Gray zone lymphoma, often presenting as large
tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
s in the
mediastinum
The mediastinum (from ;: mediastina) is the central compartment of the thoracic cavity. Surrounded by loose connective tissue, it is a region that contains vital organs and structures within the thorax, mainly the heart and its vessels, the eso ...
, is a type of
lymphoma
Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). The name typically refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enlarged lymph node ...
that is characterized by having cellular features of both classic
Hodgkin's lymphoma
Hodgkin lymphoma (HL) is a type of lymphoma in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the lymph nodes. The condition was named a ...
s (cHL) and
large B-cell lymphomas.
Sources
* Traverse-Glehen A, Mediastinal gray zone lymphoma: the missing link between classic Hodgkin's lymphoma and mediastinal large
B-cell lymphoma. Am J Surg Pathol 2005 Nov; 29(11):1411–21
Hodgkin’s lymphoma and Grey-zone lymphomas
Lymphoma
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