ZymoGenetics
ZymoGenetics, Inc was one of the oldest biotechnology/pharmaceutical companies in the USA, based in Seattle, Washington. The company was involved in the development of therapeutic proteins. Located on Lake Union, the address of the ZymoGenetics headquarters was 1201 Eastlake Avenue East. It was closed in 2019 after its acquisition by Bristol Myers Squibb. The company was founded in 1981 by Professors Earl W. Davie and Benjamin D. Hall of the University of Washington and 1993 Nobel Laureate in Chemistry Michael Smith of the University of British Columbia. Initially named Zymos, the company was forced to change its name to ZymoGenetics under threat of trademark infringement from the similarly named semiconductor company ZyMOS. Soon after its founding, ZymoGenetics began working on recombinant proteins with Danish company Novo Nordisk, and was acquired by that company in 1988. It was spun off as a public company in 2000. Bristol-Myers Squibb acquired the company in 2010 f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Earl Davie
Earl Warren Davie (October 25, 1927 - June 6, 2020) was an American biochemist. He was a professor emeritus of biochemistry at the University of Washington. Davie studied the blood proteins involved in coagulation and was among the first scientists to describe the steps of the clotting process. He was a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences. Early life Davie was born on October 25, 1927, in Tacoma, Washington, to Charles and Teckla Davie. He grew up in La Grande, Washington and attended Eatonville High School. He received an undergraduate degree in 1950 from the University of Washington, where he had worked in the laboratory of biochemistry professor Donald Hanahan. He completed a Ph.D. at UW in 1954. During his doctoral studies, Davie worked with Hans Neurath to learn about protein structure and function. Career After a postdoctoral fellowship with Fritz Lipmann at Harvard Medical School, Davie worked at the Case ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bristol-Myers Squibb
The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company. Headquartered in Princeton, New Jersey, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the largest U.S. corporations. For fiscal 2022, it had a total revenue of $46.2 billion. Bristol Myers Squibb manufactures prescription pharmaceuticals and biologics in several therapeutic areas, including cancer, HIV/AIDS, cardiovascular disease, diabetes, hepatitis, rheumatoid arthritis, and psychiatric disorders. BMS's primary research and development (R&D) sites are located in Lawrence, New Jersey (formerly Squibb, near Princeton), Summit, New Jersey, formerly HQ of Celgene, New Brunswick, New Jersey; Redwood City, California; and Seville in Spain, with other sites in Devens and Cambridge, Massachusetts; Braine-l'Alleud, Belgium; Tokyo, Japan; Hyderabad; Bangalore, India and Wirr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Michael Smith (chemist)
Michael Smith (April 26, 1932 – October 4, 2000) was a British-born Canadian biochemist and businessman. He shared the 1993 Nobel Prize in Chemistry with Kary Mullis for his work in developing site-directed mutagenesis. Following a PhD in 1956 from the University of Manchester, he undertook postdoctoral research with Har Gobind Khorana (himself a Nobel Prize winner) at the British Columbia Research Council in Vancouver, British Columbia, Canada. Subsequently, Smith worked at the Fisheries Research Board of Canada Laboratory in Vancouver before being appointed a professor of biochemistry in the UBC Faculty of Medicine in 1966. Smith's career included roles as the founding director of the UBC Biotechnology Laboratory (1987 to 1995) and the founding scientific leader of the Protein Engineering Network of Centres of Excellence (PENCE). In 1996 he was named Peter Wall Distinguished Professor of Biotechnology. Subsequently, he became the founding director of the Genome Sequencing ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Seattle
Seattle ( ) is the most populous city in the U.S. state of Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the 18th-most populous city in the United States. The city is the county seat of King County, the most populous county in Washington. The Seattle metropolitan area's population is 4.02 million, making it the 15th-most populous in the United States. Its growth rate of 21.1% between 2010 and 2020 made it one of the country's fastest-growing large cities. Seattle is situated on an isthmus between Puget Sound, an inlet of the Pacific Ocean, and Lake Washington. It is the northernmost major city in the United States, located about south of the Canadian border. A gateway for trade with East Asia, the Port of Seattle is the fourth-largest port in North America in terms of container handling . The Seattle area has been inhabited by Native Americans (such as the Duwamish, who had at least 17 villages a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fred Hutchinson Cancer Research Center
The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington (state), Washington. History The center grew out of the Pacific Northwest Diabetes Research Institute, Pacific Northwest Research Foundation, founded in 1956 by William B. Hutchinson (physician), William B. Hutchinson (1909–1997). The Foundation was dedicated to the study of heart surgery, cancer, and diseases of the endocrine system. Hutchinson's younger brother Fred Hutchinson, Fred (1919–1964) was a Major League Baseball, major league pitcher and Manager (baseball), manager who died of lung cancer at age 45. The next year, William Hutchinson established the Fred Hutchinson Cancer Research Center as a division of the Pacific Northwest Research Foundation.Louis Fiset, December 30, 2004 for HistoryLink: The Free, Online Encyclopedia of Washington State HistorHutchi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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President (corporate Title)
A president is a leader of an organization, company, community, club, trade union, university or other group. The relationship between a president and a chief executive officer varies, depending on the structure of the specific organization. In a similar vein to a chief operating officer, the title of corporate president as a separate Job, position (as opposed to being combined with a "Corporate title#Senior management, C-suite" designation, such as "president and chief executive officer" or "president and chief operating officer") is also loosely Definition, defined; the president is usually the legally Legal recognition, recognized highest rank of Corporate title, corporate officer, ranking above the various Vice president#In business, vice presidents (including senior vice president and executive vice president), but on its own generally considered Hierarchy, subordinate, in practice, to the CEO. The powers of a president vary widely across organizations and such powers come fr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Seattle Genetics
SeaGen was the world's first large scale commercial tidal stream generator. It was four times more powerful than any other tidal stream generator in the world at the time of installation. It was decommissioned by SIMEC Atlantis Energy Limited in summer 2019, having exported 11.6 GWh to the grid since 2008. The first SeaGen generator was installed in Strangford Narrows between Strangford and Portaferry in Northern Ireland. Strangford Lough was also the site of the first known tide mill in the world, the Nendrum Monastery mill where remains dating from 787 CE have been excavated. History Marine Current Turbines, the developer of SeaGen, demonstrated its first prototype of a tidal stream generator in 1994 with a 15 kilowatt system in Loch Linnhe, off the west coast of Scotland. In May 2003, the prototype for SeaGen, '', was installed off the coast of Lynmouth, North Devon, England. Seaflow was a single rotor turbine which generated 300 kW but was not c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bothell, Washington
Bothell () is a city in King and Snohomish counties in the U.S. state of Washington. It is part of the Seattle metropolitan area, situated near the northeast end of Lake Washington in the Eastside region. It had a population of 48,161 residents as of the 2020 census. The city lies along the Sammamish River, the historic home of the indigenous Sammamish people, and is adjacent to Kenmore and Woodinville. It was established in 1870 and platted by David Bothell and his family in 1888, shortly before the arrival of railroads in the area. The town was incorporated in 1909 and originally relied on logging and farming; in the mid-20th century, it became a bedroom community for workers commuting to Seattle and later other Eastside cities. Interstate 405 connects the city to other areas of the Eastside and functions as a bypass of Seattle. Bothell's modern economy is centered around biotechnology and high-tech companies that have facilities that were developed in the late 20th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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ZyMOS
ZyMOS Corporation (its name a partial acronym for Zirconium Metal Oxide Semiconductors), later Appian Technology, Inc., was a semiconductor manufacturing company located in Sunnyvale, California. It initially designed and manufactured custom and semi-custom integrated circuits. After the introduction of the IBM PC in the early 1980s, there was strong customer demand for ICs to support the production of IBM PC-AT clones. In 1987, Appian responded to this demand by developing the POACH (PC-On-A-Chip) peripheral series, one of the first chipsets of its kind, enabling manufacturers of PC AT clones to simplify PC motherboard designs and reduce cost and time to market. Intel soon licensed this chipset to support Intel 80286 sales. Intel second-sourced to Zymos Corp. of these 82230/82231 High Integration AT-Compatible Chip Set.Ormsby, John, Editor, "New Product Focus: Components: Intel's 82X3X Chip-set Handles Logic Functions That Once Required The Services Of Sources Of Chips", In ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Public Utility
A public utility company (usually just utility) is an organization that maintains the infrastructure for a public service (often also providing a service using that infrastructure). Public utilities are subject to forms of public control and regulation ranging from local community-based groups to statewide government monopolies. Public utilities are meant to supply goods and services that are considered essential; water, gas, electricity, telephone, waste disposal, and other communication systems represent much of the public utility market. The transmission lines used in the transportation of electricity, or natural gas pipelines, have natural monopoly characteristics. A monopoly can occur when it finds the best way to minimize its costs through economies of scale to the point where other companies cannot compete with it. For example, if many companies are already offering electricity, the additional installation of a power plant will only disadvantage the consumer ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chief Executive Officer
A chief executive officer (CEO), also known as a chief executive or managing director, is the top-ranking corporate officer charged with the management of an organization, usually a company or a nonprofit organization. CEOs find roles in various organizations, including public and private corporations, Nonprofit organization, nonprofit organizations, and even some government organizations (notably state-owned enterprises). The governor and CEO of a corporation or company typically reports to the board of directors and is charged with maximizing the value of the business, which may include maximizing the profitability, market share, revenue, or another financial metric. In the nonprofit and government sector, CEOs typically aim at achieving outcomes related to the organization's mission, usually provided by legislation. CEOs are also frequently assigned the role of the main manager of the organization and the highest-ranking officer in the C-suite. Origins The term "chief executi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Seattle City Light
Seattle City Light is the public utility providing electricity to Seattle, Washington, in the United States, and parts of its metropolitan area, including all of Shoreline, nearly all of Lake Forest Park, and parts of unincorporated King County, Burien, Normandy Park, SeaTac, Renton, and Tukwila. Seattle City Light is the 10th largest public utility in the United States and the first municipal utility in the US to own and operate a hydroelectric facility. In 2005, it became the first electric utility in the United States to fully offset all its carbon emissions and has remained carbon neutral every year since. Seattle City Light is a department of the City of Seattle and is governed by the Economic Development, Technology & City Light committee of the Seattle City Council. Overview Approximately 961,000 residents (493,663 metered customers) are served by Seattle City Light in its service area, which covers in Seattle and surrounding areas. They collectively used 9,317,8 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |