Karl Lennert
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Karl Lennert, M.D. (4 June 1921 – 27 August 2012) was a German
physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
and
pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
.


Early life and education

Lennert was born in
Fürth Fürth (; East Franconian German, East Franconian: ; ) is a List of cities and towns in Germany, city in northern Bavaria, Germany, in the administrative division (''Regierungsbezirk'') of Middle Franconia. It is the Franconia#Towns and cities, s ...
, which is now contiguous with
Nuremberg Nuremberg (, ; ; in the local East Franconian dialect: ''Nämberch'' ) is the Franconia#Towns and cities, largest city in Franconia, the List of cities in Bavaria by population, second-largest city in the States of Germany, German state of Bav ...
, in
Bavaria Bavaria, officially the Free State of Bavaria, is a States of Germany, state in the southeast of Germany. With an area of , it is the list of German states by area, largest German state by land area, comprising approximately 1/5 of the total l ...
. After graduating from high school there, Karl attended medical school from 1939 to 1945 at the Friedrich-Alexander Universitat of
Erlangen Erlangen (; , ) is a Middle Franconian city in Bavaria, Germany. It is the seat of the administrative district Erlangen-Höchstadt (former administrative district Erlangen), and with 119,810 inhabitants (as of 30 September 2024), it is the smalle ...
(now the
University of Erlangen-Nuremberg A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Univ ...
). After World War II, Lennert remained in Erlangen until 1950 as a resident physician in the Institute of Pathology. After another year of postgraduate study at the
Max Planck Institute The Max Planck Society for the Advancement of Science (; abbreviated MPG) is a formally independent non-governmental and non-profit association of German research institutes. Founded in 1911 as the Kaiser Wilhelm Society, it was renamed to the M ...
for Biophysical Chemistry in
Göttingen Göttingen (, ; ; ) is a college town, university city in Lower Saxony, central Germany, the Capital (political), capital of Göttingen (district), the eponymous district. The River Leine runs through it. According to the 2022 German census, t ...
, he joined the department of pathology at Johann Wolfgang Goethe University in
Frankfurt Frankfurt am Main () is the most populous city in the States of Germany, German state of Hesse. Its 773,068 inhabitants as of 2022 make it the List of cities in Germany by population, fifth-most populous city in Germany. Located in the forela ...
-am-Main. There, under the direction of Professor Arnold Lauche, he began his lifelong study of hematopoietic diseases, with emphasis on malignant
lymphoma Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). The name typically refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enlarged lymph node ...
s.


Career

In 1963, Lennert was asked to chair the Institute of Pathology at Christian-Albrechts-University (CAU) in Kiel. This was a prestigious appointment, because at that time, 75% of department chairs at CAU were the sons of prominent Professors of Medicine in Germany. His students included Reza Parwaresch, Martin-Leo Hansmann, H.J. Radzun, Alfred Feller, Hans-Konrad Müller-Hermelink, and Peter M. Banks. Lennert worked closely with clinicians in the Collaborative Research Centre 111 of the
German Research Foundation The German Research Foundation ( ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germany. In 2019, the DFG had a funding bud ...
, principally represented by Drs. Arnulf Thiede and Wolfram Sterry. Lennert was the founding president of the European Association of Hematopathology. In 1989 he became a Professor Emeritus in Kiel.


Kiel Classification System for Lymphomas

Around 1975, Lennert began work on a system of nosological classification for malignant lymph node tumors (non-Hodgkin lymphomas) that was predicated on the cytomorphological and biochemical attributes of developing lymphoid cells. It was meant to supplement or supersede other schemes that were existence at that time, including the Lukes-Collins system and the Rappaport classification. Lennert's paradigm quickly gained traction among pathologists in Europe and became known as the "Kiel classification". Later, other systems of nosology for malignant lymphoma were introduced, including the Revised European American Lymphoma Classification (REAL) scheme in 1994, and the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
system of 2001, which are now preferentially in clinical use. Dr. Lennert is also recognized for first describing a variant of
peripheral T-cell lymphoma Peripheral T-cell lymphoma refers to a group of T-cell lymphomas that develop away from the thymus or bone marrow. Examples include: * Cutaneous T-cell lymphomas * Angioimmunoblastic T-cell lymphoma * Extranodal natural killer/T-cell lymphoma, ...
in 1952, which he termed "lymphoepithelioid lymphoma." It is now commonly and eponymously called " Lennert lymphoma" or "Lennert's lymphoma." In total, Lennert contributed over 300 scholarly papers and 4 textbooks to the medical literature during his working life. Lennert accumulated a large and unique teaching archive of lymphoma cases in his department at Kiel. He had developed a personal-professional relationship with
Uwe Barschel Uwe Barschel (13 May 1944 – 11 October 1987) was a German politician of the Christian Democratic Union (CDU) who served as Minister-President of Schleswig-Holstein from 1982 to 1987. Barschel resigned as Minister-President shortly after he ...
, a prominent West German politician in the 1980s, and Barschel assured him that funds would be supplied to preserve the archive in a special institute at the time of Lennert's retirement. However, the politician was involved in a scandal in 1987 and he died at that time under questionable circumstances; hence, his promise to Dr. Lennert was never fulfilled.


Honors and awards

Lennert received several professional honors and awards during his long career. These included election to membership of the
German Academy of Sciences Leopoldina The German National Academy of Sciences Leopoldina (), in short Leopoldina, is the national academy of Germany, and is located in Halle (Saale). Founded on 1 January 1652, based on academic models in Italy, it was originally named the ''Academi ...
in 1966; the Schleiden Medal; the Robert Koch Medal; the Rudolf Virchow Medal and the
Ernst Jung Prize The Ernst Jung Prize is a prize awarded annually for excellence in biomedical sciences. The Ernst Jung Foundation, funded by Hamburg merchant Ernst Jung in 1967, has awarded the Ernst Jung Prize in Medicine, now €300,000, since 1976, and the lif ...
. Lennert also received honorary doctorates from Friedrich-Alexander Universitat, the Ghent University, the University of Madrid, and the University of Köln. He was a fellow of the
Norwegian Academy of Science and Letters The Norwegian Academy of Science and Letters (, DNVA) is a learned society based in Oslo, Norway. Its purpose is to support the advancement of science and scholarship in Norway. History The Royal Frederick University in Christiania was establis ...
from 1986.


Personal life

Dr. Lennert was married to another physician, Dr. Amanda Heyer. They had a daughter, Monika (married name Boske), who is also a physician in Wurzburg, Germany.


References

{{DEFAULTSORT:Lennert, Karl German pathologists 1921 births 2012 deaths People from Fürth Physicians from Kiel University of Erlangen–Nuremberg alumni Schleiden Medal recipients Members of the Norwegian Academy of Science and Letters