John Rodman Paul
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John Rodman Paul (April 18, 1893 – May 6, 1971) was an American
virologist Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, the ...
whose research focused on the spread of
polio Poliomyelitis ( ), commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 75% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe ...
and the development of treatments for the disease.


Life and achievements

Paul was born on April 18, 1893, in
Philadelphia Philadelphia ( ), colloquially referred to as Philly, is the List of municipalities in Pennsylvania, most populous city in the U.S. state of Pennsylvania and the List of United States cities by population, sixth-most populous city in the Unit ...
. He earned his
undergraduate degree An undergraduate degree (also called first degree or simply degree) is a colloquial term for an academic degree earned by a person who has completed undergraduate courses. In the United States, it is usually offered at an institution of higher ed ...
in 1915 from
Princeton University Princeton University is a private university, private Ivy League research university in Princeton, New Jersey, United States. Founded in 1746 in Elizabeth, New Jersey, Elizabeth as the College of New Jersey, Princeton is the List of Colonial ...
and received his medical training at
Johns Hopkins School of Medicine The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Established in 1893 following the construction of the Johns Hopkins Hospital, th ...
, which awarded him an M.D. degree.Staff
"Dr. John Paul, Polio Researcher, Dies"
''
The New York Times ''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of ...
'', May 7, 1971. Accessed September 27, 2010.
He began his career as an assistant pathologist at Johns Hopkins in 1919 and 1920, and followed that with an
internship An internship is a period of work experience offered by an organization for a limited period of time. Once confined to medical graduates, internship is used to practice for a wide range of placements in businesses, non-profit organizations and g ...
at
Pennsylvania Hospital Pennsylvania Hospital is a Private hospital, private, non-profit, 515-bed teaching hospital located at 800 Spruce Street (Philadelphia), Spruce Street in Center City, Philadelphia, Center City Philadelphia, The hospital was founded on May 11, 17 ...
in Philadelphia from 1920 to 1922. In 1928, Paul joined the faculty of the
Yale School of Medicine The Yale School of Medicine is the medical school of Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. It is the sixth-oldest m ...
as a professor of
internal medicine Internal medicine, also known as general medicine in Commonwealth nations, is a medical specialty for medical doctors focused on the prevention, diagnosis, and treatment of diseases in adults. Its namesake stems from "treatment of diseases of ...
and held the position of professor of
preventive medicine Preventive healthcare, or prophylaxis, is the application of healthcare measures to prevent diseases.Hugh R. Leavell and E. Gurney Clark as "the science and art of preventing disease, prolonging life, and promoting physical and mental health a ...
starting in 1940, which he retained until his retirement. Paul established the Yale Poliomyelitis Study Unit in 1931 together with James D. Trask, advancing the concept of "clinical epidemiology" in which the path of disease outbreaks in small communities was directly studied. Together with Trask, Paul received the first grant from the National Foundation for Infantile Paralysis (better known as the
March of Dimes March of Dimes is a United States nonprofit organization that works to improve the health of mothers and babies. The organization was founded by US President Franklin D. Roosevelt in 1938, as the National Foundation for Infantile Paralysis, to co ...
), which was renewed each year for another 30 years. As part of the study unit, Paul went to
Middletown, Connecticut Middletown is a city in Middlesex County, Connecticut, United States. Located along the Connecticut River, in the central part of the state, 16 miles (25.749504 km) south of Hartford, Connecticut, Hartford. Middletown is the largest city in the L ...
and New Haven into neighborhoods where polio was spreading and collected samples from patients in an effort to understand how the virus spread. Paul's team found that
poliovirus Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species '' Enterovirus C'', in the family of '' Picornaviridae''. There are three poliovirus serotypes, numbered 1, 2, and 3. Poliovirus is composed ...
was excreted by people afflicted with the condition and could be found in sewage in areas that had experienced outbreaks. In a 1951 article published in ''The New York Times Magazine'' in 1951, Paul noted the improvements that had been made in treating and relieving pain in those afflicted with polio, but lamented the lack of progress in prevention of polio. He travelled to the
Soviet Union The Union of Soviet Socialist Republics. (USSR), commonly known as the Soviet Union, was a List of former transcontinental countries#Since 1700, transcontinental country that spanned much of Eurasia from 1922 until Dissolution of the Soviet ...
in 1956 as part of a group of five doctors who visited medical facilities there. Paul's research also included work on
hepatitis Hepatitis is inflammation of the liver parenchyma, liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), Anorexia (symptom), poor appetite ...
,
infectious mononucleosis Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). Most people are infected by the virus as children, when the disease produces few or no symptoms. In young adu ...
and
rheumatic fever Rheumatic fever (RF) is an inflammation#Disorders, inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a Streptococcal pharyngitis, streptococcal throat infection. Si ...
. After his retirement from the medical school in 1961, he continued to lecture on the history of medicine. Paul became a professor emeritus in 1961 and until 1966, served as the director of the World Health Organization Serum Reference Bank located in the Yale Department of Epidemiology at the Yale School of Public Health. As a member of the polio advisory committee of the
United States Public Health Service The United States Public Health Service (USPHS or PHS) is a collection of agencies of the Department of Health and Human Services which manages public health, containing nine out of the department's twelve operating divisions. The assistant s ...
, Paul joined in a 1962 recommendation that the use of an oral polio vaccine created by
Albert B. Sabin Albert Bruce Sabin ( ; born Abram Saperstejn; August 26, 1906 – March 3, 1993) was a Polish-American medical researcher, best known for developing the oral polio vaccine, which has played a key role in nearly eradicating the disease. In 1969 ...
in treating adults should be halted based on the lack of clinical evidence showing that the vaccine prevented those receiving the vaccine from developing the disease. In his 1971 book ''A History of Poliomyelitis'', Paul put forth the proposition that humans had always been exposed to
poliovirus Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species '' Enterovirus C'', in the family of '' Picornaviridae''. There are three poliovirus serotypes, numbered 1, 2, and 3. Poliovirus is composed ...
but had been protected by antibodies contained in the mothers milk, and that it was the clean water, sewer systems and improved hygiene of modern civilization that prevented children from being exposed to the virus at an early age, hypothesizing that protection would be conferred if people were exposed to the virus as infants. Orent, Wendy
"Still a Scourge"
, ''proto: Dispatches from the Frontiers of Medicine'',
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood of Boston, Massachusetts. It is the original and largest clinical education and research facility of Harvard Medical School/Harvar ...
. Spring 2006. Accessed September 27, 2010.
A resident of the
New Haven, Connecticut New Haven is a city of the U.S. state of Connecticut. It is located on New Haven Harbor on the northern shore of Long Island Sound. With a population of 135,081 as determined by the 2020 United States census, 2020 U.S. census, New Haven is List ...
suburb of Guilford, Paul died at age 78 on May 6, 1971, at
Yale – New Haven Hospital Yale New Haven Hospital (YNHH) is a 1,541-bed hospital located in New Haven, Connecticut. It is the second-largest hospital in the United States and one of the largest in the world. It is the primary teaching hospital for the Yale School of Med ...
after what ''
The New York Times ''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of ...
'' described in his obituary as a "long illness".


Publications

A complete list of Paul's numerous publications can be found in the NAS publication by Horstmann and Beeson pp. 347−368 * ''A History of Poliomyelitis''. New Haven: Yale University Press, 1971.


Awards

* 1945: Member of the
United States National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
* 1946:
Medal of Freedom The Presidential Medal of Freedom is the highest civilian award of the United States, alongside the Congressional Gold Medal. It is an award bestowed by decision of the president of the United States to "any person recommended to the President ...
* 1946:
Charles V. Chapin Charles Value Chapin (January 17, 1856 – January 31, 1941) was an American pioneer in public health research and practice during the Progressive Era. He was superintendent of health for Providence, Rhode Island between 1884 and 1932. He es ...
Award * 1950: Honorary member of the
Royal Society of Medicine The Royal Society of Medicine (RSM) is a medical society based at 1 Wimpole Street, London, UK. It is a registered charity, with admission through membership. Its Chief Executive is Michele Acton. History The Royal Society of Medicine (R ...
in London * 1954: The Howard T. Rickets Award * 1958: Inducted into the
Polio Hall of Fame The Polio Hall of Fame (or the Polio Wall of Fame) consists of a linear grouping of sculptured busts of fifteen scientists and two laymen who made important contributions to the knowledge and treatment of poliomyelitis. It is found on the outside w ...
in
Warm Springs, Georgia Warm Springs is a city in Meriwether County, Georgia, United States. The population was 465 at the 2020 census. History Warm Springs, originally named "Bullochville" (after the Bulloch family, which began after Stephen Bullock moved to Meriw ...
Epidemiology and Public Health at Yale: A Yale Tercentennial Exhibit
,
Yale School of Public Health The Yale School of Public Health (YSPH) was founded in 1915 by Charles-Edward Amory Winslow and is one of the oldest public health masters programs in the United States. YSPH is both a department (established in 1915) within the school of medic ...
. Accessed September 27, 2010.
* 1963:
Kober Medal The George M. Kober Medal and Lectureship are two different awards by the Association of American Physicians (AAP) in honor of one of its early presidents, George M. Kober. The George M. Kober Lectureship, is an honor given to an AAP member "for o ...
by the
Association of American Physicians The Association of American Physicians (AAP) is an honorary medical society founded in 1885 by the Canadian physician Sir William Osler and six other distinguished physicians of his era for "the advancement of scientific and practical medicine ...


References


Further reading

* Dorothy M. Horstmann, Paul B. Beeson: ''John Rodman Paul, 1893−1971, A biographical memoir'', published by The National Academy of Sciences, Washington D.C, 1975; also onlin
PDF
{{DEFAULTSORT:Paul, John R. 1893 births 1971 deaths American virologists Johns Hopkins School of Medicine alumni Members of the United States National Academy of Sciences People from Guilford, Connecticut Scientists from Philadelphia Recipients of the Medal of Freedom Princeton University alumni Yale School of Medicine faculty