Heat Rash
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Miliaria, commonly known as heat rash, sweat rash, or prickly heat, is a
skin disease A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, Nail (anatomy), nails, and related muscle and glands. The major funct ...
marked by small, itchy
rash A rash is a change of the skin that affects its color, appearance, or texture. A rash may be localized in one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, chapped, dry, cracke ...
es due to sweat trapped under the skin by clogged sweat-gland ducts. Similar to
sunburn Sunburn is a form of radiation burn that affects living tissue, such as skin, that results from an overexposure to ultraviolet (UV) radiation, usually from the Sun. Common symptoms in humans and other animals include red or reddish skin tha ...
, miliaria is common in hot and humid conditions, such as in the
tropics The tropics are the regions of Earth surrounding the equator, where the sun may shine directly overhead. This contrasts with the temperate or polar regions of Earth, where the Sun can never be directly overhead. This is because of Earth's ax ...
and during the summer. Although it affects people of all ages, it is especially common in children and infants due to their underdeveloped sweat glands.


Signs and symptoms

Symptoms of miliaria include small, red rashes, called
papules A papule is a small, well-defined bump in the skin. It may have a rounded, pointed or flat top, and may have a dip. It can appear with a stalk, be thread-like or look warty. It can be soft or firm and its surface may be rough or smooth. Some ...
, which are irritated and itchy. These may simultaneously occur at a number of areas on a patient's body, the most common including the upper chest, neck, elbow creases, under the breasts, and under the scrotum. Other areas include
skin fold Skin folds or skinfolds are areas of skin that are naturally folded. Many skin folds are distinct, heritable anatomical features, and may be used for identification of animal species, while others are non-specific and may be produced either by in ...
s and areas of the body that may rub against clothing, such as the back, chest, and stomach. A related and sometimes simultaneous condition is
folliculitis Folliculitis is the infection and inflammation of one or more hair follicles. The condition may occur anywhere on hair-covered skin. The rash may appear as pimples that come to white tips on the face, chest, back, arms, legs, buttocks, or head. A ...
, where
hair follicles The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between ho ...
become plugged with foreign matter, resulting in inflammation. The symptoms relating to miliaria should not be confused with
shingles Shingles, also known as herpes zoster or zona, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. T ...
, as they can be very similar. Shingles is limited to one side of the body, but also has a rash-like appearance. It is also accompanied by a prickly sensation and pain throughout the region. Those who suspect they have shingles and not miliaria should seek medical advice immediately as the sooner antivirals are taken, the better.


Types

Miliaria can be classified according to the top level at which obstruction occurs in the sweat glands.


Miliaria crystallina

The most superficial obstruction (with the most mild clinical presentation), is known as miliaria crystallina; instead of a rash, the patient presents with multiple, tiny, blister-like lesions that look like beads of perspiration and essentially cause no symptoms. Miliaria crystallina is also known as sudamina or miliaria crystalline. The superficial
vesicle Vesicle may refer to: ; In cellular biology or chemistry * Vesicle (biology and chemistry), a supramolecular assembly of lipid molecules, like a cell membrane * Synaptic vesicle ; In human embryology * Vesicle (embryology), bulge-like features ...
s are not associated with an inflammatory reaction.


Miliaria rubra

The most commonly encountered form of the illness is miliaria rubra, in which obstruction causes leakage of sweat into the deeper layers of the epidermis, provoking a local inflammatory reaction and giving rise to the typical appearance of redness (hence rubra) and larger (but still only a few millimetres), blister-like lesions. This form of the illness is often accompanied by the typical symptoms—intense itching or "pins and needles" with a lack of sweating (
anhidrosis Hypohidrosis is a medical condition in which a person exhibits diminished sweating in response to appropriate stimuli. In contrast with hyperhidrosis, which is a socially troubling yet often benign condition, the consequences of untreated hypohidr ...
) to affected areas. A small risk of
heat exhaustion Heat exhaustion is a heat-related illness characterized by the body's inability to effectively cool itself, typically occurring in high ambient temperatures or during intense physical exertion. In heat exhaustion, core body temperature ranges from ...
exists due to inability to sweat if the rash affects a large proportion of the body's surface area or the patient continues to engage in heat-producing activity. Miliaria rubra is also known as prickly heat and heat rash. Differential diagnosis should be used to rule out
polycythemia vera In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. Approximately 98% of PV patients have a JAK2 gene mutation in their blood-forming cells (compared with 0.1-0 ...
, which is a rare hematological disorder and appears more often in males than females, generally not before the age of 40. Both disorders share a common trait of appearing after taking a hot shower.


Miliaria profunda

The most severe form of miliaria, miliaria profunda, sometimes referred to as "wildfire" due to the rapid spread and severe burning sensations, generally occurs as a complication of repeated episodes of miliaria rubra. The obstruction is deep in the structure of the sweat gland, causing the gland's secretions to leak between the superficial and deep layers of the skin. The rash and associated symptoms tend to appear within hours of an activity provoking sweating, but similarly fade within hours when the stimulus for the sweating is removed. Miliaria profunda is characterised by non
pruritic An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both a ...
, flesh-coloured, deep-seated, whitish
papule A papule is a small, well-defined bump in the skin lesion, skin. It may have a rounded, pointed or flat top, and may have a umbilication, dip. It can appear with a Peduncle (anatomy), stalk, be thread-like or look warty. It can be soft or firm a ...
s. The rash tends to be flesh-coloured as opposed to the prominent redness of miliaria rubra, and the risk of heat exhaustion is larger. Miliaria profunda is also less commonly known as "mammillaria"


Miliaria pustulosa

Miliaria pustulosa describes pustules due to inflammation and bacterial infection. Miliaria pustulosa is preceded by another
dermatitis Dermatitis is a term used for different types of skin inflammation, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened ...
that has produced injury, destruction, or blocking of the sweat ducts.


Postmiliarial hypohidrosis

Postmiliarial hypohidrosis is a skin condition that results from occlusion of sweat ducts and pores, and may be severe enough to impair an individual's ability to perform sustained work in a hot environment.


Tropical anhidrotic asthenia

Tropical anhidrotic asthenia is a skin condition, a rare form of miliaria, with long-lasting poral occlusion, which produces anhidrosis and heat retention.


Occlusion miliaria

Occlusion miliaria is a skin condition that is accompanied by anhidrosis and increased heat-stress susceptibility, all after the application of extensive polyethylene film occlusion for 48 hours or longer.


Colloid milium

Colloid milium is a skin condition characterized by a translucent, flesh-colored, or slightly yellow, 1 to 5 mm
papule A papule is a small, well-defined bump in the skin lesion, skin. It may have a rounded, pointed or flat top, and may have a umbilication, dip. It can appear with a Peduncle (anatomy), stalk, be thread-like or look warty. It can be soft or firm a ...
s.


Pathophysiology

Miliaria occurs when sweat glands become clogged due to dead skin cells or bacteria such as ''
Staphylococcus epidermidis ''Staphylococcus epidermidis'' is a Gram-positive bacterium, and one of over 40 species belonging to the genus ''Staphylococcus''. It is part of the human flora, normal human microbiota, typically the skin flora, skin microbiota, and less commonl ...
'', a common bacterium that occurs on the skin, which is also associated with
acne Acne ( ), also known as ''acne vulgaris'', is a long-term Cutaneous condition, skin condition that occurs when Keratinocyte, dead skin cells and Sebum, oil from the skin clog hair follicles. Typical features of the condition include comedo, ...
. The trapped sweat leads to irritation (prickling), itching, and a rash of very small blisters, usually in a localized area of the skin.


Prevention

Prickly heat can be prevented by avoiding activities that induce sweating, using air conditioning to cool the environment, wearing light clothing, and in general, avoiding hot and humid weather. Frequent cool showers or cool baths with mild soap can help to prevent heat rash.


Treatment

The primary remedy for prickly heat or rash is to wear lighter clothing, or otherwise avoid overheating one's body. The immediate treatment of the involved skin areas involves the use of a soothing ointment, such as calamine lotion. Medical assistance should be sought for the first episode of a rash with the appearance of miliaria. The
differential diagnosis In healthcare, a differential diagnosis (DDx) is a method of analysis that distinguishes a particular disease or condition from others that present with similar clinical features. Differential diagnostic procedures are used by clinicians to di ...
includes several conditions that an experienced practitioner should be able to recognise and may require treatment distinct from the usual measures taken for miliaria. In most cases, the rash of miliaria resolves without intervention, but severe cases can last for weeks and cause significant disability. General measures should be recommended for all patients, including moving to an air-conditioned environment if possible, avoiding sweat-provoking activities and occlusive clothing, and taking frequent, cool showers. The use of topical antibacterials (including antibacterial soaps) may shorten the duration of symptoms in miliaria rubra even in the absence of obvious superinfection. Other topical agents that may reduce the severity of symptoms include anti-itch preparations such as
calamine Calamine, also known as calamine lotion, is a medication made from powdered calamine (mineral), calamine mineral that is used to treat mild itchiness. Conditions treated include sunburn, insect bites, Toxicodendron radicans, poison ivy, poiso ...
or
menthol Menthol is an organic compound, specifically a Monoterpene, monoterpenoid, that occurs naturally in the oils of several plants in the Mentha, mint family, such as Mentha arvensis, corn mint and peppermint. It is a white or clear waxy crystallin ...
- or
camphor Camphor () is a waxy, colorless solid with a strong aroma. It is classified as a terpenoid and a cyclic ketone. It is found in the wood of the camphor laurel (''Cinnamomum camphora''), a large evergreen tree found in East Asia; and in the kapu ...
-based preparations, and topical steroid creams. Caution should be used, however, with oil-based preparations (ointments and oily creams as opposed to water-based or aqueous lotions) that may increase blockage of the sweat glands and prolong the duration of illness. Other agents have been investigated including supplemental vitamin A and C and vitamin A based medications, but little scientific evidence supports any of the above treatments in reducing the duration of symptoms or frequency of complications. In most tropical areas, the local dispensaries sell prickly heat powder, a talc admixture containing drying milk proteins (labilin) and
Triclosan Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of act ...
to fight bacterial infection. These include cooling menthol to help alleviate difficulty getting to sleep. This is an effective treatment; the powder stays on the skin longer and treats bacteria dispersed into bed linens, providing a reasonably dry refuge area for healing. Miliaria often covers large areas, and generous use of cortisone may be contraindicated for reasons stated on package warnings. Regular talcum powder does not reduce the rash, but can alleviate burning and itching. In cases where the rash has developed into open blisters or pustular lesions, a doctor should be consulted since more aggressive, medically monitored treatment may be required.


See also

*
Cholinergic urticaria Cholinergic urticaria (CholU, CU) is a form of hives (urticaria) that is triggered by an elevation in body temperature, breaking a sweat, or exposure to heat. It is also sometimes called exercise-induced urticaria or heat hives. The condition is ...
*
Sweat allergy Perspiration, also known as sweat, is the fluid secreted by sweat glands in the skin of mammals. Two types of sweat glands can be found in humans: eccrine glands and apocrine glands. The eccrine sweat glands are distributed over much of the ...


References


External links

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- with pictures
WebMd Description


{{Disorders of skin appendages Apocrine Skin conditions resulting from physical factors