Jens Meiler
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Jens Meiler (born August 31, 1974) is a
German-American German Americans (, ) are Americans who have full or partial German ancestry. According to the United States Census Bureau's figures from 2022, German Americans make up roughly 41 million people in the US, which is approximately 12% of the pop ...
biologist A biologist is a scientist who conducts research in biology. Biologists are interested in studying life on Earth, whether it is an individual Cell (biology), cell, a multicellular organism, or a Community (ecology), community of Biological inter ...
and structural chemist. He currently serves as a Professor of
Chemistry Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
and Associate Professor of
Pharmacology Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur betwee ...
and
Biomedical Informatics Health informatics combines communications, information technology (IT), and health care to enhance patient care and is at the forefront of the medical technological revolution. It can be viewed as a branch of engineering and applied science. ...
at
Vanderbilt University Vanderbilt University (informally Vandy or VU) is a private university, private research university in Nashville, Tennessee, United States. Founded in 1873, it was named in honor of shipping and railroad magnate Cornelius Vanderbilt, who provide ...
. His research focuses on
protein structure Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers specifically polypeptides formed from sequences of amino acids, which are the monomers of the polymer. A single amino acid ...
s and
computational biology Computational biology refers to the use of techniques in computer science, data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer sci ...
, drawing on interdisciplinary techniques from other sciences.


Biography

Meiler was born in
Leipzig Leipzig (, ; ; Upper Saxon: ; ) is the most populous city in the States of Germany, German state of Saxony. The city has a population of 628,718 inhabitants as of 2023. It is the List of cities in Germany by population, eighth-largest city in Ge ...
, East Germany. He attended the
University of Leipzig Leipzig University (), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 December 1409 by Frederick I, Electo ...
, where he received a B.S. in
biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...
in 1995. He then continued onto the University of Frankfurt receiving a
Ph.D. A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...
in
structural biology Structural biology deals with structural analysis of living material (formed, composed of, and/or maintained and refined by living cells) at every level of organization. Early structural biologists throughout the 19th and early 20th centuries we ...
in 2001, where he was funded by the German National Merit Foundation scholarship. His doctoral adviser was Christian Griesinger, Director of the Max Planck Institute for Biophysical Chemistry. Meiler then completed his
post-doctoral A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary academ ...
work in the same field through the
Human Frontier Science Program } The International Human Frontier Science Program Organization (HFSPO) is a non-profit organization, based in Strasbourg, France, that funds basic research in life sciences. The organization implements the Human Frontier Science Program (HFSP) and ...
at the
University of Washington The University of Washington (UW and informally U-Dub or U Dub) is a public research university in Seattle, Washington, United States. Founded in 1861, the University of Washington is one of the oldest universities on the West Coast of the Uni ...
from 2001 to 2004. His postdoctoral adviser was
David Baker (biochemist) David Baker (born October 6, 1962) is an American biochemist and computational biology, computational biologist who has pioneered methods to Protein design, design proteins and protein structure prediction, predict their three-dimensional struct ...
, the Henrietta and Aubrey Davis Endowed Professor in Biochemistry,
University of Washington The University of Washington (UW and informally U-Dub or U Dub) is a public research university in Seattle, Washington, United States. Founded in 1861, the University of Washington is one of the oldest universities on the West Coast of the Uni ...
. After completing a postdoctoral fellowship, Meiler served as an Assistant Professor of Chemistry, Pharmacology, and Biomedical Informatics at
Vanderbilt University Vanderbilt University (informally Vandy or VU) is a private university, private research university in Nashville, Tennessee, United States. Founded in 1873, it was named in honor of shipping and railroad magnate Cornelius Vanderbilt, who provide ...
. In 2011, he received
tenure Tenure is a type of academic appointment that protects its holder from being fired or laid off except for cause, or under extraordinary circumstances such as financial exigency or program discontinuation. Academic tenure originated in the United ...
and was promoted to Associate Professor. During this time, he received the Vanderbilt Institute for Chemical Biology Prize for Highly Cited Article award (2014). In 2019, Meiler was awarded the
Alexander von Humboldt Professorship The Alexander von Humboldt Professorship is an academic prize named after Alexander von Humboldt and awarded by the Alexander von Humboldt Foundation since 2008. The prize is intended to attract internationally leading scientists from abroad to Ger ...
from the
Alexander von Humboldt Foundation The Alexander von Humboldt Foundation () is a foundation that promotes international academic cooperation between scientists and scholars from Germany and abroad. Established by the government of the Federal Republic of Germany, it is funded by t ...
his research in bioinformatics and protein structures. As part of the award, Meiler collaborated with colleagues at
Leipzig University Leipzig University (), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 December 1409 by Frederick I, Electo ...
on the study of
G-protein coupled receptors G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily related ...
. He was also named the Stevenson Chair in Chemistry. At Vanderbilt, his lab conducts research on
cheminformatics Cheminformatics (also known as chemoinformatics) refers to the use of physical chemistry theory with computer and information science techniques—so called "'' in silico''" techniques—in application to a range of descriptive and prescriptive ...
, Ligand docking, and
protein design Protein design is the rational design of new protein molecules to design novel activity, behavior, or purpose, and to advance basic understanding of protein function. Proteins can be designed from scratch (''de novo'' design) or by making calcul ...
. It is funded by a number of national organizations, including the
National Science Foundation The U.S. National Science Foundation (NSF) is an Independent agencies of the United States government#Examples of independent agencies, independent agency of the Federal government of the United States, United States federal government that su ...
and the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
. The Meiler Lab at
Vanderbilt University Vanderbilt University (informally Vandy or VU) is a private university, private research university in Nashville, Tennessee, United States. Founded in 1873, it was named in honor of shipping and railroad magnate Cornelius Vanderbilt, who provide ...
specializes in
computational A computation is any type of arithmetic or non-arithmetic calculation that is well-defined. Common examples of computation are mathematical equation solving and the execution of computer algorithms. Mechanical or electronic devices (or, historic ...
,
structural A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ...
, and
chemical biology Chemical biology is a scientific discipline between the fields of chemistry and biology. The discipline involves the application of chemical techniques, analysis, and often small molecules produced through synthetic chemistry, to the study and m ...
. Their focus is on protein-protein interactions,
protein design Protein design is the rational design of new protein molecules to design novel activity, behavior, or purpose, and to advance basic understanding of protein function. Proteins can be designed from scratch (''de novo'' design) or by making calcul ...
, ligand docking, and
cheminformatics Cheminformatics (also known as chemoinformatics) refers to the use of physical chemistry theory with computer and information science techniques—so called "'' in silico''" techniques—in application to a range of descriptive and prescriptive ...
. Their findings on small-molecule therapeutics and receptor-binding proteins have been published in
academic journals An academic journal (or scholarly journal or scientific journal) is a periodical publication in which scholarship relating to a particular academic discipline is published. They serve as permanent and transparent forums for the dissemination, scr ...
like ''
Nature Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...
''. In recent years, Meiler has also conducted research on
artificial intelligence Artificial intelligence (AI) is the capability of computer, computational systems to perform tasks typically associated with human intelligence, such as learning, reasoning, problem-solving, perception, and decision-making. It is a field of re ...
. His work has been featured in newspapers in both the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
and
Germany Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total popu ...
.


Honors and awards

* 2019
Alexander von Humboldt Professorship The Alexander von Humboldt Professorship is an academic prize named after Alexander von Humboldt and awarded by the Alexander von Humboldt Foundation since 2008. The prize is intended to attract internationally leading scientists from abroad to Ger ...
from the
Alexander von Humboldt Foundation The Alexander von Humboldt Foundation () is a foundation that promotes international academic cooperation between scientists and scholars from Germany and abroad. Established by the government of the Federal Republic of Germany, it is funded by t ...
* 2015 Vanderbilt University Chancellor Faculty Fellow * 2014 Vanderbilt Institute for Chemical Biology Prize for Highly Cited Article * 2002–2005 Human Frontier Science Program postdoctoral fellowship * 1998–2001 Kekulé Scholarship, German Chemical Industry Association * 1994–1998 German National Merit Foundation scholarship


Personal life

Jens Meiler lives in
Nashville, Tennessee Nashville, often known as Music City, is the capital and List of municipalities in Tennessee, most populous city in the U.S. state of Tennessee. It is the county seat, seat of Davidson County, Tennessee, Davidson County in Middle Tennessee, locat ...
and
Leipzig, Germany Leipzig (, ; ; Upper Saxon: ; ) is the most populous city in the States of Germany, German state of Saxony. The city has a population of 628,718 inhabitants as of 2023. It is the List of cities in Germany by population, eighth-largest city in Ge ...
.


Notable publications

* * * *


References


External links

* {{DEFAULTSORT:Meiler, Jens 1974 births Living people 21st-century American chemists 21st-century German chemists Structural biologists