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HHCP-O-acetate (HHCPO, HHCP-O) is a semi-synthetic derivative of
tetrahydrocannabiphorol Tetrahydrocannabiphorol (THCP) is a potent phytocannabinoid, a Cannabinoid receptor type 1, CB1 and Cannabinoid receptor type 2, CB2 agonist, receptor agonist which was known as a synthetic homologue of tetrahydrocannabinol (THC), but for the ...
(THCP) derived in several steps by
hydrogenation Hydrogenation is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum. The process is commonly employed to redox, reduce or Saturated ...
to
hexahydrocannabiphorol Hexahydrocannabiphorol (HHCP, sometimes mistakenly referred to as ''hexahydroxycannabiphorol'') is a semi-synthetic cannabinoid derivative which has been marketed since around 2021. It is believed to be made from the hydrogenation of tetrahydro ...
(HHCP) followed by
acetylation : In chemistry, acetylation is an organic esterification reaction with acetic acid. It introduces an acetyl group into a chemical compound. Such compounds are termed ''acetate esters'' or simply ''acetates''. Deacetylation is the opposite react ...
of the OH group. It has been found as a component of grey-market cannabis products such as e-cigarette liquids and edible gumdrops, and is allegedly a potent and long-lasting psychoactive cannabinoid.


Confusion about acronym

Some vendors have mistakenly claimed that HHCPO stands for hexahydrocannabinol propionate (HHC-P) or hexahydrocannabinol cyclopropyl ether, but these are different compounds. :


See also

*
Abeo-HHC acetate Abeo-HHC acetate is a semi-synthetic derivative of tetrahydrocannabinol, first described in the 1980s. It is synthesised from delta-11-tetrahydrocannabinol, which can be made to undergo a ring expansion reaction via a hydrazone intermediate. It ...
*
Hexahydrocannabinol Hexahydrocannabinol (HHC) is a phytocannabinoid that has been reported as a trace component of ''Cannabis sativa''. It can also be synthesized by hydrogenation of tetrahydrocannabinol (THC). The synthesis and bioactivity of HHC was first reporte ...
*
Hexahydrocannabihexol Hexahydrocannabihexol (HHCH) is a semi-synthetic cannabinoid derivative. It was first synthesised by Roger Adams in 1942 and found to be more potent than either the pentyl or heptyl homologues, or the unsaturated tetrahydrocannabinol analogue. H ...
*
THC-O-acetate THC-O-acetate (THC acetate ester, O-acetyl-THC, THC-O, AcO-THC) is the acetate ester of THC. The term ''THC-O-acetate'' and its variations are commonly used for two types of the substance, dependent on which cannabinoid it is synthesized from. ...
*
THCP-O-acetate THCP-O-acetate (THCP-O) is a semi-synthetic derivative of tetrahydrocannabiphorol (THCP) derived by acetylation of the OH group. It has been found as a component of grey-market cannabis products such as e-cigarette liquids and edible gummy lolli ...


References

Cannabinoids Acetate esters Heterocyclic compounds with 3 rings Benzopyrans {{cannabinoid-stub