The HEL cell line is an
immortalised cell line
An immortalised cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cel ...
from a 30-year old male
Acute erythroid leukemia
Acute erythrocyte leukemia is a rare form of acute myeloid leukemia (less than 5% of AML cases) where the myeloproliferation is of erythrocytic precursors. It is defined as type "M6" under the FAB classification.
Signs and symptoms
The most com ...
patient,
used in
biomedical research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from " basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scienti ...
.
HEL cell is capable of induced
globin
The globins are a superfamily of heme-containing globular proteins, involved in binding and/or transporting oxygen. These proteins all incorporate the globin fold, a series of eight alpha helical segments. Two prominent members include myog ...
synthesis, producing mainly
Gγ and
Aγ chains.
[
]
See also
Other cell lines in LL-100 panel The LL-100 panel is a group of 100 human leukemia and lymphoma cell line, can be used in model of biomedical research.
Purpose
LL-100 panel cell lines cover the full spectrum of human leukemia and lymphoma including T-cell, B-cell and myeloid ...
References
{{Reflist
External links
Cellosaurus entry for HEL
Human cell lines