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Efocipegtrutide (HM15211) is a triple agonist of the
glucagon Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises the concentration of glucose and fatty acids in the bloodstream and is considered to be the main catabolic hormone of the body. It is also used as a Glucagon (medic ...
, GIP, and
glucagon-like peptide 1 receptor The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It is involved in the control of blood sugar level by enhancing insulin secretion. In humans it i ...
s. It is being studied for obesity and nonalcoholic steatohepatitis.


References

GLP-1 receptor agonists Glucagon receptor agonists GIP receptor agonists Peptide therapeutics {{pharma-stub