IBM 2997
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IBM International Business Machines Corporation (using the trademark IBM), nicknamed Big Blue, is an American Multinational corporation, multinational technology company headquartered in Armonk, New York, and present in over 175 countries. It is ...
's development of the IBM 2997 Blood cell Separator lay in the personal
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of one of IBM's development
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, George Judson. In 1962, Judson's son, Tom, was diagnosed with leukemia. His physician was able to have Tom admitted to the Clinical Center of the National Cancer Institute (NCI) at the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
(NIH). On admission, they showed Judson a procedure to remove white blood cells from a patient. It was laborious. They would remove two units (450 ml) of blood, spin them in a bucket centrifuge, express the plasma into a satellite bag, and the white cells into another satellite bag. The packed red cells and the plasma would be recombined and administered to the patient. This would be repeated over and over. Judson, being an engineer, suggested that this could be done on a continuous-flow basis. He was sent to see Dr. Emil J. Freireich who expressed enthusiasm for the project. Judson returned to IBM and asked for a year's leave of absence to work on his ideas. IBM gave him the one-year leave with pay and provided engineering assistance. Judson's work led to the development of the NCI Blood Cell Separator and later to the IBM 2990 Blood Cell Separator which could harvest white blood cells from blood donors, to support leukemia patients to keep them alive. The subsequent development of the machine as the IBM 2997, essentially a continuous centrifuge which separated the blood into red blood cells, white blood cells, and blood plasma (used in plasmapheresis), was picked up by IBM's Systems Supplies Division (SSD) which was already ready
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the IBM 2991 Blood cell Processor. The (disposable) supplies element represented a large part of the revenue stream.J Clin Apher. 1985;2(3):258-61.Platelet collection using the IBM 2997 cell separator.Bond R, Wood L, Jacobs P, Kernoff LM.


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