FUB-JWH-018 (also known as FUB-018) is a
naphthoylindole
Naphthoylindoles are a class of synthetic cannabinoids.
Pharmacology
Behaving similarly in vivo to endocannabinoids such as anandamide or 2-arachidonoylglycerol (2-AG), Naphthoylindoles can bind to endocannabinoid receptors in animals, presentin ...
-based
synthetic cannabinoid
Synthetic cannabinoids, or neocannabinoids, are a class of designer drug molecules that Binding affinity, bind to the same receptors to which cannabinoids (Tetrahydrocannabinol, THC, Cannabidiol, CBD and many others) in cannabis plants attach. Th ...
, representing a molecular hybrid of
JWH-018
JWH-018 (1-pentyl-3-(1-naphthoyl)indole, NA-PIMO or AM-678) is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. It produces effe ...
and
AB-FUBICA
AB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptor
Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system of vertebrates a class of cell membrane receptors in the G protein-co ...
or
ADB-FUBICA
ADB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptors, with EC50 values of 2.6 nM at CB1 and 3.0 nM at CB2.
See also
* AB-FUBICA
AB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptor
...
.
Legal status
In the United States, all CB
1 receptor agonists of the 3-(1-naphthoyl)indole class such as FUB-JWH-018 are
Schedule I Controlled Substance
The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated. It was passed by the 91st United State ...
s.
As of October 2015 FUB-JWH-018 is a controlled substance in China.
See also
*
AB-FUBINACA
AB-FUBINACA ( AMB-FUBINACA) is a psychoactive drug that acts as a potent agonist for the cannabinoid receptors, with ''K''i values of 0.9 nM at CB1 and 23.2 nM at CB2 and EC50 values of 1.8 nM at CB1 and 3.2 nM at CB2. I ...
*
ADB-FUBINACA
ADB-FUBINACA (ADMB-FUBINACA) is a designer drug identified in synthetic cannabis blends in Japan in 2013. In 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.
The name ...
*
AMB-FUBINACA
AMB-FUBINACA (also known as FUB-AMB and MMB-FUBINACA) is an indazole-based synthetic cannabinoid that is a potent agonist for the cannabinoid receptors, with ''K''i values of 10.04 nM at CB1 and 0.786 nM at CB2 and EC50 values of ...
*
CHM-018
*
FUB-144
FUB-144 (also known as FUB-UR-144) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. It is an analogue of UR-144 and XLR-11 where the pentyl chain ...
*
FUB-APINACA
FUB-APINACA (also known as A-FUBINACA according to the EMCCDA framework for naming synthetic cannabinoids and FUB-AKB48) is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold on ...
*
FDU-PB-22
FDU-PB-22 is a derivative of JWH-018 that is presumed to be a potent agonist of the CB1 receptor, and has been sold online as a designer drug.
Pharmacology
FDU-PB-22 acts as a full agonist with a binding affinity of 1.19nM at CB1 and 2.43nM at ...
*
FUB-PB-22
FUB-PB-22 (QUFUBIC) is an indole-based synthetic cannabinoid that is a potent agonist of the CB1 receptor and has been sold online as a designer drug.
Pharmacology
FUB-PB-22 acts as a full agonist with a binding affinity of 0.386nM at CB1 ...
*
MDMB-FUBICA
MDMB-FUBICA is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.
It was first detected by the EMCDDA in Sweden in February 2015. It is often sold in e- ...
*
MDMB-FUBINACA
MDMB-FUBINACA (also known as MDMB(N)-Bz-F and FUB-MDMB) is an indazole-based synthetic cannabinoid that is a potent agonist for cannabinoid receptors and that has been sold online as a designer drug. The structure of MDMB-FUBINACA contains the ...
References
Designer drugs
Naphthoylindoles
4-Fluorophenyl compounds
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