Etoxazole is a narrow spectrum systemic

acaricide Acaricides are pesticides that kill members of the arachnid subclass '' Acari'', which includes ticks and mites. Acaricides are used both in medicine and agriculture, although the desired selective toxicity differs between the two fields. Termi ...

used to combat

spider mites Spider mites are members of the family Tetranychidae, which includes about 1,200 species. They are part of the subclass Acari (mites). Spider mites generally live on the undersides of leaves of plants, where they may spin protective silk webs, a ...

. It targets a variety of mites in the egg, larvae and nymph stages however not the adult stage. It also exhibits

insecticidal Insecticides are pesticides used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. The major use of insecticides is in agriculture, but they are also used in home and garden settings, in ...

activity towards

aphid Aphids are small sap-sucking insects in the Taxonomic rank, family Aphididae. Common names include greenfly and blackfly, although individuals within a species can vary widely in color. The group includes the fluffy white Eriosomatinae, woolly ...

s, the

green rice leafhopper Green is the color between cyan and yellow on the visible spectrum. It is evoked by light which has a dominant wavelength of roughly 495570 nm. In subtractive color systems, used in painting and color printing, it is created by a combin ...

and

diamondback moth The diamondback moth (''Plutella xylostella''), sometimes called the cabbage moth, is a moth species of the family Plutellidae and genus '' Plutella''. The small, grayish-brown moth sometimes has a cream-colored band that forms a diamond along ...

. The mode of action has been shown to inhibit

chitin synthase In enzymology, a chitin synthase () is an enzyme that catalyzes the chemical reaction :UDP-N-acetyl-D-glucosamine + ,4-(N-acetyl-beta-D-glucosaminyl) \rightleftharpoons UDP + ,4-(N-acetyl-beta-D-glucosaminyl)+1 Thus, the two substrates of thi ...

(

IRAC IRAC ( ) is an acronym that generally stands for: Issue, Rule, Application, and Conclusion. It functions as a methodology for legal analysis. The IRAC format is mostly used in hypothetical questions in law school and bar exams. Sections of an IR ...

group 10B). Resistance due to its high efficacy and cross resistance when used with other acaricides are both of concern similar to was seen in the fast development of cross resistance in the previous generation of acaricides. The LC₅₀ for resistant mite strains has been observed over 100,000 times greater than that of susceptible strains. Thus resistance management strategies are important in order to limit the increase of etoxazole resistant mite strains. Etoxazole has a mammalian toxicity LD₅₀ of 5 g/kg and an environmental persistence DT₅₀ of 19 days. Toxicity towards fish is of potential concern. Etoxazole was discovered in the 1980s by Yashima and was released for commercial use in 1998 in Japan. It is sold under various commercial preparations for crop application such as TetraSan 5 WDG and Zeal by Valent in the United States.

Stereoisomerism

References

External links

*{{Commons category-inline Acaricides Fluoroarenes Tert-butyl compounds Ethoxy compounds Oxazoles