ''

Platelets Platelets or thrombocytes () are a part of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a blood clot. Platelets have no cell nucleus; they are fragments of cyto ...

'' 8: 444–445, 1997.

References

{{DEFAULTSORT:Kaushansky, Kenneth 1953 births Living people 21st-century American physicians American biochemists American medical researchers Canadian emigrants to the United States American hematologists Anglophone Quebec people Canadian hematologists Fellows of the American Academy of Arts and Sciences Medical educators Members of the National Academy of Medicine Physicians from Montreal Stony Brook University faculty University of California, San Diego faculty University of California, Los Angeles alumni David Geffen School of Medicine at UCLA alumni Presidents of the American Society of Hematology