John Fraser (educator)
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Sir John Fraser, 1st Baronet, (23 March 1885 – 1 December 1947) was Regius Professor of Clinical Surgery at Edinburgh University from 1925 to 1944 and served as principal of the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
from 1944 to 1947. His study of
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
in children was to disprove the view of the Nobel prize winner
Robert Koch Heinrich Hermann Robert Koch ( ; ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he i ...
that bovine tuberculosis did not play a major pathogenic role in human disease. The subsequent legislation led to the elimination of tuberculosis from milk supplies and resulted in a decline in incidence of bone and joint tuberculosis in children. In 1940 he was the first surgeon in Britain to ligate an uninfected
patent ductus arteriosus Patent ductus arteriosus (PDA) is a medical condition in which the ''ductus arteriosus'' fails to close after childbirth, birth: this allows a portion of oxygenated blood from the left heart to flow back to the lungs from the aorta, which has a h ...
.


Early life and family

Fraser, whose parents both came from families of farmers, was born 23 March 1885 in
Tain Tain ( ) is a royal burgh and parish in the County of Ross, in the Scottish Highlands, Highlands of Scotland. Etymology The name derives from the nearby River Tain, the name of which comes from an Indo-European root meaning 'flow'. The Gaelic n ...
,
Rosshire Ross-shire (; ), or the County of Ross, was a county in the Scottish Highlands. It bordered Sutherland to the north and Inverness-shire to the south, as well as having a complex border with Cromartyshire, a county consisting of numerous enclav ...
. He was a few months old when his father died and he was raised as an only child by his mother. He went on to attend
Tain Royal Academy Tain Royal Academy is a secondary school in Highland, Scotland. The school first opened in 1813, with a new building opened in 1969 and an educational campus currently being built, due to open in 2025. Tain Royal Academy is part of the Golspie, ...
. He then studied medicine, gaining admission to the medical faculty at the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
in 1902, graduating
MB ChB A Bachelor of Medicine, Bachelor of Surgery (; MBBS, also abbreviated as BM BS, MB ChB, MB BCh, or MB BChir) is a medical degree granted by medical schools or universities in countries that adhere to the United Kingdom's higher education tradi ...
with honours in 1907, winning the Allan Fellowship in Clinical Medicine and the gold medal for Clinical Surgery."Sir John Fraser", ''The Times'', 4 December 1947, p 6. Fraser's son, Sir James Fraser, also became a surgeon and president of the Royal College of Surgeons of Edinburgh.


Early medical career

Fraser served as house surgeon, first in the
Royal Infirmary of Edinburgh The Royal Infirmary of Edinburgh (RIE) was established in 1729, and is the oldest voluntary hospital in Scotland. The new buildings of 1879 were claimed to be the largest voluntary hospital in the United Kingdom, and later on, the Empire."In Com ...
and then at the Royal Hospital for Sick Children under Sir Harold Stiles, who was to have a powerful influence on Fraser's approach to surgical problems and scientific enquiry. He became a fellow of the Royal College of Surgeons of Edinburgh (FRCSEd) in 1910. Fraser's scientific approach was manifest in his ChM dissertation, nominally on inguinal hernia in childhood but containing a detailed account of the descent of the testis which was based on 1000 cases he studied and which contained many original observations. The dissertation was awarded the Lister Prize for surgery.


Research into tuberculosis

For his MD thesis he studied the pathology and aetiology of tuberculosis of bones and joints. As Stiles had treated bone and joint TB in children by radical excision there was a large pathological collection available for study. He set out to investigate the claim by
Robert Koch Heinrich Hermann Robert Koch ( ; ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he i ...
that the risk of humans acquiring TB by drinking milk from tuberculous cows was negligible. This view was not supported by laboratory experiments commissioned by a British royal commission. Fraser disproved Koch's view by demonstrating that 60% of the bones and joints he examined had the bovine form of the causative organism, ''
Mycobacterium bovis ''Mycobacterium bovis'' is a slow-growing (16- to 20-hour generation time) Aerobic organism, aerobic bacterium and the causative agent of tuberculosis in cattle (known as bovine TB). It is related to ''Mycobacterium tuberculosis'', the bacterium ...
''. He went on to demonstrate the organism in local milk supplies and called for widespread
pasteurisation In food processing, pasteurization ( also pasteurisation) is a process of food preservation in which packaged foods (e.g., milk and fruit juices) are treated with mild heat, usually to less than , to eliminate pathogens and extend shelf life ...
of milk with increased regulation. The subsequent legislation led to the elimination of tuberculosis from milk supplies and resulted in a decline in incidence of bone and joint tuberculosis in children. Fraser's 1912 MD thesis was awarded a gold medal.


First World War

Fraser was commissioned in the
Royal Army Medical Corps The Royal Army Medical Corps (RAMC) was a specialist corps in the British Army which provided medical services to all Army personnel and their families, in war and in peace. On 15 November 2024, the corps was amalgamated with the Royal Army De ...
(RAMC) in August 1914. He served on the Western Front as Regimental Medical Officer in the First Cavalry Division and then, as surgeon to a casualty clearing station, he treated the wounded from the
Battle of Loos The Battle of Loos took place from 1915 in France on the Western Front (World War I), Western Front, during the First World War. It was the biggest British attack of 1915, the first time that the British used Chemical weapons in World War I, ...
. In 1916 he was wounded, was
mentioned in dispatches To be mentioned in dispatches (or despatches) describes a member of the armed forces whose name appears in an official report written by a superior officer and sent to the high command, in which their gallant or meritorious action in the face of t ...
and received the
Military Cross The Military Cross (MC) is the third-level (second-level until 1993) military decoration awarded to officers and (since 1993) Other ranks (UK), other ranks of the British Armed Forces, and formerly awarded to officers of other Commonwealth of ...
. During this wartime service, he wrote papers on treatment of abdominal wounds, on the treatment of gas gangrene with Eusol (a solution of
hypochlorous acid Hypochlorous acid is an inorganic compound with the chemical formula , also written as HClO, HOCl, or ClHO. Its structure is . It is an acid that forms when chlorine dissolves in water, and itself partially dissociates, forming a hypochlorite an ...
) and on shock and its treatment with gum saline and other intravenous infusions. His studies on blood pressure in shock resulted in his being invited to join the Medical Research Committee's small group on surgical shock whose other members included distinguished physiologists like E H Starling, W M Bayliss and the future Nobel laureates C S Sherrington and Henry Dale. Fraser's wartime observations were a major contribution to this committee who were to pioneer the scientific basis of fluid replacement in surgical shock. While an army surgeon, he was successful in stitching up a gunshot wound of a heart. He produced a book with Cuthbert Wallace about his medical experiences during the war, ''Surgery at a Casualty Clearing Station'', which was published by A & C Black in 1918. Many of the illustrations were produced by Fraser's wife.


Post-war medical career

On his return to Edinburgh, he was appointed surgeon to the Royal Hospital for Sick Children and the Royal Infirmary. In 1924 he was appointed to the Regius Chair of Clinical Surgery in succession to Sir Harold Stiles. He was elected a member of the
Harveian Society of Edinburgh The Harveian Society of Edinburgh was founded in April 1782 by Andrew Duncan (physician, born 1744), Andrew Duncan. The Society holds an annual Festival in honour of the life and works of William Harvey, the physician who first correctly des ...
. He was elected a fellow of the
Royal Society of Edinburgh The Royal Society of Edinburgh (RSE) is Scotland's national academy of science and letters. It is a registered charity that operates on a wholly independent and non-partisan basis and provides public benefit throughout Scotland. It was establis ...
in 1928, his proposers being
Arthur Logan Turner Arthur Logan Turner FRCSEd FRSE LLD (4 May 1865 – 6 June 1939) was a Scottish surgeon, who specialised in diseases of ear, nose and throat (ENT) and was one of the first surgeons to work at the purpose-built ENT Pavilion at the Royal Infirmary ...
,
Harold Stiles Sir Harold Jalland Stiles (21 March 1863 – 19 April 1946) was an English surgeon who was known for his research into cancer and tuberculosis and for treatment of nerve injuries. Early years Harold Stiles was born in Spalding, Lincolnsh ...
, Arthur Robinson,
James Hartley Ashworth James Hartley Ashworth (2 May 1874 – 4 February 1936) was a British marine zoologist. Life See He was born on 2, May 1874, in Accrington in Lancashire, the only son of James Ashworth. He spent most of his early life in Burnley, attending t ...
and Sir James Alfred Ewing. In 1935, he left London for Southampton and on to New York on board the RMS 'Aquitania' setting out on a world tour. He travelled overland to Los Angeles and crossed the Pacific to Honolulu, to Samoa, Fiji, New Zealand and Australia. During the journey he visited hospitals and delivered lectures. His journal of the trip is held b
Edinburgh University's Heritage Collections
In 1938 he was elected a member of the
Aesculapian Club The Aesculapian Club of Edinburgh is one of the oldest medical dining clubs in the world. It was founded in April 1773 by Dr. Andrew Duncan. Membership of the club is limited to 11 Fellows of the Royal College of Physicians of Edinburgh and ...
. He chaired the Advisory Committee on Blood Transfusion which set up blood banks in Scotland in 1939. Fraser's surgical career encompassed paediatric, abdominal, cardiothoracic and breast surgery and he wrote extensively on all of these. At a time when surgery on the heart was unthinkable, Fraser kept his interest in its possibility. On 19 October 1940 he became the first surgeon in the British Isles to successfully ligate an uninfected patent ductus arteriosus, two weeks after Oswald Tubbs had successfully ligated an infected ductus in London. Robert Gross had performed the first in Boston in 1938. Before retiring from surgery Fraser operated on 12 such cases. In addition, he had performed left cervical
sympathectomy A sympathectomy is an irreversible procedure during which at least one sympathetic ganglion is removed. One example is the lumbar sympathectomy, which is advised for occlusive arterial disease in which L2 and L3 ganglia along with intervening sy ...
for
angina Angina, also known as angina pectoris, is chest pain or pressure, usually caused by insufficient blood flow to the heart muscle (myocardium). It is most commonly a symptom of coronary artery disease. Angina is typically the result of parti ...
. His experience with O'Shaughnessy's cardio-omentopexy surgery was less successful. In October 1944 he was appointed principal of the University of Edinburgh. He was regarded as a major contributor of the golden age for Edinburgh surgery.


Death and legacy

The workload strain of the
Second World War World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
contributed to his deteriorating health, and following his guided smooth transition of the university from war time to peacetime, Sir John Fraser died in Edinburgh on 1 December 1947.


Honours

The
Freedom Freedom is the power or right to speak, act, and change as one wants without hindrance or restraint. Freedom is often associated with liberty and autonomy in the sense of "giving oneself one's own laws". In one definition, something is "free" i ...
of Tain was conferred upon Fraser in 1925. He was awarded an Honorary Fellowship by the American College of Surgeons in 1926. He was Surgeon to the King in Scotland, and was created a Knight Commander of the Victorian Order (KCVO) in 1937. In the
1943 Birthday Honours The King's Birthday Honours 1943 were appointments by King George VI to various orders and honours to reward and highlight good works by people of the British Empire. They were published on 2 June 1943 for the United Kingdom and Canada. The re ...
he was made a Baronet with the creation of the Fraser Baronetcy, of Tain in the County of Ross. He was awarded the honorary degree of LL.D. by the University of Edinburgh in 1944.


Selected publications

*
Tuberculosis of the bones and joints in children
'. London: A & C Black, 1914. *
Surgery at a Casualty Clearing Station
' (with Cuthbert Wallace). London: A & C Black, 1918. * ''Surgery of Childhood''. London: Arnold & Co, 1926.


References

{{DEFAULTSORT:Fraser, John 1885 births 1947 deaths People from Tain Nobility from Highland (council area) Military personnel from Ross and Cromarty Principals of the University of Edinburgh Academics of the University of Edinburgh Scottish surgeons 20th-century Scottish medical doctors Recipients of the Military Cross Fellows of the Royal College of Surgeons of Edinburgh People educated at Tain Royal Academy Royal Army Medical Corps officers British Army personnel of World War I Members of the Royal Victorian Order Scottish medical writers Baronets in the Baronetage of the United Kingdom Alumni of the University of Edinburgh Medical School 20th-century British surgeons 20th-century Scottish military personnel Members of the Harveian Society of Edinburgh