''Iltovirus'' is a genus of
viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almo ...
in the order ''
Herpesvirales
''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans cause ...
'', in the family ''
Herpesviridae
''Orthoherpesviridae'', previously named and more widely known as ''Herpesviridae'', is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are commonly known as herp ...
'', in the subfamily ''
Alphaherpesvirinae
''Alphaherpesvirinae'' is a subfamily of viruses in the family ''Herpesviridae'', primarily distinguished by reproducing more quickly than other subfamilies in the ''Herpesviridae''. In animal virology the most important herpesviruses belong to ...
''. Birds,
galliform birds,
psittacine birds,
chicken
The chicken (''Gallus gallus domesticus'') is a domesticated subspecies of the red junglefowl (''Gallus gallus''), originally native to Southeast Asia. It was first domesticated around 8,000 years ago and is now one of the most common and w ...
s,
turkeys, and
quail
Quail is a collective name for several genera of mid-sized birds generally placed in the order Galliformes. The collective noun for a group of quail is a flock, covey, or bevy.
Old World quail are placed in the family Phasianidae, and New ...
serve as natural hosts. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious
laryngotracheitis; psHV-1:
Pacheco's disease.
Species
The genus consists of the following species:
* ''
Iltovirus cacatuidalpha2''
* ''
Iltovirus gallidalpha1'', also called
Gallid alphaherpesvirus 1
* ''
Iltovirus psittacidalpha1'', also called
Psittacid alphaherpesvirus 1
* ''
Iltovirus psittacidalpha5''
Structure
Viruses in ''Iltovirus'' are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 120-200 nm. Genomes are linear and non-segmented, around 150kb in length.
Life cycle
Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral gB, gC, gD and gH proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as the natural host. Transmission routes are contact, contamination, and air borne particles.
References
External links
Viralzone: ''Iltovirus''ICTV
{{Taxonbar, from=Q12021507
Virus genera
Alphaherpesvirinae