The Fusobacteriales-1 RNA motif is a conserved
RNA
Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA). RNA and deoxyrib ...
structure that was
discovered by bioinformatics.
Fusobacteriales-1 motif RNAs are found in
Fusobacteriales.
Most Fusobacteriales-1 RNAs are located upstream of
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
s homologous to the locus FSAG_00736, which encodes a hypothetical protein in ''Fusobacterium peridonticum''.
However, some Fusobacteriales-1 RNAs are located upstream of genes that do not appear to be homologous to FSAG_00736.
Additionally 1 Fusobacteriales-1 RNAs is not found upstream of a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
-coding gene.
In view of this information, it is ambiguous whether Fusobacteriales-1 RNAs function as
cis-regulatory element
''Cis''-regulatory elements (CREs) or ''cis''-regulatory modules (CRMs) are regions of non-coding DNA which regulate the transcription of neighboring genes. CREs are vital components of genetic regulatory networks, which in turn control morpho ...
s or whether they operate in ''trans''.
References
{{reflist
Non-coding RNA