LL-100 Panel
The LL-100 panel is a group of 100 human leukemia and lymphoma cell line, can be used in model of biomedical research. Purpose LL-100 panel cell lines cover the full spectrum of human leukemia and lymphoma including T-cell, B-cell and myeloid malignancies. List of LL-100 Cell Lines Pre-B-ALL B-NHL: Burkitt/B-ALL B-NHL: CLL/PLL B-NHL: DLBCL ABC B-NHL: DLBCL GC B-NHL: HCL B-NHL: MCL B-NHL: PEL B-NHL: PMBL Multiple Myeloma/PCL Hodgkin Lymphoma T-ALL/T-LL Mature T-Malignancy NK Malignancy ALCL AML myelocytic AML monocytic AML erythroid AML megakaryocytic CML myeloid BC CML lymphoid BC MPN See also * NCI-60, 60 human cancer cell lines used by the NCI * List of breast cancer cell lines Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture Cell culture or tissue culture is the process by which cells ar ...
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Leukemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chron ...
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Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). Early on, there are typically no symptoms. Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur. Enlargement of the spleen and low red blood cells (anemia) may also occur. It typically worsens gradually over years. Risk factors include having a family history of the disease, with 10% of those who develop CLL having a family history of the disease. Exposure to Agent Orange, certain insecticides, sun exposure, exposure to hepatitis C virus, and common infections are also considered risk factors. CLL results in the buildup of B cell lymphocytes in the bone marrow, lymph nodes, and blood. These cells do not function well and crowd out healthy blood cells. CLL is divided into two main types: those with a mutated IGHV gene and those without. Diagnosis is typically based on ...
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RI-1 (cell Line)
RI-1 may refer to: * Rhode Island's 1st congressional district * RI-1 (chemical), an experimental oncology drug * U.S. Route 1 in Rhode Island U.S. Route 1 (US 1) in Rhode Island Rhode Island (, like ''road'') is a U.S. state, state in the New England region of the Northeastern United States. It is the List of U.S. states by area, smallest U.S. state by area and the List of s ...