Fabrice André
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Fabrice André is a French medical oncologist specializing in
breast cancer Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...
. He is the Director of Research at Gustave Roussy in
Villejuif Villejuif () is a commune in the southern suburbs of Paris, France. It is located from the centre of Paris. Name The earliest reference to Villejuif appears in a bill signed by the Pope Callixtus II on 27 November 1119. It refers to Villa J ...
,
France France, officially the French Republic, is a country located primarily in Western Europe. Overseas France, Its overseas regions and territories include French Guiana in South America, Saint Pierre and Miquelon in the Atlantic Ocean#North Atlan ...
, and a Professor of Medicine at the
University of Paris-Saclay Paris-Saclay University (, ) is a combined Research institute, technological research institute and Public university, public research university in Orsay, France. Paris-Saclay was established in 2019 after the merger of four technical ''grandes ...
. André also serves as the President of the European Society for Medical Oncology (ESMO) for the 2025-2026 term.


Early life and education

Fabrice André was born on May 10, 1972. He completed his secondary education in
Villard-de-Lans Villard-de-Lans (, literally ''Villard of Lans''; ) is a commune in the Isère department of the Auvergne-Rhône-Alpes region in southeastern France. The town is also situated in the Vercors Massif. It was the administrative centre of the ep ...
before pursuing higher studies in
Grenoble Grenoble ( ; ; or ; or ) is the Prefectures in France, prefecture and List of communes in France with over 20,000 inhabitants, largest city of the Isère Departments of France, department in the Auvergne-Rhône-Alpes Regions of France, region ...
. He earned a medical degree in oncology from the
University of Grenoble The (, ''Grenoble Alps University'', abbr. UGA) is a Grands établissements, ''grand établissement'' in Grenoble, France. Founded in 1339, it is the third largest university in France with about 60,000 students and over 3,000 researchers. Es ...
in 2002 and obtained a PhD in
Biotechnology Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists ...
from the
University of Paris The University of Paris (), known Metonymy, metonymically as the Sorbonne (), was the leading university in Paris, France, from 1150 to 1970, except for 1793–1806 during the French Revolution. Emerging around 1150 as a corporation associated wit ...
in 2005, with a dissertation on
cancer immunotherapy Cancer immunotherapy (immuno-oncotherapy) is the stimulation of the immune system to treat cancer, improving the immune system's natural ability to fight the disease. It is an application of the basic research, fundamental research of cancer im ...
. André completed his medical oncology residency at Gustave Roussy, where he became a University Professor-Hospital Practitioner in the Department of Medical Oncology in 2012.


Career

From 2010 to 2016, Fabrice André led the Inserm 981/Gustave Roussy/Université Paris-XI joint research unit, focusing on predictive
biomarkers In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, p ...
and molecular strategies in anticancer therapy. He was the first chair of the ESMO Young Oncologist Committee and served as the coordinator of the ESMO Breast Cancer Faculty from 2012 to 2014, remaining a member since 2015. He was also a member of the ESMO Cancer Research Faculty from 2012 to 2014 and chaired the ESMO Translational Research and Precision Medicine Working Group until 2019, continuing as a member from 2020. Additionally, André is a member of the ESMO Council and served as the Scientific Co-Chair of the ESMO 2022 Congress and the MAP Congress. Since 2020, he has been Gustave Roussy's Director of Research. He was a member of the Annals of Oncology editorial Board from 2010 to 2013, became an Associate Editor in 2014, and served as Editor-in-Chief from 2017 to 2023. André was elected President of the European Society for Medical Oncology (ESMO) for the 2025–2026 term, having been selected as President-Elect on June 27, 2022. Additionally, André is the chairman of the biomarker group at UNICANCER, the French cooperative group, and has served on the scientific committees of several international conferences, including SABCS, AACR, ECCO, ESMO, and IMPAKT.


Work

Professor André’s research focuses on biomarkers and personalized therapies, with an emphasis on biomarker discovery, targeted agent development, and the integration of personalized medicine. He leads Phase I-III clinical trials on targeted therapies for
breast cancer Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...
and oversees large-scale national studies on the implementation of high-throughput technologies in healthcare systems. He has authored or co-authored 350 scientific publications in international journals and is recognized as a Highly Cited Researcher by the Web of Science Group. The think tank BIS Research also ranks him among the 25 most influential figures in precision medicine.


Selected publications

* André F, Ciruelos E, Rubovszky G, Campone M, Loibl S, Rugo HS, Iwata H, Conte P, Mayer IA, Kaufman B, Yamashita T, Lu YS, Inoue K, Takahashi M, Pápai Z, Longin AS, Mills D, Wilke C, Hirawat S, Juric D; SOLAR-1 Study Group. Alpelisib for ''PIK3CA''-Mutated, Hormone Receptor-Positive Advanced Breast Cancer. N Engl J Med. 2019 May 16;380(20):1929-1940. doi: 10.1056/NEJMoa1813904. PMID: 31091374. * AACR Project GENIE Consortium. AACR Project GENIE: Powering Precision Medicine through an International Consortium. Cancer Discov. 2017 Aug;7(8):818-831. doi: 10.1158/2159-8290.CD-17-0151. Epub 2017 Jun 1. PMID: 28572459; PMCID: PMC5611790. * Andre F, Schartz NE, Movassagh M, Flament C, Pautier P, Morice P, Pomel C, Lhomme C, Escudier B, Le Chevalier T, Tursz T, Amigorena S, Raposo G, Angevin E, Zitvogel L. Malignant effusions and immunogenic tumor-derived exosomes. Lancet. 2002 Jul 27;360(9329):295-305. doi: 10.1016/S0140-6736(02)09552-1. PMID: 12147373.


Awards and honours

* Outstanding Investigator Award in Breast Cancer – American Association for Cancer Research (AACR) (2021) * Brinker Award for Scientific Distinction in Clinical Research – Susan G. Komen Foundation (2024) * Giants of Cancer Care Award – American Society of Clinical Oncology (ASCO) (2024) * Top 100 Xfluencers in Breast Cancer – OncoDaily (2024)


Reference

{{DEFAULTSORT:Andre, Fabrice Living people Oncology Oncologists