Hydroxynefazodone is a phenylpiperazine compound and a major

metabolite In biochemistry, a metabolite is an intermediate or end product of metabolism. The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, ...

of the

antidepressant Antidepressants are a class of medication used to treat major depressive disorder, anxiety disorders, chronic pain conditions, and to help manage addictions. Common side-effects of antidepressants include dry mouth, weight gain, dizziness ...

nefazodone Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant which was first marketed by Bristol-Myers Squibb (BMS) in 1994 but has since largely been discontinued. BMS withdrew it fro ...

. It has similar

biological activity In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter. When a drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or ...

and a similar

elimination half-life Biological half-life (also known as elimination half-life, pharmacologic half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration ( Cmax) to half of Cmax in the bl ...

(1.5 to 4 hours) to those of nefazodone, and may contribute significantly to its effects.

References

5-HT1A agonists 5-HT2A antagonists Alpha-1 blockers Antidepressants Anxiolytics H1 receptor antagonists Human drug metabolites meta-Chlorophenylpiperazines Secondary alcohols Serotonin–norepinephrine reuptake inhibitors Triazoles {{Nervous-system-drug-stub

See also

References