Firsocostat is an

acetyl-CoA carboxylase Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme () that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC ...

inhibitor that functions in the liver. Its original designation was GS-0976. It was discovered by Nimbus Therapeutics. The drug is under development by

Gilead Gilead or Gilad (, ; ''Gilʿāḏ'', , ''Jalʻād'') is the ancient, historic, biblical name of the mountainous northern part of the region of Transjordan.''Easton's Bible Dictionary'Galeed''/ref> The region is bounded in the west by the J ...

as a treatment for

non-alcoholic fatty liver disease An alcohol-free or non-alcoholic drink, also known as a temperance drink, is a version of an alcoholic drink made without alcohol, or with the alcohol removed or reduced to almost zero. These may take the form of a non-alcoholic mixed drink or n ...

References

{{Reflist 2-Methoxyphenyl compounds Carboxylic acids Oxazoles