The LL-100 panel is a group of 100 human
leukemia and
lymphoma cell line
An immortalised cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cell ...
,
can be used in model of
biomedical research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientif ...
.
Purpose
LL-100 panel cell lines cover the full spectrum of human leukemia and lymphoma including
T-cell,
B-cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted o ...
and
myeloid
Myeloid tissue, in the bone marrow sense of the word '' myeloid'' ('' myelo-'' + ''-oid''), is tissue of bone marrow, of bone marrow cell lineage, or resembling bone marrow, and myelogenous tissue (''myelo-'' + '' -genous'') is any tissue of, ...
malignancies.
[
]
List of LL-100 Cell Lines
Pre-B-ALL
B-NHL: Burkitt/B-ALL
B-NHL: CLL/PLL
B-NHL: DLBCL ABC
B-NHL: DLBCL GC
B-NHL: HCL
B-NHL: MCL
B-NHL: PEL
B-NHL: PMBL
Multiple Myeloma
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, an ...
/PCL
Hodgkin Lymphoma
T-ALL/T-LL
Mature T-Malignancy
NK Malignancy
ALCL
AML myelocytic
AML monocytic
AML erythroid
AML megakaryocytic
CML myeloid BC
CML lymphoid BC
MPN MPN may refer to:
* Manufacturer part number, an identifier
* Memory part number, an identifier for computer memory
* Master promissory note, a wide-encompassing accounting contract
* Metal-phenolic network, a supramolecular coordination structur ...
See also
* NCI-60, 60 human cancer cell lines used by the NCI
* List of breast cancer cell lines
Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture
Cell culture or tissue culture is the process by which cells are ...
References
{{reflist
*
Leukemia